Mouse IL-12 p40 Allele-specific Quantikine ELISA Kt | R&D Systems M1240 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Mouse IL-12 p40 Allele-specific Quantikine ELISA Kt

catalog :

M1240

quantity :

1 Kit (2 Plates) (also 1 Pack (50 Plates), 1 Pack (6 Plates))

price :

835 USD

citations: 31

Reference
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Still K, Batista S, O Brien C, Oyesola O, Früh S, Webb L, et al. Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling. PLoS Pathog. 2020;16:e1009027 pubmed publisher
Kawabe T, Yi J, Kawajiri A, Hilligan K, Fang D, Ishii N, et al. Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state. Nat Commun. 2020;11:3366 pubmed publisher
Nagaoka M, Yashiro T, Uchida Y, Ando T, Hara M, Arai H, et al. The Orphan Nuclear Receptor NR4A3 Is Involved in the Function of Dendritic Cells. J Immunol. 2017;199:2958-2967 pubmed publisher
Filardy A, Pires D, Nunes M, Takiya C, Freire de Lima C, Ribeiro Gomes F, et al. Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages. J Immunol. 2010;185:2044-50 pubmed publisher
Watanabe T, Asano N, Fichtner Feigl S, Gorelick P, Tsuji Y, Matsumoto Y, et al. NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway. J Clin Invest. 2010;120:1645-62 pubmed publisher
Dorhoi A, Desel C, Yeremeev V, Pradl L, Brinkmann V, Mollenkopf H, et al. The adaptor molecule CARD9 is essential for tuberculosis control. J Exp Med. 2010;207:777-92 pubmed publisher
Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med. 2009;15:1170-8 pubmed publisher
Vultaggio A, Nencini F, Fitch P, Filì L, Maggi L, Fanti P, et al. Modified adenine (9-benzyl-2-butoxy-8-hydroxyadenine) redirects Th2-mediated murine lung inflammation by triggering TLR7. J Immunol. 2009;182:880-9 pubmed
Da Silva C, Hartl D, Liu W, Lee C, Elias J. TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol. 2008;181:4279-86 pubmed
Olleros M, Martin M, Vesin D, Fotio A, Santiago Raber M, Rubbia Brandt L, et al. Fat diet and alcohol-induced steatohepatitis after LPS challenge in mice: role of bioactive TNF and Th1 type cytokines. Cytokine. 2008;44:118-25 pubmed publisher
Voskas D, Babichev Y, Ling L, Alami J, Shaked Y, Kerbel R, et al. An eosinophil immune response characterizes the inflammatory skin disease observed in Tie-2 transgenic mice. J Leukoc Biol. 2008;84:59-67 pubmed publisher
Littlejohn J, Cao X, Miller S, Ozvaran M, Jupiter D, Zhang L, et al. Bcl-xL antisense oligonucleotide and cisplatin combination therapy extends survival in SCID mice with established mesothelioma xenografts. Int J Cancer. 2008;123:202-8 pubmed publisher
Kelschenbach J, Ninkovic J, Wang J, Krishnan A, Charboneau R, Barke R, et al. Morphine withdrawal inhibits IL-12 induction in a macrophage cell line through a mechanism that involves cAMP. J Immunol. 2008;180:3670-9 pubmed
Kaczorowski D, Nakao A, Mollen K, Vallabhaneni R, Sugimoto R, Kohmoto J, et al. Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion. Transplantation. 2007;84:1279-87 pubmed
Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen M, et al. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat Med. 2007;13:1042-9 pubmed
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product information

master code :

M1240

SKU :

M1240

product name :

Mouse IL-12 p40 Allele-specific Quantikine ELISA Kt

unit size :

1 Kit (2 Plates) (also 1 Pack (50 Plates), 1 Pack (6 Plates))

description :

The Mouse IL-12 p40 Allele-specific Quantikine ELISA Kt from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse IL-12/IL-23 p40 in cell culture supernates (50 ul), serum (50 ul).

target :

IL-12/IL-23 p40

category :

ELISAs

species :

Mouse

specificity :

Natural and recombinant mouse IL-12/IL-23 p40

gene symbol :

Il12b

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Serum (50 uL)

elisaSensitivity :

4 pg/mL

elisaRange :

11.70 - 750 pg/mL

top caption :

Mouse IL-12/IL-23 p40 Allele-specific ELISA Standard Curve

applications :

ELISA

USD :

835 USD

product details :

The Quantikine Mouse IL-12/IL-23 p40 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse p40 subunit in IL-12 p70, IL-23, p40 homodimer, and p40 monomer in cell culture supernates and mouse serum. It contains recombinant mouse IL-12 p40 homodimer and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant mouse IL-12/IL-23 p40. Results obtained using natural mouse IL-12/IL-23 p40 showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-12/IL-23 p40.

alt names :

CLMF, CLMF p40, CLMF2, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL12 p40, IL-12 subunit p40, IL12B, IL-12B, IL-12BNK cell stimulatory factor chain 2, interleukin 12, p40, interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocytematuration factor 2, p40), interleukin-12 beta chain, interleukin-12 subunit beta, natural killer cell stimulatory factor, 40 kD subunit, NKSF, NKSF2, NKSF2IL12, subunit p40

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.