This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Mouse IL-17 Quantikine ELISA Kit
catalog :
M1700-1
quantity :
1 Kit (1 Plate) (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 125
Reference
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Fan W, Wang X, Zeng S, Li N, Wang G, Li R, et al. Global lactylome reveals lactylation-dependent mechanisms underlying TH17 differentiation in experimental autoimmune uveitis. Sci Adv. 2023;9:eadh4655 pubmed publisher
Ando M, Takahashi M, Mizuno Kamiya M, Morimoto Ito H, Ikeno K, Ueno K, et al. Enhanced production of IL-2 from anti-CD3 antibody-stimulated mouse spleen cells by caffeic acid phenethyl ester, a major component of Chinese propolis. J Oral Biosci. 2023;65:386-394 pubmed publisher
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Tu B, Yu B, Wang W, Li J, Yuan F, Zhu J, et al. Inhibition of IL-17 prevents the progression of traumatic heterotopic ossification. J Cell Mol Med. 2021;25:7709-7719 pubmed publisher
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Chen M, Peng J, Xie Q, Xiao N, Su X, Mei H, et al. Mesenchymal Stem Cells Alleviate Moderate-to-Severe Psoriasis by Reducing the Production of Type I Interferon (IFN-I) by Plasmacytoid Dendritic Cells (pDCs). Stem Cells Int. 2019;2019:6961052 pubmed publisher
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Zuo L, Li J, Ge S, Ge Y, Shen M, Wang Y, et al. Bryostatin-1 ameliorated experimental colitis in Il-10-/- Mice by protecting the intestinal barrier and limiting immune dysfunction. J Cell Mol Med. 2019;23:5588-5599 pubmed publisher
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Kwon Y, Wang H, Denou E, Ghia J, Rossi L, Fontes M, et al. Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis. Cell Mol Gastroenterol Hepatol. 2019;7:709-728 pubmed publisher
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Hoh B, Rojas K, Lin L, Fazal H, Hourani S, Nowicki K, et al. Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin-17A Which Downregulates E-Cadherin. J Am Heart Assoc. 2018;7: pubmed publisher
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Mizukami J, Sato T, Camps M, Ji H, Rueckle T, Swinnen D, et al. ASK1 promotes the contact hypersensitivity response through IL-17 production. Sci Rep. 2014;4:4714 pubmed publisher
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Capitano M, Nemeth M, Mace T, Salisbury Ruf C, Segal B, McCarthy P, et al. Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner. Blood. 2012;120:2600-9 pubmed
Noto Llana M, Sarnacki S, Vázquez M, Gartner A, Giacomodonato M, Cerquetti M. Salmonella enterica induces joint inflammation and expression of interleukin-17 in draining lymph nodes early after onset of enterocolitis in mice. Infect Immun. 2012;80:2231-9 pubmed publisher
Bartemes K, Iijima K, Kobayashi T, Kephart G, McKenzie A, Kita H. IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs. J Immunol. 2012;188:1503-13 pubmed publisher
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Kono H, Fujii H, Ogiku M, Hosomura N, Amemiya H, Tsuchiya M, et al. Role of IL-17A in neutrophil recruitment and hepatic injury after warm ischemia-reperfusion mice. J Immunol. 2011;187:4818-25 pubmed publisher
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Milpied P, Massot B, Renand A, Diem S, Herbelin A, Leite de Moraes M, et al. IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression. Blood. 2011;118:2993-3002 pubmed publisher
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Lindroos J, Svensson L, Norsgaard H, Lovato P, Moller K, Hagedorn P, et al. IL-23-mediated epidermal hyperplasia is dependent on IL-6. J Invest Dermatol. 2011;131:1110-8 pubmed publisher
Li N, Ghia J, Wang H, McClemens J, Cote F, Suehiro Y, et al. Serotonin activates dendritic cell function in the context of gut inflammation. Am J Pathol. 2011;178:662-71 pubmed publisher
Tan C, Aziz M, Lovaas J, Vistica B, Shi G, Wawrousek E, et al. Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site. J Immunol. 2010;185:6795-801 pubmed publisher
Kagami S, Rizzo H, Kurtz S, Miller L, Blauvelt A. IL-23 and IL-17A, but not IL-12 and IL-22, are required for optimal skin host defense against Candida albicans. J Immunol. 2010;185:5453-62 pubmed publisher
Tang H, Pang S, Wang M, Xiao X, Rong Y, Wang H, et al. TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice. J Immunol. 2010;185:2563-9 pubmed publisher
Yoshizaki A, Yanaba K, Iwata Y, Komura K, Ogawa A, Akiyama Y, et al. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. J Immunol. 2010;185:2502-15 pubmed publisher
Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann Koch J, Schirmacher P, et al. Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice. J Exp Med. 2010;207:1617-24 pubmed publisher
Nakajima S, Honda T, Sakata D, Egawa G, Tanizaki H, Otsuka A, et al. Prostaglandin I2-IP signaling promotes Th1 differentiation in a mouse model of contact hypersensitivity. J Immunol. 2010;184:5595-603 pubmed publisher
Ma J, Wang J, Wan J, Charboneau R, Chang Y, Barke R, et al. Morphine disrupts interleukin-23 (IL-23)/IL-17-mediated pulmonary mucosal host defense against Streptococcus pneumoniae infection. Infect Immun. 2010;78:830-7 pubmed publisher
He R, Kim H, Yoon J, Oyoshi M, MacGinnitie A, Goya S, et al. Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13. J Allergy Clin Immunol. 2009;124:761-70.e1 pubmed publisher
Pini M, Fantuzzi G. Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice. J Leukoc Biol. 2010;87:51-8 pubmed publisher
Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton M, et al. A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum. J Immunol. 2009;183:1291-300 pubmed publisher
Gueders M, Paulissen G, Crahay C, Quesada Calvo F, Hacha J, Van Hove C, et al. Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production. Inflamm Res. 2009;58:845-54 pubmed publisher
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Goto M, Murakawa M, Kadoshima Yamaoka K, Tanaka Y, Inoue H, Murafuji H, et al. Phosphodiesterase 7A inhibitor ASB16165 suppresses proliferation and cytokine production of NKT cells. Cell Immunol. 2009;258:147-51 pubmed publisher
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Boniface K, Bak Jensen K, Li Y, Blumenschein W, McGeachy M, McClanahan T, et al. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J Exp Med. 2009;206:535-48 pubmed publisher
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Shigeta A, Matsumoto M, Tedder T, Lowe J, Miyasaka M, Hirata T. An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation. Blood. 2008;112:4915-23 pubmed publisher
Da Silva C, Hartl D, Liu W, Lee C, Elias J. TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol. 2008;181:4279-86 pubmed
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Shinohara M, Kim J, Garcia V, Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity. 2008;29:68-78 pubmed publisher
Ren Y, Lu L, Guo T, Qiu J, Yang Y, Liu A, et al. Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis. J Immunol. 2008;181:1491-8 pubmed
Iwanami K, Matsumoto I, Tanaka Watanabe Y, Inoue A, Mihara M, Ohsugi Y, et al. Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase. Arthritis Rheum. 2008;58:754-63 pubmed publisher
Venkatachalam K, Mummidi S, Cortez D, Prabhu S, Valente A, Chandrasekar B. Resveratrol inhibits high glucose-induced PI3K/Akt/ERK-dependent interleukin-17 expression in primary mouse cardiac fibroblasts. Am J Physiol Heart Circ Physiol. 2008;294:H2078-87 pubmed publisher
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Molesworth Kenyon S, Yin R, Oakes J, Lausch R. IL-17 receptor signaling influences virus-induced corneal inflammation. J Leukoc Biol. 2008;83:401-8 pubmed
McGeachy M, Bak Jensen K, Chen Y, Tato C, Blumenschein W, McClanahan T, et al. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat Immunol. 2007;8:1390-7 pubmed
Wei L, Laurence A, Elias K, O Shea J. IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J Biol Chem. 2007;282:34605-10 pubmed
Brüstle A, Heink S, Huber M, Rosenplänter C, Stadelmann C, Yu P, et al. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat Immunol. 2007;8:958-66 pubmed
Toscano M, Bianco G, Ilarregui J, Croci D, Correale J, Hernandez J, et al. Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death. Nat Immunol. 2007;8:825-34 pubmed
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product information
master code :
M1700
SKU :
M1700-1
product name :
Mouse IL-17 Quantikine ELISA Kit
unit size :
1 Kit (1 Plate) (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Mouse IL-17 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse IL-17/IL-17A in cell culture supernates (50 ul), serum (50 ul), edta plasma (50 ul), heparin plasma (50 ul).
target :
IL-17/IL-17A
category :
ELISAs
species :
Mouse
specificity :
Natural and recombinant mouse IL-17
gene symbol :
Il17a
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)
elisaSensitivity :
5 pg/mL
elisaRange :
10.90 - 700 pg/mL
top caption :
Mouse IL-17/IL-17A ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Mouse IL-17 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse IL-17 in cell culture supernates, serum, and plasma. It contains E. coli -expressed recombinant mouse IL-17 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant mouse IL-17 accurately. Results obtained using natural mouse IL-17 showed linear curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-17.
alt names :
CTLA8, CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.