product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CCL3/MIP-1 alpha PE-conjugated Antibody
catalog :
IC450P
quantity :
100 Tests
price :
379 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
39624
reactivity :
mouse
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 8
Reference
Abdel Hakeem M, Manne S, Beltra J, Stelekati E, Chen Z, Nzingha K, et al. Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation. Nat Immunol. 2021;22:1008-1019 pubmed publisher
Chen Z, Arai E, Khan O, Zhang Z, Ngiow S, He Y, et al. In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer. Cell. 2021;184:1262-1280.e22 pubmed publisher
Smith E, Limbach K, Rangel N, Oda K, Bolton J, Du M, et al. Novel malaria antigen Plasmodium yoelii E140 induces antibody-mediated sterile protection in mice against malaria challenge. PLoS ONE. 2020;15:e0232234 pubmed publisher
Stelekati E, Chen Z, Manne S, Kurachi M, Ali M, Lewy K, et al. Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155. Cell Rep. 2018;23:2142-2156 pubmed publisher
Chen Z, Stelekati E, Kurachi M, Yu S, Cai Z, Manne S, et al. miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb. Cell Rep. 2017;20:2584-2597 pubmed publisher
Xiang B, Baybutt T, Berman Booty L, Magee M, Waldman S, Alexeev V, et al. Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High-Avidity Effector CD8+ T Cells. J Immunol. 2017;198:3507-3514 pubmed publisher
Magee M, Kraft C, Abraham T, Baybutt T, Marszalowicz G, Li P, et al. GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity. Oncoimmunology. 2016;5:e1227897 pubmed
Eberlein J, Nguyen T, Victorino F, Golden Mason L, Rosen H, Homann D. Comprehensive assessment of chemokine expression profiles by flow cytometry. J Clin Invest. 2010;120:907-23 pubmed publisher
product information
master code :
IC450P
SKU :
IC450P
product name :
Mouse CCL3/MIP-1 alpha PE-conjugated Antibody
unit size :
100 Tests
description :
The Mouse CCL3/MIP-1 alpha PE-conjugated Antibody from R&D Systems is a rat monoclonal antibody to CCL3/MIP-1 alpha. This antibody reacts with mouse. The Mouse CCL3/MIP-1 alpha PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Intracellular Staining by Flow Cytometry.
target :
CCL3/MIP-1 alpha
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
39624
conjugate :
Phycoerythrin
host :
Rat
immunogen :
E. coli -derived recombinant mouse CCL3/MIP-1 alpha , Ala24-Ala92, Accession # P10855
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CCL3/MIP-1 alpha in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse CCL4/MIP-1▀ is observed and no cross-reactivity with recombinant human CCL1, 2, 3, 5, 7, 8, 11, 13, 14, 15, 16, 17, 18, 21, 22, 23, 24, 25, 28, recombinant mouse CCL1, 2, 6, 7, 9/10/MIP-1 gamma , 11, 12, 19, 21, 22, 25, 28, recombinant rat CCL2 or CCL20 is observed. Neutralizes the biological activity of recombinant mouse CCL3 and will not block the biological activity of recombinant human CCL3.
gene symbol :
CCL3
top caption :
Detection of CCL3/MIP-1a antibody in LPS-stimulated RAW 264.7 Mouse Cell Line antibody by Flow Cytometry.
accessionNumbers :
P10855
applications :
Flow Cytometry,Intracellular Staining by Flow Cytometry
USD :
379 USD
alt names :
C-C motif chemokine 3, MIP1-(a), AI323804, chemokine (C-C motif) ligand 3, G0S19-1, LD78a, LD78alpha, MIP1 alpha, MIP-1 alpha, Mip1a, MIP-1alpha, MIP1-alpha, PAT 464.1, SCYA3, SIS-beta
storage :
Store the unopened product at 2 - 8░ C. Do not use past expiration date. Protect from light.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.