Human/Mouse HIF-1 alpha/HIF1A PE-conjugated Antibody | R&D Systems IC1935P product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse HIF-1 alpha/HIF1A PE-conjugated Antibody

catalog :

IC1935P

quantity :

100 Tests

price :

429 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

241812

reactivity :

human, mouse

application :

western blot, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 15

Reference
Zhu B, Wei X, Narasimhan H, Qian W, Zhang R, Cheon I, et al. Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in COVID-19. Sci Immunol. 2023;8:eadf0348 pubmed publisher
Park J, Kang I, Kim H, Lee Y, Lee S, Lee H. Obesity enhances antiviral immunity in the genital mucosa through a microbiota-mediated effect on γδ T cells. Cell Rep. 2022;41:111594 pubmed publisher
Jakubison B, Sarkar T, Gudmundsson K, Singh S, Sun L, Morris H, et al. ID2 and HIF-1α collaborate to protect quiescent hematopoietic stem cells from activation, differentiation, and exhaustion. J Clin Invest. 2022;132: pubmed publisher
Sun Y, Lin X, Liu B, Zhang Y, Li W, Zhang S, et al. Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells. Sci Adv. 2021;7:eabj6877 pubmed publisher
Zhu B, Wu Y, Huang S, Zhang R, Son Y, Li C, et al. Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection. Immunity. 2021;54:1200-1218.e9 pubmed publisher
Becker Herman S, Rozenberg M, Hillel Karniel C, Gil Yarom N, Kramer M, Barak A, et al. CD74 is a regulator of hematopoietic stem cell maintenance. PLoS Biol. 2021;19:e3001121 pubmed publisher
Okada M, Kawai K, Sonoda H, Shiratori H, Kishikawa J, Nagata H, et al. Epithelial-mesenchymal transition and metastatic ability of CD133+ colorectal cancer stem-like cells under hypoxia. Oncol Lett. 2021;21:19 pubmed publisher
Codo A, Davanzo G, Monteiro L, de Souza G, Muraro S, Virgilio da Silva J, et al. Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis. Cell Metab. 2020;32:437-446.e5 pubmed publisher
Sellam L, Zappasodi R, Chettibi F, Djennaoui D, Yahi Ait Mesbah N, Amir Tidadini Z, et al. Silibinin down-regulates PD-L1 expression in nasopharyngeal carcinoma by interfering with tumor cell glycolytic metabolism. Arch Biochem Biophys. 2020;690:108479 pubmed publisher
Khatib Massalha E, Bhattacharya S, Massalha H, Biram A, Golan K, Kollet O, et al. Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling. Nat Commun. 2020;11:3547 pubmed publisher
Gemta L, Siska P, Nelson M, Gao X, Liu X, Locasale J, et al. Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8+ T cells. Sci Immunol. 2019;4: pubmed publisher
Duette G, Pereyra Gerber P, Rubione J, Pérez P, Landay A, Crowe S, et al. Induction of HIF-1α by HIV-1 Infection in CD4+ T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation. MBio. 2018;9: pubmed publisher
Okuno T, Kawai K, Hata K, Murono K, Emoto S, Kaneko M, et al. SN-38 Acts as a Radiosensitizer for Colorectal Cancer by Inhibiting the Radiation-induced Up-regulation of HIF-1?. Anticancer Res. 2018;38:3323-3331 pubmed publisher
Lu Y, Liu H, Bi Y, Yang H, Li Y, Wang J, et al. Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis. Cell Mol Immunol. 2018;15:618-629 pubmed publisher
Heyboer M, Milovanova T, Wojcik S, Grant W, Chin M, Hardy K, et al. CD34+/CD45-dim stem cell mobilization by hyperbaric oxygen - changes with oxygen dosage. Stem Cell Res. 2014;12:638-45 pubmed publisher

product information

brand :

R&D Systems

master code :

IC1935P

SKU :

IC1935P

product name :

Human/Mouse HIF-1 alpha/HIF1A PE-conjugated Antibody

unit size :

100 Tests

seo description :

The Human/Mouse HIF-1 alpha/HIF1A PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to HIF-1 alpha. This antibody reacts with human,mouse. The Human/Mouse HIF-1 alpha/HIF1A PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunocytochemistry,Intracellular Staining by Flow Cytometry.

target :

HIF-1 alpha/HIF1A

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

241812

conjugate :

Phycoerythrin

dilution :

Intracellular Staining by Flow Cytometry 10 uL/10^6 cells

host :

Mouse

immunogen :

E. coli -derived recombinant human HIF-1 alpha , Arg575-Asn826, Accession # Q16665.1

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Recognizes human and mouse HIF-1 alpha in direct ELISAs.

gene symbol :

HIF1A

top caption :

Detection of HIF-1a antibody in MCF-7 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q16665.1

applications :

Intracellular Staining by Flow Cytometry,Flow Cytometry,Western Blot,Immunocytochemistry

USD :

429 USD

alt names :

AINT, anti-HIF-1 alpha, anti-HIF1A, ARNT interacting protein, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF 1A, HIF1, HIF1 alpha, HIF-1 alpha, HIF-1a, HIF1A, HIF-1alpha, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1 alpha subunit, hypoxia inducible factor 1 subunit alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1, PAS domain-containing protein 8, PASD8

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage