Orta Yilmaz B, Aydin Y. New insights into the mechanisms underlying 5-hydroxymethylfurfural-induced suppression of testosterone biosynthesis in vivo and in vitro. Toxicol Appl Pharmacol. 2024;493:117142 pubmed publisher

Justin Margret J, Jain S. The association between alpha-1 antitrypsin and B-type natriuretic peptide blood levels in healthy African Americans. BMC Res Notes. 2024;17:331 pubmed publisher

Ning S, Armstrong C, Xing E, Leslie A, Gao R, Sharifi M, et al. LX1 Dual Targets AR Variants and AKR1C3 in Advanced Prostate Cancer Therapy. Cancer Res. 2024;84:3617-3628 pubmed publisher

Yuan F, Bai K, Hou Y, Zou X, Sun J. Small Molecule Cocktails Promote Fibroblast-to-Leydig-like Cell Conversion for Hypogonadism Therapy. Pharmaceutics. 2023;15: pubmed publisher

Ishizaka T, Horiuchi K, Kondo S, Isaji M, Nakagawa T, Inoue M, et al. Eribulin mesylate induces bone mass loss by promoting osteoclastic bone resorption in mice. Bone Rep. 2023;18:101693 pubmed publisher

Komano Y, Fukao K, Shimada K, Naito H, Ishihara Y, Fujii T, et al. Effects of Ingesting Food Containing Heat-Killed Lactococcus lactis Strain Plasma on Fatigue and Immune-Related Indices after High Training Load: A Randomized, Double-Blind, Placebo-Controlled, and Parallel-Group Study. Nutrients. 2023;15: pubmed publisher

Cho E, Che X, Ang M, Cheon S, Lee J, Kim K, et al. Peroxiredoxin 5 regulates osteogenic differentiation through interaction with hnRNPK during bone regeneration. elife. 2023;12: pubmed publisher

P xe9 rez J, Tolla E, Bishop V, Foster R, Peirson S, Dunn I, et al. Functional inhibition of deep brain non-visual opsins facilitates acute long day induction of reproductive recrudescence in male Japanese quail. Horm Behav. 2023;148:105298 pubmed publisher

Lu J, Liao J, Qin M, Li H, Zhang Q, Chen Y, et al. Single-Cell RNAseq Resolve the Potential Effects of LanCL1 Gene in the Mouse Testis. Cells. 2022;11: pubmed publisher

Hafez H, Waz S, El Tahawy N, Mohamed M. Agomelatine ameliorates cadmium-induced toxicity through the modification of HMGB-1/TLR-4/NFκB pathway. Toxicol Appl Pharmacol. 2022;457:116313 pubmed publisher

Critelli R, Milosa F, Romanzi A, Lasagni S, Marcelli G, Di Marco L, et al. Upregulation of the oestrogen target gene SIX1 is associated with higher growth speed and decreased survival in HCV-positive women with hepatocellular carcinoma. Oncol Lett. 2022;24:395 pubmed publisher

Yao S, Wei X, Deng W, Wang B, Cai J, Huang Y, et al. Nestin-dependent mitochondria-ER contacts define stem Leydig cell differentiation to attenuate male reproductive ageing. Nat Commun. 2022;13:4020 pubmed publisher

Lim W, Forouhan M, Roberts T, Dabney J, Ellerington R, Speciale A, et al. Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity. Sci Adv. 2021;7: pubmed publisher

Bashandy S, Ebaid H, Al Tamimi J, Ahmed Farid O, Omara E, Alhazza I. Melatonin Alleviated Potassium Dichromate-Induced Oxidative Stress and Reprotoxicity in Male Rats. Biomed Res Int. 2021;2021:3565360 pubmed publisher

Zhao H, Song L, Ma N, Liu C, Dun Y, Zhou Z, et al. The dynamic changes of Nrf2 mediated oxidative stress, DNA damage and base excision repair in testis of rats during aging. Exp Gerontol. 2021;152:111460 pubmed publisher

Torres M, López Moncada F, Herrera D, Indo S, Lefian A, Llanos P, et al. Endothelin-1 induces changes in the expression levels of steroidogenic enzymes and increases androgen receptor and testosterone production in the PC3 prostate cancer cell line. Oncol Rep. 2021;46: pubmed publisher

Metzger C, Swallow E, Stacy A, Allen M. Adenine-induced chronic kidney disease induces a similar skeletal phenotype in male and female C57BL/6 mice with more severe deficits in cortical bone properties of male mice. PLoS ONE. 2021;16:e0250438 pubmed publisher

Di Donato M, Zamagni A, Galasso G, Di Zazzo E, Giovannelli P, Barone M, et al. The androgen receptor/filamin A complex as a target in prostate cancer microenvironment. Cell Death Dis. 2021;12:127 pubmed publisher

Jin H, Hou J, Meng X, Ma T, Wang B, Liu Z, et al. Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice. Ecotoxicol Environ Saf. 2021;208:111748 pubmed publisher

Wilharm A, Brigas H, Sandrock I, Ribeiro M, Amado T, Reinhardt A, et al. Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance. Mucosal Immunol. 2021;14:242-252 pubmed publisher

Velletri T, Huang Y, Wang Y, Li Q, Hu M, Xie N, et al. Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin. Cell Death Differ. 2021;28:156-169 pubmed publisher

Eskandari A, Fashi M, Saeidi A, Boullosa D, Laher I, Ben Abderrahman A, et al. Resistance Exercise in a Hot Environment Alters Serum Markers in Untrained Males. Front Physiol. 2020;11:597 pubmed publisher

Zhao H, You X, Chen Q, Yang S, Ma Q, He Y, et al. Icariin Improves Age-Related Testicular Dysfunction by Alleviating Sertoli Cell Injury via Upregulation of the ERα/Nrf2-Signaling Pathway. Front Pharmacol. 2020;11:677 pubmed publisher

Negrón A, Yu G, Boehm U, Acosta Martinez M. Targeted Deletion of PTEN in Kisspeptin Cells Results in Brain Region- and Sex-Specific Effects on Kisspeptin Expression and Gonadotropin Release. Int J Mol Sci. 2020;21: pubmed publisher

Lee D, Kang D, Choi G, Choi H, Cho H. Development of Level A In Vitro-Vivo Correlation for Electrosprayed Microspheres Containing Leuprolide: Physicochemical, Pharmacokinetic, and Pharmacodynamic Evaluation. Pharmaceutics. 2020;12: pubmed publisher

De Toni L, Guidolin D, De Filippis V, Peterle D, Rocca M, Di Nisio A, et al. SHBG141-161 Domain-Peptide Stimulates GPRC6A-Mediated Response in Leydig and β-Langerhans cell lines. Sci Rep. 2019;9:19432 pubmed publisher

Zhao Q, Gao L, Liu Q, Cao Y, He Y, Hu A, et al. Impairment of learning and memory of mice offspring at puberty, young adulthood, and adulthood by low-dose Cd exposure during pregnancy and lactation via GABAAR α5 and δ subunits. Ecotoxicol Environ Saf. 2018;166:336-344 pubmed publisher

Fujita N, Takenaka A. Testosterone represses urinary excretion of the alpha-tocopherol metabolite alpha-carboxymethylhydroxychroman in rats. J Nutr Biochem. 2018;62:59-64 pubmed publisher

Bai Y, Zhu C, Feng M, Wei H, Li L, Tian X, et al. Previously claimed male germline stem cells from porcine testis are actually progenitor Leydig cells. Stem Cell Res Ther. 2018;9:200 pubmed publisher

Allott E, Masko E, Freedland A, Macias E, Pelton K, Solomon K, et al. Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer. Prostate Cancer Prostatic Dis. 2018;21:196-203 pubmed publisher

Lee D, Kim S, Choi G, Lee Y, Cho H. Pharmacokinetic-Pharmacodynamic Model for the Testosterone-Suppressive Effect of Leuprolide in Normal and Prostate Cancer Rats. Molecules. 2018;23: pubmed publisher

Skovgaard C, Christiansen D, Christensen P, Almquist N, Thomassen M, Bangsbo J. Effect of speed endurance training and reduced training volume on running economy and single muscle fiber adaptations in trained runners. Physiol Rep. 2018;6: pubmed publisher

Dou M, Zhu K, Fan Z, Zhang Y, Chen X, Zhou X, et al. Reproductive Hormones and Their Receptors May Affect Lung Cancer. Cell Physiol Biochem. 2017;44:1425-1434 pubmed publisher

Connolly M, Kerse N, Wilkinson T, Menzies O, Rolleston A, Chong Y, et al. Testosterone in advance age: a New Zealand longitudinal cohort study: Life and Living in Advanced Age (Te Pu?waitanga o Ng? Tapuwae Kia Ora Tonu). BMJ Open. 2017;7:e016572 pubmed publisher

Iizuka Hishikawa Y, Hishikawa D, Sasaki J, Takubo K, Goto M, Nagata K, et al. Lysophosphatidic acid acyltransferase 3 tunes the membrane status of germ cells by incorporating docosahexaenoic acid during spermatogenesis. J Biol Chem. 2017;292:12065-12076 pubmed publisher

Matsuda M, Hirata M. Phospholipase C-related but catalytically inactive proteins regulate ovarian follicle development. J Biol Chem. 2017;292:8369-8380 pubmed publisher

Chen J, Meng S, Xu H, Zhang Z, Wu X. Effects of Microcystis on Hypothalamic-Pituitary-Gonadal-Liver Axis in Nile Tilapia (Oreochromis niloticus). Bull Environ Contam Toxicol. 2017;98:562-566 pubmed publisher

Kim N, Nakamura H, Masaki H, Kumasawa K, Hirano K, Kimura T. Effect of lipid metabolism on male fertility. Biochem Biophys Res Commun. 2017;485:686-692 pubmed publisher

Zang Z, Wang J, Chen Z, Zhang Y, Gao Y, Su Z, et al. Transplantation of CD51+ Stem Leydig Cells: A New Strategy for the Treatment of Testosterone Deficiency. Stem Cells. 2017;35:1222-1232 pubmed publisher

Skovgaard C, Almquist N, Bangsbo J. Effect of increased and maintained frequency of speed endurance training on performance and muscle adaptations in runners. J Appl Physiol (1985). 2017;122:48-59 pubmed publisher

Russi A, Walker Caulfield M, Ebel M, Brown M. Cutting edge: c-Kit signaling differentially regulates type 2 innate lymphoid cell accumulation and susceptibility to central nervous system demyelination in male and female SJL mice. J Immunol. 2015;194:5609-13 pubmed publisher

Fan Y, Liu Y, Xue K, Gu G, Fan W, Xu Y, et al. Diet-induced obesity in male C57BL/6 mice decreases fertility as a consequence of disrupted blood-testis barrier. PLoS ONE. 2015;10:e0120775 pubmed publisher

Patel D, Knowell A, Korang Yeboah M, Sharma P, Joshi J, Glymph S, et al. Inhibitor of differentiation 4 (ID4) inactivation promotes de novo steroidogenesis and castration-resistant prostate cancer. Mol Endocrinol. 2014;28:1239-53 pubmed publisher

Lancha A, Rodríguez A, Catalan V, Becerril S, Sainz N, Ramirez B, et al. Osteopontin deletion prevents the development of obesity and hepatic steatosis via impaired adipose tissue matrix remodeling and reduced inflammation and fibrosis in adipose tissue and liver in mice. PLoS ONE. 2014;9:e98398 pubmed publisher

Hu Y, Wang R, Xiang Z, Qian W, Han X, Li D. Antagonistic effects of a mixture of low-dose nonylphenol and di-n-butyl phthalate (monobutyl phthalate) on the Sertoli cells and serum reproductive hormones in prepubertal male rats in vitro and in vivo. PLoS ONE. 2014;9:e93425 pubmed publisher

Zhu T, Griffith J, Qin L, Hung V, Fong T, Au S, et al. Alterations of bone density, microstructure, and strength of the distal radius in male patients with rheumatoid arthritis: a case-control study with HR-pQCT. J Bone Miner Res. 2014;29:2118-29 pubmed publisher

Xue K, Kim J, Liu J, Tsang B. Insulin-like 3-induced rat preantral follicular growth is mediated by growth differentiation factor 9. Endocrinology. 2014;155:156-67 pubmed publisher

Fowler J, Lwin S, Drake M, Edwards J, Kyle R, Mundy G, et al. Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease. Blood. 2011;118:5872-82 pubmed publisher

Betts J, Beelen M, Stokes K, Saris W H, van Loon L J. Endocrine responses during overnight recovery from exercise: impact of nutrition and relationships with muscle protein synthesis. Int J Sport Nutr Exerc Metab. 2011;21:398-409 pubmed

Oatley M, Kaucher A, Racicot K, Oatley J. Inhibitor of DNA binding 4 is expressed selectively by single spermatogonia in the male germline and regulates the self-renewal of spermatogonial stem cells in mice. Biol Reprod. 2011;85:347-56 pubmed publisher

Hong H, Nadesan P, Poon R, Alman B. Testosterone regulates cell proliferation in aggressive fibromatosis (desmoid tumour). Br J Cancer. 2011;104:1452-8 pubmed publisher

Holm L, Haslund M, Robach P, van Hall G, Calbet J, Saltin B, et al. Skeletal muscle myofibrillar and sarcoplasmic protein synthesis rates are affected differently by altitude-induced hypoxia in native lowlanders. PLoS ONE. 2010;5:e15606 pubmed publisher

Jiao Q, Pruznak A, Huber D, Vary T, Lang C. Castration differentially alters basal and leucine-stimulated tissue protein synthesis in skeletal muscle and adipose tissue. Am J Physiol Endocrinol Metab. 2009;297:E1222-32 pubmed publisher

Zhang W, Zhu J, Efferson C, Ware C, Tammam J, Angagaw M, et al. Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer. Cancer Res. 2009;69:7466-72 pubmed publisher