product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat p53 HRP-conjugated Antibody
catalog :
HAF1355
quantity :
100 uL
price :
359 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
HRP
reactivity :
human, mouse, rat
application :
western blot
more info or order :
citations: 8
Reference
Mukherjee S, Maddalena M, Lu Y, Martinez S, Nataraj N, Noronha A, et al. Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins. Proc Natl Acad Sci U S A. 2022;119:e2119644119 pubmed publisher
Villot R, Poirier A, Bakan I, Boulay K, Fernández E, Devillers R, et al. ZNF768 links oncogenic RAS to cellular senescence. Nat Commun. 2021;12:4841 pubmed publisher
Mart xed nez No xeb l G, Vieira V, Szajner P, Lilienthal E, Kramer R, Boyland K, et al. Live cell, image-based high-throughput screen to quantitate p53 stabilization and viability in human papillomavirus positive cancer cells. Virology. 2021;560:96-109 pubmed publisher
Bozza W, Takeda K, Alterovitz W, Chou C, Shen R, Zhang B. Anthracycline-Induced Cardiotoxicity: Molecular Insights Obtained from Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs). AAPS J. 2021;23:44 pubmed publisher
George S, Lorenzi F, King D, Hartlieb S, Campbell J, Pemberton H, et al. Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma. EBioMedicine. 2020;59:102971 pubmed publisher
McSweeney K, Bozza W, Alterovitz W, Zhang B. Transcriptomic profiling reveals p53 as a key regulator of doxorubicin-induced cardiotoxicity. Cell Death Discov. 2019;5:102 pubmed publisher
Kühnle S, Martinez Noel G, Leclere F, Hayes S, Harper J, Howley P. Angelman syndrome-associated point mutations in the Zn2+-binding N-terminal (AZUL) domain of UBE3A ubiquitin ligase inhibit binding to the proteasome. J Biol Chem. 2018;293:18387-18399 pubmed publisher
Jethwa A, Słabicki M, Hüllein J, Jentzsch M, Dalal V, Rabe S, et al. TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma. Blood. 2018;: pubmed publisher
product information
brand :
R&D Systems
master code :
HAF1355
SKU :
HAF1355
product name :
Human/Mouse/Rat p53 HRP-conjugated Antibody
unit size :
100 uL
seo description :
The Human/Mouse/Rat p53 HRP-conjugated Antibody from R&D Systems is a goat polyclonal antibody to p53. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat p53 HRP-conjugated Antibody has been validated for the following applications: Western Blot.
target :
p53
category :
Primary Antibodies
buffer :
A 0.2 ╡m filtered solution in Tris with stabilizers and preservatives.
clonality :
Polyclonal
conjugate :
HRP (Horseradish Peroxidase)
dilution :
Western Blot 1:5000 dilution
host :
Goat
immunogen :
E. coli -derived recombinant human p53, Asp7-Asp393, Accession # P04637
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human, mouse, and rat p53 in Western blots.
gene symbol :
TP53
top caption :
Detection of Human p53 antibody by Western Blot.
accessionNumbers :
P04637
applications :
Western Blot
USD :
359 USD
alt names :
Antigen NY-CO-13, BCC7, FLJ92943, LFS1, LFS1TRP53, p53, p53 tumor suppressor, P53cellular tumor antigen p53, Phosphoprotein p53, TP53, transformation-related protein 53, TRP53, tumor protein p53, Tumor suppressor p53
storage :
Do not freeze. 6 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.