product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse Arginase 1/ARG1 PE-conjugated Antibody
catalog :
IC5868P
quantity :
100 Tests
price :
429 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
PE
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 31
Reference
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Wang W, Ren X, Chen X, Hong Q, Cai G. Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation. JCI Insight. 2024;9: pubmed publisher
Liu Y, Luo X, Chen Y, Dang J, Zeng D, Guo X, et al. Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis. Redox Biol. 2024;69:103008 pubmed publisher
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Zhou J, Wang H, Shu T, Wang J, Yang W, Li J, et al. Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis. iScience. 2023;26:107626 pubmed publisher
Guan D, Li Y, Cui Y, Zhao H, Dong N, Wang K, et al. 5-HMF attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis mice by inhibiting the MIF-CD74 interaction. Acta Biochim Biophys Sin (Shanghai). 2023;55:1222-1233 pubmed publisher
Gu C, Chen M, Li X, Geng D, Wang C. MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain. Mol Med Rep. 2023;27: pubmed publisher
Do Thi V, Park S, Park S, Jeong H, Cho G, An H, et al. IL9 Polarizes Macrophages to M1 and Induces the Infiltration of Antitumor Immune Cells via MIP-1 and CXCR3 Chemokines. Cancer Res Commun. 2023;3:80-96 pubmed publisher
Huang Y, Chang C, Wu Y, Wu K, Tsai Y, Lee H, et al. Single-Cell Transcriptomic Profiles of Lung Pre-Metastatic Niche Reveal Neutrophil and Lymphatic Endothelial Cell Roles in Breast Cancer. Cancers (Basel). 2022;15: pubmed publisher
Chen F, El Naccache D, Ponessa J, Lemenze A, Espinosa V, Wu W, et al. Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion. Cell Rep. 2022;38:110215 pubmed publisher
Grzywa T, Sosnowska A, Rydzynska Z, Lazniewski M, Plewczynski D, Klicka K, et al. Potent but transient immunosuppression of T-cells is a general feature of CD71+ erythroid cells. Commun Biol. 2021;4:1384 pubmed publisher
Tan X, Yi C, Zhang Y, Tang N, Xu Y, Liu Z. Ultrasound-Targeted Microbubble Destruction Alleviates Immunosuppression Induced by CD71+ Erythroid Progenitor Cells and Promotes PDL-1 Blockade Immunotherapy in the Lewis Lung Cancer Model. Front Oncol. 2021;11:768222 pubmed publisher
Zhang Y, Huang H, Coleman M, Ziemys A, Gopal P, Kazmi S, et al. VEGFR2 activity on myeloid cells mediates immune suppression in the tumor microenvironment. JCI Insight. 2021;6: pubmed publisher
Xu J, Ganguly A, Zhao J, Ivey M, Lopez R, Osterholzer J, et al. CCR2 Signaling Promotes Brain Infiltration of Inflammatory Monocytes and Contributes to Neuropathology during Cryptococcal Meningoencephalitis. MBio. 2021;12:e0107621 pubmed publisher
Marques R, Gonzalez Nuñez M, Walker M, Gómez E, Colas R, Montero Melendez T, et al. Loss of 15-lipoxygenase disrupts Treg differentiation altering their pro-resolving functions. Cell Death Differ. 2021;28:3140-3160 pubmed publisher
Du W, Phinney N, Huang H, Wang Z, Westcott J, Toombs J, et al. AXL Is a Key Factor for Cell Plasticity and Promotes Metastasis in Pancreatic Cancer. Mol Cancer Res. 2021;19:1412-1421 pubmed publisher
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Shakya S, Asosingh K, Mack J, Maytin E. Optimized protocol for the preparation of single cells from cutaneous wounds for flow cytometric cell sorting and analysis of macrophages. MethodsX. 2020;7:101027 pubmed publisher
Miao W, Zhao Y, Huang Y, Chen D, Luo C, Su W, et al. IL-13 Ameliorates Neuroinflammation and Promotes Functional Recovery after Traumatic Brain Injury. J Immunol. 2020;204:1486-1498 pubmed publisher
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Filbey K, Varyani F, Harcus Y, Hewitson J, Smyth D, McSorley H, et al. Macrophage Migration Inhibitory Factor (MIF) Is Essential for Type 2 Effector Cell Immunity to an Intestinal Helminth Parasite. Front Immunol. 2019;10:2375 pubmed publisher
Cai W, Dai X, Chen J, Zhao J, Xu M, Zhang L, et al. STAT6/Arg1 promotes microglia/macrophage efferocytosis and inflammation resolution in stroke mice. JCI Insight. 2019;4: pubmed publisher
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Du W, Huang H, Sorrelle N, Brekken R. Sitravatinib potentiates immune checkpoint blockade in refractory cancer models. JCI Insight. 2018;3: pubmed publisher
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product information
master code :
IC5868P
SKU :
IC5868P
product name :
Human/Mouse Arginase 1/ARG1 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human/Mouse Arginase 1/ARG1 PE-conjugated Antibody from R&D Systems is a sheep polyclonal antibody to Arginase 1/ARG1/liver Arginase. This antibody reacts with human,mouse,transgenic mouse. The Human/Mouse Arginase 1/ARG1 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Intracellular Staining by Flow Cytometry.
target :
Arginase 1/ARG1
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Polyclonal
conjugate :
Phycoerythrin
host :
Sheep
immunogen :
E. coli -derived recombinant human Arginase 1/ARG1, Met1-Lys322, Accession # P05089
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects human, mouse, and rat Arginase 1/ARG1 in direct ELISAs and Western blots.
gene symbol :
ARG1
top caption :
Detection of Arginase 1/ARG1 antibody in HepG2 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P05089
applications :
Flow Cytometry,Intracellular Staining by Flow Cytometry
USD :
429 USD
alt names :
AI, ARG1, arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, EC:3.5.3.1, Liver Arginase, Liver-type arginase, PGIF, Type I Arginase
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.