Human/Mouse IL-12/IL-35 p35 APC-conjugated Antibody | R&D Systems IC2191A product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse IL-12/IL-35 p35 APC-conjugated Antibody

catalog :

IC2191A

quantity :

100 Tests

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

27537

reactivity :

human, mouse

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 5

Reference
Alvarez F, Istomine R, da Silva Lira Filho A, Al Aubodah T, Huang D, Okde R, et al. IL-18 is required for the TH1-adaptation of TREG cells and the selective suppression of TH17 responses in acute and chronic infections. Mucosal Immunol. 2023;16:462-475 pubmed publisher
Wu X, Brombacher F, Chroneos Z, Norbury C, Gowda D. IL-4Rα signaling by CD8α+ dendritic cells contributes to cerebral malaria by enhancing inflammatory, Th1, and cytotoxic CD8+ T cell responses. J Biol Chem. 2021;296:100615 pubmed publisher
Duffy S, Keating B, Perera C, Lees J, Tonkin R, Makker P, et al. Regulatory T Cells and Their Derived Cytokine, Interleukin-35, Reduce Pain in Experimental Autoimmune Encephalomyelitis. J Neurosci. 2019;39:2326-2346 pubmed publisher
Wang J, Shi L, Ma C, Ji X, Ying R, Wu X, et al. Differential regulation of interleukin-12 (IL-12)/IL-23 by Tim-3 drives T(H)17 cell development during hepatitis C virus infection. J Virol. 2013;87:4372-83 pubmed publisher
van Herwijnen M, Wieten L, van der Zee R, van Kooten P, Wagenaar Hilbers J, Hoek A, et al. Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis. Proc Natl Acad Sci U S A. 2012;109:14134-9 pubmed publisher

product information

master code :

IC2191A

SKU :

IC2191A

product name :

Human/Mouse IL-12/IL-35 p35 APC-conjugated Antibody

unit size :

100 Tests

description :

The Human/Mouse IL-12/IL-35 p35 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IL-12/IL-35 p35. This antibody reacts with human,mouse. The Human/Mouse IL-12/IL-35 p35 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Intracellular Staining by Flow Cytometry.

target :

IL-12/IL-35 p35

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

27537

conjugate :

Allophycocyanin

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-12/IL-35 p35, Arg23-Ser219, Accession # P29459

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human IL-12/IL-35 p35 in direct ELISAs and Western blots. Detects the p35 subunit either as part of a p40/p35 heterodimer or as a free subunit after reduction of the heterodimer. This antibody does not recognize IL-12 p40 homodimers but shows strong cross-reactivity with the p35 subunits from porcine and mouse systems.

gene symbol :

IL12A

top caption :

Detection of IL-12/IL-35 p35 antibody in Human PBMCs or Mouse Splenocytes antibody by Flow Cytometry.

accessionNumbers :

P29459

applications :

Flow Cytometry,Intracellular Staining by Flow Cytometry

USD :

479 USD

alt names :

CLMF, CLMF p35, CLMF1, cytotoxic lymphocyte maturation factor 1, p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL12, IL-12, subunit p35, IL12A, IL-12A, IL35 subunit, IL35p35, interleukin 12, p35, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35), interleukin-12 alpha chain, interleukin-12 subunit alpha, NF cell stimulatory factor chain 1, NFSK, NK cell stimulatory factor chain 1, NKSF1, p35

storage :

Store the unopened product at 2 - 8░ C. Do not use past expiration date. Protect from light.

more info or order :

R&D Systems product webpage