product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-15 PE-conjugated Antibody
catalog :
IC2471P
quantity :
100 Tests
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
34559
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 13
Reference
Gulic T, Laskarin G, Glavan L, Grubi x107 Kezele T, Haller H, Rukavina D. Human Decidual CD1a+ Dendritic Cells Undergo Functional Maturation Program Mediated by Gp96. Int J Mol Sci. 2023;24: pubmed publisher
Yang L, Li L, Meng M, Wang W, Yang S, Zhao Y, et al. Evaluation of piggyBac-mediated anti-CD19 CAR-T cells after ex vivo expansion with aAPCs or magnetic beads. J Cell Mol Med. 2021;25:686-700 pubmed publisher
Devocelle A, Lecru L, Francois H, Desterke C, Gallerne C, Eid P, et al. Inhibition of TGF-β1 Signaling by IL-15: A Novel Role for IL-15 in the Control of Renal Epithelial-Mesenchymal Transition: IL-15 Counteracts TGF-β1-Induced EMT in Renal Fibrosis. Int J Cell Biol. 2019;2019:9151394 pubmed publisher
Rekik R, Smiti Khanfir M, Larbi T, Zamali I, Beldi Ferchiou A, Kammoun O, et al. Impaired TGF-β signaling in patients with active systemic lupus erythematosus is associated with an overexpression of IL-22. Cytokine. 2018;108:182-189 pubmed publisher
Gorvel L, Korenfeld D, Tung T, Klechevsky E. Dendritic Cell-Derived IL-32?: A Novel Inhibitory Cytokine of NK Cell Function. J Immunol. 2017;199:1290-1300 pubmed publisher
Azzi S, Gallerne C, Romei C, Le Coz V, Gangemi R, Khawam K, et al. Human Renal Normal, Tumoral, and Cancer Stem Cells Express Membrane-Bound Interleukin-15 Isoforms Displaying Different Functions. Neoplasia. 2015;17:509-17 pubmed publisher
Anguille S, Van Acker H, Van den Bergh J, Willemen Y, Goossens H, Van Tendeloo V, et al. Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner. PLoS ONE. 2015;10:e0123340 pubmed publisher
Williams M, Yousafzai Y, Cox C, Blair A, Carmody R, Sai S, et al. Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia. Blood. 2014;123:3116-27 pubmed publisher
Bastidas S, Graw F, Smith M, Kuster H, Gunthard H, Oxenius A. CD8+ T cells are activated in an antigen-independent manner in HIV-infected individuals. J Immunol. 2014;192:1732-44 pubmed publisher
Arneja A, Johnson H, Gabrovsek L, Lauffenburger D, White F. Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration. J Immunol. 2014;192:123-35 pubmed publisher
Scutera S, Fraone T, Musso T, Cappello P, Rossi S, Pierobon D, et al. Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway. J Immunol. 2009;183:3004-13 pubmed publisher
Hussain S, Kong L, Jordan J, Conrad C, Madden T, Fokt I, et al. A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients. Cancer Res. 2007;67:9630-6 pubmed
Ferlazzo G, Pack M, Thomas D, Paludan C, Schmid D, Strowig T, et al. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. Proc Natl Acad Sci U S A. 2004;101:16606-11 pubmed
product information
brand :
R&D Systems
master code :
IC2471P
SKU :
IC2471P
product name :
Human IL-15 PE-conjugated Antibody
unit size :
100 Tests
seo description :
The Human IL-15 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IL-15. This antibody reacts with human. The Human IL-15 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Intracellular Staining by Flow Cytometry.
target :
IL-15
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
34559
conjugate :
Phycoerythrin
dilution :
Intracellular Staining by Flow Cytometry 10 uL/10^6 cells
host :
Mouse
immunogen :
E. coli -derived recombinant human IL-15, Asn49-Ser162, Accession # P40933
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human IL-15 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2, recombinant mouse IL-15, or rhIL-21 is observed.
gene symbol :
IL15
top caption :
Detection of IL-15 antibody in Human PBMCs antibody by Flow Cytometry.
accessionNumbers :
P40933
applications :
Intracellular Staining by Flow Cytometry,Flow Cytometry
USD :
449 USD
alt names :
IL15, IL-15MGC9721, interleukin 15, interleukin-15
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.