Human CCL4/MIP-1▀ Fluorescein-conjugated Antibody | R&D Systems IC271F product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCL4/MIP-1▀ Fluorescein-conjugated Antibody

catalog :

IC271F

quantity :

100 Tests

price :

329 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

24006

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 12

Reference
Angin M, Wong G, Papagno L, Versmisse P, David A, Bayard C, et al. Preservation of Lymphopoietic Potential and Virus Suppressive Capacity by CD8+ T Cells in HIV-2-Infected Controllers. J Immunol. 2016;197:2787-95 pubmed publisher
van Meijgaarden K, Haks M, Caccamo N, Dieli F, Ottenhoff T, Joosten S. Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset. PLoS Pathog. 2015;11:e1004671 pubmed publisher
Boer M, van Meijgaarden K, Joosten S, Ottenhoff T. CD8+ regulatory T cells, and not CD4+ T cells, dominate suppressive phenotype and function after in vitro live Mycobacterium bovis-BCG activation of human cells. PLoS ONE. 2014;9:e94192 pubmed publisher
Boer M, van Meijgaarden K, Bastid J, Ottenhoff T, Joosten S. CD39 is involved in mediating suppression by Mycobacterium bovis BCG-activated human CD8(+) CD39(+) regulatory T cells. Eur J Immunol. 2013;43:1925-32 pubmed publisher
Ladell K, Hashimoto M, Iglesias M, Wilmann P, McLaren J, Gras S, et al. A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity. 2013;38:425-36 pubmed publisher
Schmidt J, Iversen A, Tenzer S, Gostick E, Price D, Lohmann V, et al. Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope. PLoS Pathog. 2012;8:e1003042 pubmed publisher
Meythaler M, Wang Z, Martinot A, Pryputniewicz S, Kasheta M, McClure H, et al. Early induction of polyfunctional simian immunodeficiency virus (SIV)-specific T lymphocytes and rapid disappearance of SIV from lymph nodes of sooty mangabeys during primary infection. J Immunol. 2011;186:5151-61 pubmed publisher
Guzzo C, Che Mat N, Gee K. Interleukin-27 induces a STAT1/3- and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes. J Biol Chem. 2010;285:24404-11 pubmed publisher
Reeves R, Gillis J, Wong F, Yu Y, Connole M, Johnson R. CD16- natural killer cells: enrichment in mucosal and secondary lymphoid tissues and altered function during chronic SIV infection. Blood. 2010;115:4439-46 pubmed publisher
Eberlein J, Nguyen T, Victorino F, Golden Mason L, Rosen H, Homann D. Comprehensive assessment of chemokine expression profiles by flow cytometry. J Clin Invest. 2010;120:907-23 pubmed publisher
Nobile C, Lind M, Miro F, Chemin K, Tourret M, Occhipinti G, et al. Cognate CD4+ T-cell-dendritic cell interactions induce migration of immature dendritic cells through dissolution of their podosomes. Blood. 2008;111:3579-90 pubmed publisher
Kivioja J, Rinaldi L, Ozenci V, Kouwenhoven M, Kostulas N, Lindgren U, et al. Chemokines and their receptors in whiplash injury: elevated RANTES and CCR-5. J Clin Immunol. 2001;21:272-7 pubmed

product information

master code :

IC271F

SKU :

IC271F

product name :

Human CCL4/MIP-1▀ Fluorescein-conjugated Antibody

unit size :

100 Tests

description :

The Human CCL4/MIP-1ß Fluorescein-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CCL4/MIP-1 beta. This antibody reacts with human,primate - cercocebus atys (sooty mangabey),primate - macaca mulatta (rhesus macaque). The Human CCL4/MIP-1ß Fluorescein-conjugated Antibody has been validated for the following applications: Flow Cytometry,Intracellular Staining by Flow Cytometry.

target :

CCL4/MIP-1 beta

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

24006

conjugate :

Fluorescein

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CCL4/MIP-1▀, Ala24-Asn92, Accession # P13236

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Primate - Cercocebus atys (Sooty Mangabey),Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Detects human CCL4/MIP-1▀ in ELISAs and Western blots. In Western blots, this antibody shows less than 4% cross-reactivity with recombinant human (rh) CCL3/MIP-1 alpha and does not cross-react with recombinant mouse (rm) CCL3/MIP-1 alpha , rmCCL4/MIP-1▀, rhCXCL8/IL-8, rhCCL5, rhCXCL1, rhCXCL2, or rhCXCL3.

gene symbol :

CCL4

top caption :

Detection of CCL4/MIP-1ss antibody in Human Blood Monocytes antibody by Flow Cytometry.

accessionNumbers :

P13236

applications :

Flow Cytometry,Intracellular Staining by Flow Cytometry

USD :

329 USD

alt names :

ACT2, ACT-2, AT744.1, C-C motif chemokine 4, chemokine (C-C motif) ligand 4, Exodus-3, G-26, G-26 T-lymphocyte-secreted protein, HC21, LAG1, LAG-1, Lymphocyte activation gene 1 protein, Macrophage inflammatory protein 1-beta, MIP1 beta, MIP-1 beta, MIP1B, MIP1B1, MIP-1-beta, MIP-1-beta(1-69), PAT 744, Protein H400, SCYA2, SCYA4, secreted protein G-26, SIS-gamma, small inducible cytokine A4 (homologous to mouse Mip-1b), Small-inducible cytokine A4, T-cell activation protein 2

storage :

Store the unopened product at 2 - 8░ C. Do not use past expiration date. Protect from light.

more info or order :

R&D Systems product webpage