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company name :
R&D Systems
product type :
antibody
product name :
Human IL-22 APC-conjugated Antibody
catalog :
IC7821A-100
quantity :
100 Tests (also 25 Tests)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
142928
reactivity :
human
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 12
Reference
Tosi A, Nardinocchi L, Carbone M, Capriotti L, Pagani E, Mastroeni S, et al. Reduced Interleukin-17-Expressing Cells in Cutaneous Melanoma. Biomedicines. 2021;9: pubmed publisher
Utay N, Roque A, Timmer J, Morcock D, Deléage C, Somasunderam A, et al. MRSA Infections in HIV-Infected People Are Associated with Decreased MRSA-Specific Th1 Immunity. PLoS Pathog. 2016;12:e1005580 pubmed publisher
Li L, Jiang Y, Lao S, Yang B, Yu S, Zhang Y, et al. Mycobacterium tuberculosis-Specific IL-21+IFN-γ+CD4+ T Cells Are Regulated by IL-12. PLoS ONE. 2016;11:e0147356 pubmed publisher
Hong M, Sandalova E, Low D, Gehring A, Fieni S, Amadei B, et al. Trained immunity in newborn infants of HBV-infected mothers. Nat Commun. 2015;6:6588 pubmed publisher
Schuetz A, Deléage C, Sereti I, Rerknimitr R, Phanuphak N, Phuang Ngern Y, et al. Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation. PLoS Pathog. 2014;10:e1004543 pubmed publisher
Staumont Sallé D, Fleury S, Lazzari A, Molendi Coste O, Hornez N, Lavogiez C, et al. CX?CL1 (fractalkine) and its receptor CX?CR1 regulate atopic dermatitis by controlling effector T cell retention in inflamed skin. J Exp Med. 2014;211:1185-96 pubmed publisher
Tang X, Jo J, Tan A, Sandalova E, Chia A, Tan K, et al. IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells. J Immunol. 2013;190:3142-52 pubmed publisher
Schmidt J, Iversen A, Tenzer S, Gostick E, Price D, Lohmann V, et al. Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope. PLoS Pathog. 2012;8:e1003042 pubmed publisher
Pennino D, Bhavsar P, Effner R, Avitabile S, Venn P, Quaranta M, et al. IL-22 suppresses IFN-?-mediated lung inflammation in asthmatic patients. J Allergy Clin Immunol. 2013;131:562-70 pubmed publisher
Chan Y, Chen K, Duncan S, Lathrop K, Latoche J, Logar A, et al. Patients with cystic fibrosis have inducible IL-17+IL-22+ memory cells in lung draining lymph nodes. J Allergy Clin Immunol. 2013;131:1117-29, 1129.e1-5 pubmed publisher
Qiao D, Yang B, Li L, Ma J, Zhang X, Lao S, et al. ESAT-6- and CFP-10-specific Th1, Th22 and Th17 cells in tuberculous pleurisy may contribute to the local immune response against Mycobacterium tuberculosis infection. Scand J Immunol. 2011;73:330-7 pubmed publisher
Liu Y, Yang B, Ma J, Wang H, Huang F, Zhang J, et al. Interleukin-21 induces the differentiation of human Tc22 cells via phosphorylation of signal transducers and activators of transcription. Immunology. 2011;132:540-8 pubmed publisher
product information
master code :
IC7821A
SKU :
IC7821A-100
product name :
Human IL-22 APC-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human IL-22 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IL-22. This antibody reacts with human. The Human IL-22 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry-Frozen,Intracellular Staining by Flow Cytometry.
target :
IL-22
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
142928
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
E. coli -derived recombinant human IL-22, Ala34-Ile179, Accession # Q9GZX6
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human IL-22 in direct ELISAs. In direct ELISAs, this antibody shows 100% cross-reactivity with recombinant mouse IL-22 and recombinant rat IL-22 and no cross-reactivity with recombinant human IL-10.
gene symbol :
IL22
top caption :
Detection of IL-22 antibody in Human PBMCs stimulated to induce Th17 Cells antibody by Flow Cytometry.
accessionNumbers :
Q9GZX6
applications :
Flow Cytometry,Immunohistochemistry-Frozen,Intracellular Staining by Flow Cytometry
USD :
469 USD
alt names :
Cytokine Zcyto18, IL-10-related T-cell-derived inducible factor, IL22, IL-D110, IL-TIF, ILTIFIL-10-related T-cell-derived-inducible factor, IL-TIFMGC79382, interleukin 22, interleukin-22, MGC79384, TIFa, TIFIL-23, zcyto18
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.