Mouse Osteopontin/OPN PE-conjugated Antibody | R&D Systems IC808P product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Osteopontin/OPN PE-conjugated Antibody

catalog :

IC808P

quantity :

100 Tests

price :

379 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

reactivity :

mouse

application :

immunohistochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 4b	Lu C, Liu Z, Klement J, Yang D, Merting A, Poschel D, et al. WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape. J Immunother Cancer. 2021;9: pubmed publisher
	Li Y, Xue M, Deng X, Dong L, Nguyen L, Ren L, et al. TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal. Cell Stem Cell. 2023;30:1072-1090.e10 pubmed publisher
	Roberts J, Yu M, Viggeswarapu M, Arnst J, Pacifici R, Beck G. Dietary phosphorus consumption alters T cell populations, cytokine production, and bone volume in mice. JCI Insight. 2023;8: pubmed publisher
	Qiu Y, Shen X, Ravid O, Atrakchi D, Rand D, Wight A, et al. Definition of the contribution of an Osteopontin-producing CD11c+ microglial subset to Alzheimer's disease. Proc Natl Acad Sci U S A. 2023;120:e2218915120 pubmed publisher
	Kim S, Lee W, Jo H, Sonn S, Jeong S, Seo S, et al. The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke. Redox Biol. 2022;54:102347 pubmed publisher
	Shen X, Qiu Y, Wight A, Kim H, Cantor H. Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher
	Sato Y, Oguchi A, Fukushima Y, Masuda K, Toriu N, Taniguchi K, et al. CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury. J Clin Invest. 2022;132: pubmed publisher
	Shi L, Sun Z, Su W, Xu F, Xie D, Zhang Q, et al. Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke. Immunity. 2021;54:1527-1542.e8 pubmed publisher
	Wu J, Wu D, Zhang L, Lin C, Liao J, Xie R, et al. NK cells induce hepatic ER stress to promote insulin resistance in obesity through osteopontin production. J Leukoc Biol. 2020;107:589-596 pubmed publisher
	Klement J, Paschall A, Redd P, Ibrahim M, Lu C, Yang D, et al. An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion. J Clin Invest. 2018;128:5549-5560 pubmed publisher
	Suzuki J, Yamada T, Inoue K, Nabe S, Kuwahara M, Takemori N, et al. The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activation. Nat Commun. 2018;9:3296 pubmed publisher
	Guidi N, Sacma M, Ständker L, Soller K, Marka G, Eiwen K, et al. Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells. EMBO J. 2017;36:840-853 pubmed publisher

product information

master code :

IC808P

SKU :

IC808P

product name :

Mouse Osteopontin/OPN PE-conjugated Antibody

unit size :

100 Tests

description :

The Mouse Osteopontin/OPN PE-conjugated Antibody from R&D Systems is a goat polyclonal antibody to Osteopontin/OPN. This antibody reacts with mouse,transgenic mouse. The Mouse Osteopontin/OPN PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Intracellular Staining by Flow Cytometry.

target :

Osteopontin/OPN

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Polyclonal

conjugate :

Phycoerythrin

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Osteopontin/OPN, Leu17-Asn294 (Glu99Gly), Accession # Q547B5

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Transgenic Mouse

specificity :

Detects mouse Osteopontin (OPN) in ELISAs and Western blots. In sandwich ELISAs, less than 3% cross-reactivity with recombinant human OPN is observed.

gene symbol :

SPP1

top caption :

Detection of Osteopontin/OPN antibody in RAW 264.7 Mouse Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q547B5

applications :

Flow Cytometry,Immunohistochemistry,Intracellular Staining by Flow Cytometry

USD :

379 USD

alt names :

BNSP, Bone sialoprotein 1, Eta-1, MGC110940, Nephropontin, OPN, osteopontin, secreted phosphoprotein 1bone sialoprotein I, early T-lymphocyteactivation 1), secreted phosphoprotein-1 (osteopontin, bone sialoprotein), Spp1, SPP-1, SPP1/CALPHA1 fusion, Urinary stone protein, uropontin

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage