product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse IL-12/IL-35 p35 PE-conjugated Antibody
catalog :
IC2191P
quantity :
100 Tests
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
27537
reactivity :
human, mouse
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 7
Reference
Alshareeda A, Rakha E, Alghwainem A, Alrfaei B, Alsowayan B, Albugami A, et al. The effect of human placental chorionic villi derived mesenchymal stem cell on triple-negative breast cancer hallmarks. PLoS ONE. 2018;13:e0207593 pubmed publisher
Wang H, Kang X, Chu S, Li H, Li X, Yin X, et al. Dysregulated ICOS+ proinflammatory and suppressive regulatory T cells in patients with rheumatoid arthritis. Exp Ther Med. 2018;16:3728-3734 pubmed publisher
Komorowski M, Tisonczyk J, Kolakowska A, Drozdz R, Kozbor D. Modulation of the Tumor Microenvironment by CXCR4 Antagonist-Armed Viral Oncotherapy Enhances the Antitumor Efficacy of Dendritic Cell Vaccines against Neuroblastoma in Syngeneic Mice. Viruses. 2018;10: pubmed publisher
Komorowski M, McGray A, Kolakowska A, Eng K, Gil M, Opyrchal M, et al. Reprogramming antitumor immunity against chemoresistant ovarian cancer by a CXCR4 antagonist-armed viral oncotherapy. Mol Ther Oncolytics. 2016;3:16034 pubmed publisher
Richter C, Thieme S, Bandoła J, Laugsch M, Anastassiadis K, Brenner S. Generation of inducible immortalized dendritic cells with proper immune function in vitro and in vivo. PLoS ONE. 2013;8:e62621 pubmed publisher
Pina A, de Araujo E, Felonato M, Loures F, Feriotti C, Bernardino S, et al. Myeloid dendritic cells (DCs) of mice susceptible to paracoccidioidomycosis suppress T cell responses whereas myeloid and plasmacytoid DCs from resistant mice induce effector and regulatory T cells. Infect Immun. 2013;81:1064-77 pubmed publisher
Long J, Zhang X, Wen M, Kong Q, Lv Z, An Y, et al. IL-35 over-expression increases apoptosis sensitivity and suppresses cell growth in human cancer cells. Biochem Biophys Res Commun. 2013;430:364-9 pubmed publisher
product information
master code :
IC2191P
SKU :
IC2191P
product name :
Human/Mouse IL-12/IL-35 p35 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human/Mouse IL-12/IL-35 p35 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IL-12/IL-35 p35. This antibody reacts with human,mouse. The Human/Mouse IL-12/IL-35 p35 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Intracellular Staining by Flow Cytometry.
target :
IL-12/IL-35 p35
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
27537
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-12/IL-35 p35, Arg23-Ser219, Accession # P29459
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human,Mouse
specificity :
Detects human IL-12/IL-35 p35 in direct ELISAs and Western blots. Detects the p35 subunit either as part of a p40/p35 heterodimer or as a free subunit after reduction of the heterodimer. This antibody does not recognize IL-12 p40 homodimers but shows strong cross-reactivity with the p35 subunits from porcine and mouse systems.
gene symbol :
IL12A
top caption :
Detection of IL-12/IL-35 p35 antibody in Human PBMCs antibody by Flow Cytometry.
accessionNumbers :
P29459
applications :
Flow Cytometry,Intracellular Staining by Flow Cytometry
USD :
459 USD
alt names :
CLMF, CLMF p35, CLMF1, cytotoxic lymphocyte maturation factor 1, p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL12, IL-12, subunit p35, IL12A, IL-12A, IL35 subunit, IL35p35, interleukin 12, p35, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35), interleukin-12 alpha chain, interleukin-12 subunit alpha, NF cell stimulatory factor chain 1, NFSK, NK cell stimulatory factor chain 1, NKSF1, p35
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.