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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Caspase-3 Colorimetric Assay Kit
catalog :
K106
quantity :
100 Tests
price :
389 USD
citations: 74
Reference
Yang C, Chang K, Wang M, Tseng H, Soung H, Fang C, et al. l-Theanine improves functional recovery after traumatic spinal cord injury in rats. J Formos Med Assoc. 2019;: pubmed publisher
He H, Qiao Y, Zhou Q, Wang Z, Chen X, Liu D, et al. Iron Overload Damages the Endothelial Mitochondria via the ROS/ADMA/DDAHII/eNOS/NO Pathway. Oxid Med Cell Longev. 2019;2019:2340392 pubmed publisher
Bral M, Pawlick R, Marfil Garza B, Dadheech N, Hefler J, Thiesen A, et al. Pan-caspase inhibitor F573 mitigates liver ischemia reperfusion injury in a murine model. PLoS ONE. 2019;14:e0224567 pubmed publisher
Park C, Cha H, Choi E, Lee H, Hwang Bo H, Ji S, et al. Isorhamnetin Induces Cell Cycle Arrest and Apoptosis Via Reactive Oxygen Species-Mediated AMP-Activated Protein Kinase Signaling Pathway Activation in Human Bladder Cancer Cells. Cancers (Basel). 2019;11: pubmed publisher
Abo Aasy N, Ragab D, Sallam M, Abdelmonsif D, Aly R, Elkhodairy K. A comparative study: the prospective influence of nanovectors in leveraging the chemopreventive potential of COX-2 inhibitors against skin cancer. Int J Nanomedicine. 2019;14:7561-7581 pubmed publisher
Tsai I, Lin W, Yang Y, Tseng Y, Lin Y, Chou C, et al. High Concentration of C5a-Induced Mitochondria-Dependent Apoptosis in Murine Kidney Endothelial Cells. Int J Mol Sci. 2019;20: pubmed publisher
Tang X, Li H, Zheng X, Lu M, An Y, Zhang X. CRM197 reverses paclitaxel resistance by inhibiting the NAC-1/Gadd45 pathway in paclitaxel-resistant ovarian cancer cells. Cancer Med. 2019;8:6426-6436 pubmed publisher
Cruz Vieira A, Weber A, Ribeiro Y, Luz R, Bazzoli N, Rizzo E. Influence of salinity on spermatogenesis in adult Nile tilapia (Oreochromis niloticus) testis. Theriogenology. 2019;131:1-8 pubmed publisher
Yan L, Xiong C, Xu P, Zhu J, Yang Z, Ren H, et al. Structural characterization and in vitro antitumor activity of A polysaccharide from Artemisia annua L. (Huang Huahao). Carbohydr Polym. 2019;213:361-369 pubmed publisher
Zhang J, Lin Q, Liang F, Xie T. Dexmedetomidine Attenuates Lung Injury by Promoting Mitochondrial Fission and Oxygen Consumption. Med Sci Monit. 2019;25:1848-1856 pubmed publisher
Zhou X, Razmovski Naumovski V, Kam A, Chang D, Li C, Chan K, et al. Synergistic study of a Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination on cell survival in EA.hy926 cells. BMC Complement Altern Med. 2019;19:50 pubmed publisher
Li X, Li Y, Qiu Q, Wen Q, Zhang Q, Yang W, et al. Efficient biofunctionalization of MoS2 nanosheets with peptides as intracellular fluorescent biosensor for sensitive detection of caspase-3 activity. J Colloid Interface Sci. 2019;543:96-105 pubmed publisher
Lee Y, Shu M, Kim J, Kim Y, Sim K, Sung W, et al. Cilostazol protects hepatocytes against alcohol-induced apoptosis via activation of AMPK pathway. PLoS ONE. 2019;14:e0211415 pubmed publisher
Chao X, Wang G, Tang Y, Dong C, Li H, Wang B, et al. The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells. PLoS ONE. 2019;14:e0201864 pubmed publisher
Elsayed N, Serya R, Tolba M, Ahmed M, Barakat K, Abou El Ella D, et al. Design, synthesis, biological evaluation and dynamics simulation of indazole derivatives with antiangiogenic and antiproliferative anticancer activity. Bioorg Chem. 2019;82:340-359 pubmed publisher
Yang Y, Wang G, Wu W, Yao S, Han X, He D, et al. Camalexin Induces Apoptosis via the ROS-ER Stress-Mitochondrial Apoptosis Pathway in AML Cells. Oxid Med Cell Longev. 2018;2018:7426950 pubmed publisher
Tan B, Norhaizan M, Chan L. Manilkara zapota (L.) P. Royen Leaf Water Extract Induces Apoptosis in Human Hepatocellular Carcinoma (HepG2) Cells via ERK1/2/Akt1/JNK1 Signaling Pathways. Evid Based Complement Alternat Med. 2018;2018:7826576 pubmed publisher
Jin C, Molagoda I, Park C, Kwon T, Yun S, Kim W, et al. Piceatannol-Induced Apoptosis Is Reversed by N-Acetyl-L-cysteine through Restoration of XIAP Expression. Biol Pharm Bull. 2018;41:1372-1378 pubmed publisher
Rosca A, Mitroi D, Cismasiu V, Badea R, Necula Petrareanu G, Preda M, et al. Collagen regulates the ability of endothelial progenitor cells to protect hypoxic myocardium through a mechanism involving miR-377/VE-PTP axis. J Cell Mol Med. 2018;22:4700-4708 pubmed publisher
Zhang L, Chen H, Wang M, Song X, Ding F, Zhu J, et al. Effects of glabridin combined with 5-fluorouracil on the proliferation and apoptosis of gastric cancer cells. Oncol Lett. 2018;15:7037-7045 pubmed publisher
Arab H, Salama S, Maghrabi I. Camel Milk Ameliorates 5-Fluorouracil-Induced Renal Injury in Rats: Targeting MAPKs, NF-κB and PI3K/Akt/eNOS Pathways. Cell Physiol Biochem. 2018;46:1628-1642 pubmed publisher
Kim M, Choi E, Hwangbo H, Kwon D, Ahn K, Kim H, et al. Reactive oxygen species-dependent apoptosis induction by water extract of Citrus unshiu peel in MDA-MB-231 human breast carcinoma cells. Nutr Res Pract. 2018;12:129-134 pubmed publisher
Tuo Z, Zhang J, Xue W. LncRNA TP73-AS1 predicts the prognosis of bladder cancer patients and functions as a suppressor for bladder cancer by EMT pathway. Biochem Biophys Res Commun. 2018;499:875-881 pubmed publisher
Lu Y, Cai X, Li Z, Lv J, Xiang Y, Chen J, et al. LncRNA SNHG16 Functions as an Oncogene by Sponging MiR-4518 and Up-Regulating PRMT5 Expression in Glioma. Cell Physiol Biochem. 2018;45:1975-1985 pubmed publisher
van Krüchten A, Wilden J, Niemann S, Peters G, Löffler B, Ludwig S, et al. Staphylococcus aureus triggers a shift from influenza virus-induced apoptosis to necrotic cell death. FASEB J. 2018;32:2779-2793 pubmed publisher
Krishnan P, Rajan M, Kumari S, Sakinah S, Priya S, Amira F, et al. Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug. Sci Rep. 2017;7:10962 pubmed publisher
Nahdi A, John A, Raza H. Elucidation of Molecular Mechanisms of Streptozotocin-Induced Oxidative Stress, Apoptosis, and Mitochondrial Dysfunction in Rin-5F Pancreatic β-Cells. Oxid Med Cell Longev. 2017;2017:7054272 pubmed publisher
Ma Z, Yang Y, Di S, Feng X, Liu D, Jiang S, et al. Pterostilbene exerts anticancer activity on non-small-cell lung cancer via activating endoplasmic reticulum stress. Sci Rep. 2017;7:8091 pubmed publisher
Lee C, Yen F, Ko H, Li S, Chiang Y, Lee M, et al. Cudraflavone C Induces Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS Production and MAPK Activation. Int J Mol Sci. 2017;18: pubmed publisher
Kang K, Han M, Jeong J, Park C, Lee S, Lee H, et al. Bufalin sensitizes human bladder carcinoma cells to TRAIL-mediated apoptosis. Oncol Lett. 2017;14:853-859 pubmed publisher
Kim K, Park K, Kim S, Yu S, Park S, Kim Y, et al. Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells. Int J Mol Sci. 2017;18: pubmed publisher
Fouad A, Qutub H, Fouad A, Audeh A, Al Melhim W. Epigallocatechin-3-gallate counters cisplatin toxicity of rat testes. Pharm Biol. 2017;55:1710-1714 pubmed publisher
Liu W, Zhang Q, Zhang J, Pan W, Zhao J, Xu Y. Long non-coding RNA MALAT1 contributes to cell apoptosis by sponging miR-124 in Parkinson disease. Cell Biosci. 2017;7:19 pubmed publisher
Stuntz E, Gong Y, Sood D, Liaudanskaya V, Pouli D, Quinn K, et al. Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity. Sci Rep. 2017;7:1041 pubmed publisher
Lin M, Tang S, Zhang C, Chen H, Huang W, Liu Y, et al. Euphorbia factor L2 induces apoptosis in A549 cells through the mitochondrial pathway. Acta Pharm Sin B. 2017;7:59-64 pubmed publisher
You B, Han B, Park W. Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-α through up-regulation of TNF receptor 1 in lung cancer cells. Oncotarget. 2017;8:17726-17737 pubmed publisher
Kovacs Z, Kim S, Jikaria N, Qureshi F, Milo B, Lewis B, et al. Disrupting the blood-brain barrier by focused ultrasound induces sterile inflammation. Proc Natl Acad Sci U S A. 2017;114:E75-E84 pubmed publisher
Park S, Park C, Park S, Hong S, Kim G, Hong S, et al. Induction of apoptosis by ethanol extract of Evodia rutaecarpa in HeLa human cervical cancer cells via activation of AMP-activated protein kinase. Biosci Trends. 2017;10:467-476 pubmed publisher
Bae S, Park M, Kang C, Dilmen S, Kang T, Kang D, et al. Hydrogen Peroxide-Responsive Nanoparticle Reduces Myocardial Ischemia/Reperfusion Injury. J Am Heart Assoc. 2016;5: pubmed
Ren H, Chen B, Huang G, Liu Y, Shen D. Upregulation of retinoic acid receptor-? reverses drug resistance in cholangiocarcinoma cells by enhancing susceptibility to apoptosis. Mol Med Rep. 2016;14:3602-8 pubmed publisher
Wang J, Aung L, Prabhakar B, Li P. The mitochondrial ubiquitin ligase plays an anti-apoptotic role in cardiomyocytes by regulating mitochondrial fission. J Cell Mol Med. 2016;20:2278-2288 pubmed publisher
Lee M, Lee S, Kim S, Lee E, Lee H. Anti-Cancer Effect of Lambertianic Acid by Inhibiting the AR in LNCaP Cells. Int J Mol Sci. 2016;17: pubmed publisher
Ko S, Rho D, Jeon J, Kim Y, Woo H, Lee Y, et al. Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinase- and NF-?B-Dependent Pathway, Leading to Modulation of Apoptosis. Infect Immun. 2016;84:2541-54 pubmed publisher
Abedini A, Plesner A, Cao P, Ridgway Z, Zhang J, Tu L, et al. Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics. elife. 2016;5: pubmed publisher
Nordin N, Fadaeinasab M, Mohan S, Mohd Hashim N, Othman R, Karimian H, et al. Pulchrin A, a New Natural Coumarin Derivative of Enicosanthellum pulchrum, Induces Apoptosis in Ovarian Cancer Cells via Intrinsic Pathway. PLoS ONE. 2016;11:e0154023 pubmed publisher
Arab H, Salama S, Omar H, Arafa E, Maghrabi I. Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions. PLoS ONE. 2015;10:e0122417 pubmed publisher
Parvin A, Pranap R, Shalini U, Devendran A, Baker J, Dhanasekaran A. Erythropoietin protects cardiomyocytes from cell death during hypoxia/reperfusion injury through activation of survival signaling pathways. PLoS ONE. 2014;9:e107453 pubmed publisher
Yu P, Petrus M, Ju W, Zhang M, Conlon K, Nakagawa M, et al. Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model. Leukemia. 2015;29:556-66 pubmed publisher
El Halawany A, El Dine R, El Sayed N, Hattori M. Protective effect of Aframomum melegueta phenolics against CCl₄-induced rat hepatocytes damage; role of apoptosis and pro-inflammatory cytokines inhibition. Sci Rep. 2014;4:5880 pubmed publisher
Arab H, Al Shorbagy M, Abdallah D, Nassar N. Telmisartan attenuates colon inflammation, oxidative perturbations and apoptosis in a rat model of experimental inflammatory bowel disease. PLoS ONE. 2014;9:e97193 pubmed publisher
Varatharajalu R, Garige M, Leckey L, Arellanes Robledo J, Reyes Gordillo K, Shah R, et al. Adverse signaling of scavenger receptor class B1 and PGC1s in alcoholic hepatosteatosis and steatohepatitis and protection by betaine in rat. Am J Pathol. 2014;184:2035-44 pubmed publisher
You B, Park W. Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels. Int J Oncol. 2014;44:1745-55 pubmed publisher
El Hachmane M, Rees K, Veale E, Sumbayev V, Mathie A. Enhancement of TWIK-related acid-sensitive potassium channel 3 (TASK3) two-pore domain potassium channel activity by tumor necrosis factor ?. J Biol Chem. 2014;289:1388-401 pubmed publisher
Peng S, Lee C, Hour M, Tsai S, Kuo D, Chen F, et al. Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway. Int J Oncol. 2014;44:238-46 pubmed publisher
Ichihara A, Wang Z, Jinnin M, Izuno Y, Shimozono N, Yamane K, et al. Upregulation of miR-18a-5p contributes to epidermal necrolysis in severe drug eruptions. J Allergy Clin Immunol. 2014;133:1065-74 pubmed publisher
Ko Y, Jeong J, Choi Y, Ryu C. Soy soluble polysaccharide induces apoptosis in HCT‑116 human colon cancer cells via reactive oxygen species generation. Mol Med Rep. 2013;8:1767-72 pubmed publisher
Han B, You B, Park W. Valproic acid inhibits the growth of HeLa cervical cancer cells via caspase-dependent apoptosis. Oncol Rep. 2013;30:2999-3005 pubmed publisher
Weizman N, Krelin Y, Shabtay Orbach A, Amit M, Binenbaum Y, Wong R, et al. Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase. Oncogene. 2014;33:3812-9 pubmed publisher
Barckhausen C, Roos W, Naumann S, Kaina B. Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53-triggered upregulation of DDB2/XPC-mediated DNA repair. Oncogene. 2014;33:1964-74 pubmed publisher
Choi J, Park K, Kim S, Shin J, Jang S. The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice. Molecules. 2013;18:3467-78 pubmed publisher
Liao Y, Lu C, Lai K, Yang J, Kuo S, Wen Y, et al. The novel carboxamide analog ITR-284 induces caspase-dependent apoptotic cell death in human hepatocellular and colorectal cancer cells. Mol Med Rep. 2013;7:1539-44 pubmed publisher
Ehteda A, Galettis P, Pillai K, Morris D. Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice. BMC Cancer. 2013;13:86 pubmed publisher
Jeong H, Nam S, Han N, Kim Y, Kim J, Lee S, et al. The critical role of mast cell-derived hypoxia-inducible factor-1? in human and mice melanoma growth. Int J Cancer. 2013;132:2492-501 pubmed publisher
Raza H, John A. Implications of altered glutathione metabolism in aspirin-induced oxidative stress and mitochondrial dysfunction in HepG2 cells. PLoS ONE. 2012;7:e36325 pubmed publisher
Han M, Lee W, Lu J, Kim G, Jung J, Ryu C, et al. Citrus aurantium L. exhibits apoptotic effects on U937 human leukemia cells partly through inhibition of Akt. Int J Oncol. 2012;40:2090-6 pubmed publisher
Muehlbauer S, Lima H, Goldman D, Jacobson L, Rivera J, Goldberg M, et al. Proteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin. Am J Pathol. 2010;177:735-43 pubmed publisher
Chen J, Zhang M, Ju W, Waldmann T. Effective treatment of a murine model of adult T-cell leukemia using depsipeptide and its combination with unmodified daclizumab directed toward CD25. Blood. 2009;113:1287-93 pubmed publisher
Toscano F, Fajoui Z, Gay F, Lalaoui N, Parmentier B, Chayvialle J, et al. P53-mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells. Oncogene. 2008;27:4161-71 pubmed publisher
Zopf S, Neureiter D, Bouralexis S, Abt T, Glaser K, Okamoto K, et al. Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo. Int J Oncol. 2007;31:1391-402 pubmed
Tsai W, Yeow W, Chua A, Reddy R, Nguyen D, Schrump D, et al. Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin. Mol Cancer Ther. 2006;5:2977-90 pubmed
Karrar A, Broome U, Uzunel M, Qureshi A, Sumitran Holgersson S. Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. Gut. 2007;56:243-52 pubmed
Gibellini D, Vitone F, Schiavone P, Re M. HIV-1 tat protein and cell proliferation and survival: a brief review. New Microbiol. 2005;28:95-109 pubmed
Bardeleben R, Kaina B, Fritz G. Ultraviolet light-induced apoptotic death is impaired by the HMG-CoA reductase inhibitor lovastatin. Biochem Biophys Res Commun. 2003;307:401-7 pubmed
Jiang C, Wang Z, Ganther H, Lu J. Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells. Cancer Res. 2001;61:3062-70 pubmed
product information
brand :
R&D Systems
SKU :
K106
product name :
Caspase-3 Colorimetric Assay Kit
unit sizes :
100 Tests
target :
Caspase-3
category :
Activity Assays
species :
Multi-Species
catalog number base :
K106-100
USD :
389 USD
alt names :
Apopain, apoptosis-related cysteine protease, CASP3, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, Caspase3, CPP32, CPP-32, CPP32B, CPP32SREBP cleavage activity 1, Cysteine protease CPP32, EC 3.4.22, EC 3.4.22.56, LICE-1, PARP cleavage protease, procaspase3, Protein Yama, SCA-1, Yama
storage :
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.