Human CX3CL1/Fractalkine Chemokine Domain PE-conjugated Antibody

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CX3CL1/Fractalkine Chemokine Domain PE-conjugated Antibody

catalog :

IC365P

quantity :

100 Tests

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

51637

reactivity :

human

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Shin M, You S, Kang Y, Lee N, Yoo S, Park K, et al. DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7RÎ±low and IL-7RÎ±high Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine. J Immunol. 2015;195:2861-9 pubmed publisher
Kassianos A, Wang X, Sampangi S, Afrin S, Wilkinson R, Healy H. Fractalkine-CX3CR1-dependent recruitment and retention of human CD1c+ myeloid dendritic cells by in vitro-activated proximal tubular epithelial cells. Kidney Int. 2015;87:1153-63 pubmed publisher
Truman L, Ford C, Pasikowska M, Pound J, Wilkinson S, Dumitriu I, et al. CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis. Blood. 2008;112:5026-36 pubmed publisher
Hermand P, Pincet F, Carvalho S, Ansanay H, Trinquet E, Daoudi M, et al. Functional adhesiveness of the CX3CL1 chemokine requires its aggregation. Role of the transmembrane domain. J Biol Chem. 2008;283:30225-34 pubmed publisher
Hundhausen C, Schulte A, Schulz B, Andrzejewski M, Schwarz N, von Hundelshausen P, et al. Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes. J Immunol. 2007;178:8064-72 pubmed
Lavergne E, Combadiere B, Bonduelle O, Iga M, Gao J, Maho M, et al. Fractalkine mediates natural killer-dependent antitumor responses in vivo. Cancer Res. 2003;63:7468-74 pubmed

product information

master code :

IC365P

SKU :

IC365P

product name :

Human CX3CL1/Fractalkine Chemokine Domain PE-conjugated Antibody

unit size :

100 Tests

description :

The Human CX3CL1/Fractalkine Chemokine Domain PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CX3CL1/Fractalkine. This antibody reacts with hamster,human,monkey. The Human CX3CL1/Fractalkine Chemokine Domain PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Intracellular Staining by Flow Cytometry.

target :

CX3CL1/Fractalkine

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

51637

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human CX3CL1/Fractalkine Chemokine Domain, Gln25-Arg339 (Ser199Asn) (predicted), Accession # P78423

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CX3CL1/Fractalkine Chemokine Domain in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse CX3CL1 or recombinant rat CX3CL1 is observed.

gene symbol :

CX3CL1

top caption :

Detection of CX3CL1/Fractalkine antibody in NS0 Cell Line Transfected with His-tagged Human CX3CL1 antibody by Flow Cytometry.

accessionNumbers :

P78423

applications :

Flow Cytometry,Intracellular Staining by Flow Cytometry

USD :

369 USD

alt names :

ABCD-3, C3Xkine, chemokine (C-X3-C motif) ligand 1, CX3C membrane-anchored chemokine, CXC3, CXC3C, FKN, fractalkine, Neurotactin, neurotactin), NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, NTTSmall-inducible cytokine D1, SCYD1C-X3-C motif chemokine 1, small inducible cytokine subfamily D (Cys-X3-Cys), member-1

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage