product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human alpha-Smooth Muscle Actin APC-conjugated Antibody
catalog :
IC1420A
quantity :
100 Tests
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
1A4
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry, FACS
more info or order :
citations: 14
Reference
Yonemura A, Semba T, Zhang J, Fan Y, Yasuda Yoshihara N, Wang H, et al. Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment. Cell Rep. 2024;43:113613 pubmed publisher
Hye Jeong J, Park S, Lee S, Kim Y, Kyong Shim I, Jeong S, et al. Orthotopic model of pancreatic cancer using CD34+ humanized mice and generation of tumor organoids from humanized tumors. Int Immunopharmacol. 2023;121:110451 pubmed publisher
Karakas D, Erkisa M, Akar R, Akman G, Senol E, Ulukaya E. Targeting Periostin Expression Makes Pancreatic Cancer Spheroids More Vulnerable to Natural Killer Cells. Biomedicines. 2023;11: pubmed publisher
Malacrida B, Nichols S, Maniati E, Jones R, Delanie Smith R, Roozitalab R, et al. A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion. iScience. 2021;24:102676 pubmed publisher
Delaine Smith R, Maniati E, Malacrida B, Nichols S, Roozitalab R, Jones R, et al. Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer. iScience. 2021;24:102674 pubmed publisher
Kasprzyk Pawelec A, Wojciechowska A, Kuć M, Zieliński J, Parulski A, Kusmierczyk M, et al. microRNA expression profile in Smooth Muscle Cells isolated from thoracic aortic aneurysm samples. Adv Med Sci. 2019;64:331-337 pubmed publisher
Nürnberger S, Lindner C, Maier J, Strohmeier K, Wurzer C, Slezak P, et al. Adipose-tissue-derived therapeutic cells in their natural environment as an autologous cell therapy strategy: the microtissue-stromal vascular fraction. Eur Cell Mater. 2019;37:113-133 pubmed publisher
Shichino S, Ueha S, Hashimoto S, Otsuji M, Abe J, Tsukui T, et al. Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis. JCI Insight. 2019;4: pubmed publisher
Souma K, Shichino S, Hashimoto S, Ueha S, Tsukui T, Nakajima T, et al. Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosis. Sci Rep. 2018;8:16642 pubmed publisher
Costa A, Kieffer Y, Scholer Dahirel A, Pelon F, Bourachot B, Cardon M, et al. Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer. Cancer Cell. 2018;33:463-479.e10 pubmed publisher
Mishima C, Kagara N, Ikeda J, Morii E, Miyake T, Tanei T, et al. Mutational Analysis of AKT1 and PIK3CA in Intraductal Papillomas of the Breast with Special Reference to Cellular Components. Am J Pathol. 2018;188:1106-1112 pubmed publisher
Amati E, Perbellini O, Rotta G, Bernardi M, Chieregato K, Sella S, et al. High-throughput immunophenotypic characterization of bone marrow- and cord blood-derived mesenchymal stromal cells reveals common and differentially expressed markers: identification of angiotensin-converting enzyme (CD143) as a marker differentially. Stem Cell Res Ther. 2018;9:10 pubmed publisher
Li G, Qin L, Wang L, Li X, Caulk A, Zhang J, et al. Inhibition of the mTOR pathway in abdominal aortic aneurysm: implications of smooth muscle cell contractile phenotype, inflammation, and aneurysm expansion. Am J Physiol Heart Circ Physiol. 2017;312:H1110-H1119 pubmed publisher
Chen P, Qin L, Baeyens N, Li G, Afolabi T, Budatha M, et al. Endothelial-to-mesenchymal transition drives atherosclerosis progression. J Clin Invest. 2015;125:4514-28 pubmed publisher
product information
brand :
R&D Systems
master code :
IC1420A
SKU :
IC1420A
product name :
Human alpha-Smooth Muscle Actin APC-conjugated Antibody
unit size :
100 Tests
seo description :
The Human alpha-Smooth Muscle Actin APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to alpha-Smooth Muscle Actin. This antibody reacts with human,mouse. The Human alpha-Smooth Muscle Actin APC-conjugated Antibody has been validated for the following applications: FACS,Flow Cytometry,Immunocytochemistry,Intracellular Staining by Flow Cytometry.
target :
alpha-Smooth Muscle Actin
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
1A4
conjugate :
Allophycocyanin
dilution :
Intracellular Staining by Flow Cytometry 10 uL/10^6 cells
host :
Mouse
immunogen :
alpha -Smooth Muscle Actin N-terminal Synthetic Decapeptide
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human alpha -Smooth Muscle Actin.
gene symbol :
ACTA2
top caption :
Detection of a-Smooth Muscle Actin antibody in Human Blood Monocytes antibody by Flow Cytometry.
applications :
Intracellular Staining by Flow Cytometry,FACS,Flow Cytometry,Immunocytochemistry
USD :
469 USD
alt names :
AAT6, ACTA2, Actin alpha 2, actin, alpha 2, smooth muscle, aorta, actin, aortic smooth muscle, ACTSA, ACTVS, alpha 2 actin, alpha SMA, alpha smooth muscle actin, alpha-actin-2, alpha-SMA, alphaSmooth Muscle Actin, a-sma, Cell growth-inhibiting gene 46 protein, growth-inhibiting gene 46, MYMY5, sma, smooth muscle actin
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.