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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human IL-7 Quantikine HS ELISA Kit
catalog :
HS750
quantity :
1 Kit
price :
695 USD
citations: 45
Reference
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Rajamanickam A, Munisankar S, Bhootra Y, Dolla C, Thiruvengadam K, Nutman T, et al. Altered levels of memory T cell subsets and common γc cytokines in Strongyloides stercoralis infection and partial reversal following anthelmintic treatment. PLoS Negl Trop Dis. 2018;12:e0006481 pubmed publisher
Seyfarth J, Lundtoft C, Förtsch K, Ahlert H, Rosenbauer J, Baechle C, et al. Interleukin-7 receptor α-chain haplotypes differentially affect soluble IL-7 receptor and IL-7 serum concentrations in children with type 1 diabetes. Pediatr Diabetes. 2018;19:955-962 pubmed publisher
Lundtoft C, Afum Adjei Awuah A, Rimpler J, Harling K, Nausch N, Kohns M, et al. Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis. PLoS Pathog. 2017;13:e1006425 pubmed publisher
Ponte R, Rancez M, Figueiredo Morgado S, Dutrieux J, Fabre Mersseman V, Charmeteau de Muylder B, et al. Acute Simian Immunodeficiency Virus Infection Triggers Early and Transient Interleukin-7 Production in the Gut, Leading to Enhanced Local Chemokine Expression and Intestinal Immune Cell Homing. Front Immunol. 2017;8:588 pubmed publisher
Kumar N, Banurekha V, Nair D, Babu S. Diminished plasma levels of common γ-chain cytokines in pulmonary tuberculosis and reversal following treatment. PLoS ONE. 2017;12:e0176495 pubmed publisher
Severino P, Palomino D, Alvarenga H, Almeida C, Pasqualim D, Cury A, et al. Human Lymph Node-Derived Fibroblastic and Double-Negative Reticular Cells Alter Their Chemokines and Cytokines Expression Profile Following Inflammatory Stimuli. Front Immunol. 2017;8:141 pubmed publisher
Cho Y, Kim B, Sim C, Kim I, Lee M. Establishment of IL-7 Expression Reporter Human Cell Lines, and Their Feasibility for High-Throughput Screening of IL-7-Upregulating Chemicals. PLoS ONE. 2016;11:e0161899 pubmed publisher
Okoye A, Rohankhedkar M, Konfe A, Abana C, Reyes M, Clock J, et al. Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques. J Immunol. 2015;195:4292-305 pubmed publisher
Bazdar D, Kalinowska M, Panigrahi S, Sieg S. Recycled IL-7 Can Be Delivered to Neighboring T Cells. J Immunol. 2015;194:4698-704 pubmed publisher
Hannon M, Beguin Y, Ehx G, Servais S, Seidel L, Graux C, et al. Immune Recovery after Allogeneic Hematopoietic Stem Cell Transplantation Following Flu-TBI versus TLI-ATG Conditioning. Clin Cancer Res. 2015;21:3131-9 pubmed publisher
Bruel T, Hamimi C, Dereuddre Bosquet N, Cosma A, Shin S, Corneau A, et al. Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses. J Virol. 2015;89:3542-56 pubmed publisher
Kielsen K, Jordan K, Uhlving H, Pontoppidan P, Shamim Z, Ifversen M, et al. T cell reconstitution in allogeneic haematopoietic stem cell transplantation: prognostic significance of plasma interleukin-7. Scand J Immunol. 2015;81:72-80 pubmed publisher
Cha L, de Jong E, French M, Fernandez S. IFN-? exerts opposing effects on activation-induced and IL-7-induced proliferation of T cells that may impair homeostatic maintenance of CD4+ T cell numbers in treated HIV infection. J Immunol. 2014;193:2178-86 pubmed publisher
Le Saout C, Hasley R, Imamichi H, Tcheung L, Hu Z, Luckey M, et al. Chronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis. PLoS Pathog. 2014;10:e1003976 pubmed publisher
Loubaki L, Hadj Salem I, Fakhfakh R, Jacques E, Plante S, Boisvert M, et al. Co-culture of human bronchial fibroblasts and CD4+ T cells increases Th17 cytokine signature. PLoS ONE. 2013;8:e81983 pubmed publisher
Cai Y, Wang W, Yang Y, Sun L, Teitelbaum D, Yang H. Up-regulation of intestinal epithelial cell derived IL-7 expression by keratinocyte growth factor through STAT1/IRF-1, IRF-2 pathway. PLoS ONE. 2013;8:e58647 pubmed publisher
Zheng M, Zhang Z, Bemis K, Belch A, Pilarski L, Shively J, et al. The systemic cytokine environment is permanently altered in multiple myeloma. PLoS ONE. 2013;8:e58504 pubmed publisher
Kreft K, Verbraak E, Wierenga Wolf A, Van Meurs M, Oostra B, Laman J, et al. Decreased systemic IL-7 and soluble IL-7R? in multiple sclerosis patients. Genes Immun. 2012;13:587-92 pubmed publisher
Vassena L, Miao H, Cimbro R, Malnati M, Cassina G, Proschan M, et al. Treatment with IL-7 prevents the decline of circulating CD4+ T cells during the acute phase of SIV infection in rhesus macaques. PLoS Pathog. 2012;8:e1002636 pubmed publisher
Steel C, Nutman T. Altered T cell memory and effector cell development in chronic lymphatic filarial infection that is independent of persistent parasite antigen. PLoS ONE. 2011;6:e19197 pubmed publisher
Thiant S, Labalette M, Trauet J, Coiteux V, de Berranger E, Dessaint J, et al. Plasma levels of IL-7 and IL-15 after reduced intensity conditioned allo-SCT and relationship to acute GVHD. Bone Marrow Transplant. 2011;46:1374-81 pubmed publisher
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Colucci S, Brunetti G, Cantatore F, Oranger A, Mori G, Quarta L, et al. Lymphocytes and synovial fluid fibroblasts support osteoclastogenesis through RANKL, TNFalpha, and IL-7 in an in vitro model derived from human psoriatic arthritis. J Pathol. 2007;212:47-55 pubmed
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product information
master code :
HS750
SKU :
HS750
product name :
Human IL-7 Quantikine HS ELISA Kit
unit size :
1 Kit
description :
The Human IL-7 Quantikine HS ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human IL-7 in cell culture supernates (200 ul), serum (200 ul), edta plasma (200 ul), citrate plasma (200 ul).
target :
IL-7
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human IL-7
gene symbol :
IL7
kit type :
Solid Phase Sandwich ELISA
assay length :
18-24 hours
elisaSampleTypes :
Cell Culture Supernates (200 uL), Serum (200 uL), EDTA Plasma (200 uL), Citrate Plasma (200 uL)
elisaSensitivity :
0.1 pg/mL
elisaRange :
0.16 - 10 pg/mL (Cell Culture Supernates), 0.25 - 16 pg/mL (Serum, Citrate Plasma, EDTA Plasma)
top caption :
Human IL-7 High Sensitivity ELISA Cell Culture Supernate Standard Curve
applications :
ELISA
USD :
695 USD
product details :
The Quantikine HS Human IL-7 Immunoassay is a solid phase ELISA that specifically measures IL-7 in 18-24 hours (with an overnight incubation step). This kit is designed to measure IL-7 levels in cell culture supernates, serum, and plasma. It contains E. coli -expressed recombinant human IL-7 and antibodies raised against the recombinant factor. It has been shown to quantitate the recombinant factor accurately. Results obtained using natural IL-7 showed linear curves that were parallel to the standard curves obtained using the kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-7.
alt names :
IL7, IL-7interleukin-7, interleukin 7, Lymphopoietin-1, PBGF
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.