product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human alpha-Smooth Muscle Actin PE-conjugated Antibody
catalog :
IC1420P
quantity :
100 Tests
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
1A4
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 19
Reference
Miquelestorena Standley E, da Silva A, Monnier M, Chadet S, Piollet M, H xe9 raud A, et al. Human peripheral blood mononuclear cells display a temporal evolving inflammatory profile after myocardial infarction and modify myocardial fibroblasts phenotype. Sci Rep. 2023;13:16745 pubmed publisher
Muchli x144 ska A, Wenta R, x15a ci x144 ska W, Markiewicz A, Suchodolska G, Senkus E, et al. Improved Characterization of Circulating Tumor Cells and Cancer-Associated Fibroblasts in One-Tube Assay in Breast Cancer Patients Using Imaging Flow Cytometry. Cancers (Basel). 2023;15: pubmed publisher
Piotrowska A, Zaucha R, Kr xf3 l O, x17b mijewski M. Vitamin D Modulates the Response of Patient-Derived Metastatic Melanoma Cells to Anticancer Drugs. Int J Mol Sci. 2023;24: pubmed publisher
Salhab A, Amer J, Lu Y, Safadi R. Sodium+/taurocholate cotransporting polypeptide as target therapy for liver fibrosis. Gut. 2021;: pubmed publisher
van Uden D, Koudstaal T, van Hulst J, Bergen I, Gootjes C, Morrell N, et al. Central Role of Dendritic Cells in Pulmonary Arterial Hypertension in Human and Mice. Int J Mol Sci. 2021;22: pubmed publisher
Pustlauk W, Westhoff T, Claeys L, Roch T, Geisler S, Babel N. Induced osteogenic differentiation of human smooth muscle cells as a model of vascular calcification. Sci Rep. 2020;10:5951 pubmed publisher
Segal Salto M, Barashi N, Katav A, Edelshtein V, Aharon A, Hashmueli S, et al. A blocking monoclonal antibody to CCL24 alleviates liver fibrosis and inflammation in experimental models of liver damage. JHEP Rep. 2020;2:100064 pubmed publisher
Swadling L, Pallett L, Diniz M, Baker J, Amin O, Stegmann K, et al. Human Liver Memory CD8+ T Cells Use Autophagy for Tissue Residence. Cell Rep. 2020;30:687-698.e6 pubmed publisher
Yuan Y, Li M, To C, Lam T, Wang P, Yu Y, et al. The Role of the RhoA/ROCK Signaling Pathway in Mechanical Strain-Induced Scleral Myofibroblast Differentiation. Invest Ophthalmol Vis Sci. 2018;59:3619-3629 pubmed publisher
Amer J, Salhab A, Doron S, Morali G, Safadi R. A novel flow cytometry tool for fibrosis scoring through hepatic stellate cell differentiation. Cytometry A. 2018;93:427-435 pubmed publisher
Lo C, Michaeloudes C, Bhavsar P, Huang C, Chang P, Wang C, et al. Reduced suppressive effect of ?2-adrenoceptor agonist on fibrocyte function in severe asthma. Respir Res. 2017;18:194 pubmed publisher
Oak P, Pritzke T, Thiel I, Koschlig M, Mous D, Windhorst A, et al. Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease. EMBO Mol Med. 2017;9:1504-1520 pubmed publisher
Kwan P, Ding J, Tredget E. MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar. PLoS ONE. 2015;10:e0123054 pubmed publisher
Huang L, Nakayama H, Klagsbrun M, Mulliken J, Bischoff J. Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells. Stem Cells. 2015;33:133-45 pubmed publisher
Abu Tair L, Axelrod J, Doron S, Ovadya Y, Krizhanovsky V, Galun E, et al. Natural killer cell-dependent anti-fibrotic pathway in liver injury via Toll-like receptor-9. PLoS ONE. 2013;8:e82571 pubmed publisher
Dendooven A, van Oostrom O, van der Giezen D, Leeuwis J, Snijckers C, Joles J, et al. Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis. Am J Pathol. 2011;178:1069-79 pubmed publisher
Semenov O, Koestenbauer S, Riegel M, Zech N, Zimmermann R, Zisch A, et al. Multipotent mesenchymal stem cells from human placenta: critical parameters for isolation and maintenance of stemness after isolation. Am J Obstet Gynecol. 2010;202:193.e1-193.e13 pubmed publisher
Asosingh K, Aldred M, Vasanji A, Drazba J, Sharp J, Farver C, et al. Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension. Am J Pathol. 2008;172:615-27 pubmed publisher
Nazareth M, Broderick L, Simpson Abelson M, Kelleher R, Yokota S, Bankert R. Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells. J Immunol. 2007;178:5552-62 pubmed
product information
brand :
R&D Systems
master code :
IC1420P
SKU :
IC1420P
product name :
Human alpha-Smooth Muscle Actin PE-conjugated Antibody
unit size :
100 Tests
seo description :
The Human alpha-Smooth Muscle Actin PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to alpha-Smooth Muscle Actin. This antibody reacts with guinea pig,human,mouse. The Human alpha-Smooth Muscle Actin PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunocytochemistry,Intracellular Staining by Flow Cytometry.
target :
alpha-Smooth Muscle Actin
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
1A4
conjugate :
Phycoerythrin
dilution :
Intracellular Staining by Flow Cytometry 10 uL/10^6 cells
host :
Mouse
immunogen :
alpha -Smooth Muscle Actin N-terminal Synthetic Decapeptide
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Guinea Pig,Human,Mouse
specificity :
Detects human alpha -Smooth Muscle Actin.
gene symbol :
ACTA2
top caption :
Detection of a-Smooth Muscle Actin antibody in Human Blood Monocytes antibody by Flow Cytometry.
applications :
Intracellular Staining by Flow Cytometry,Flow Cytometry,Immunohistochemistry,Immunocytochemistry
USD :
429 USD
alt names :
AAT6, ACTA2, Actin alpha 2, actin, alpha 2, smooth muscle, aorta, actin, aortic smooth muscle, ACTSA, ACTVS, alpha 2 actin, alpha SMA, alpha smooth muscle actin, alpha-actin-2, alpha-SMA, alphaSmooth Muscle Actin, a-sma, Cell growth-inhibiting gene 46 protein, growth-inhibiting gene 46, MYMY5, sma, smooth muscle actin
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.