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company name :
R&D Systems
product type :
protein
product name :
Caspase-1/ICE Inhibitor Z-WEHD-FMK
catalog :
FMK002
quantity :
1 mg
price :
290 USD
more info or order :
citations: 32
Reference
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Miller A, Hidalgo T, Abrahams V. Human fetal membrane IL-1β production in response to bacterial components is mediated by uric-acid induced NLRP3 inflammasome activation. J Reprod Immunol. 2022;149:103457 pubmed publisher
Elrayess R, Mohallal M, Mobarak Y, Ebaid H, Haywood Small S, Miller K, et al. Scorpion Venom Antimicrobial Peptides Induce Caspase-1 Dependant Pyroptotic Cell Death. Front Pharmacol. 2021;12:788874 pubmed publisher
Ramesova A, Veselá B, Svandová E, Lesot H, Matalova E. Caspase-1 Inhibition Impacts the Formation of Chondrogenic Nodules, and the Expression of Markers Related to Osteogenic Differentiation and Lipid Metabolism. Int J Mol Sci. 2021;22: pubmed publisher
Xu C, Sun S, Johnson T, Qi R, Zhang S, Zhang J, et al. The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity. Cell Rep. 2021;35:109235 pubmed publisher
Abrahams V, Tang Z, Mor G, Guller S. NLRP3 inflammasome function and pyroptotic cell death in human placental Hofbauer cells. J Reprod Immunol. 2020;142:103214 pubmed publisher
Lavallard V, Cottet Dumoulin D, Wassmer C, Rouget C, Parnaud G, Brioudes E, et al. NLRP3 Inflammasome is Activated in Rat Pancreatic Islets by Transplantation and Hypoxia. Sci Rep. 2020;10:7011 pubmed publisher
Talley S, Kalinina O, Winek M, Paik W, Cannon A, Alonzo F, et al. A Caspase-1 Biosensor to Monitor the Progression of Inflammation In Vivo. J Immunol. 2019;203:2497-2507 pubmed publisher
Corleis B, Bucşan A, Deruaz M, Vrbanac V, Lisanti Park A, Gates S, et al. HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis. Cell Rep. 2019;26:1409-1418.e5 pubmed publisher
Ferko M, Catelas I. Effects of metal ions on caspase-1 activation and interleukin-1β release in murine bone marrow-derived macrophages. PLoS ONE. 2018;13:e0199936 pubmed publisher
Gonzalez Juarbe N, Bradley K, Riegler A, Reyes L, Brissac T, Park S, et al. Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During Pneumonia. Sci Rep. 2018;8:5846 pubmed publisher
Kang Y, Zhang H, Zhao Y, Wang Y, Wang W, He Y, et al. Telomere Dysfunction Disturbs Macrophage Mitochondrial Metabolism and the NLRP3 Inflammasome through the PGC-1α/TNFAIP3 Axis. Cell Rep. 2018;22:3493-3506 pubmed publisher
Czimmerer Z, Dániel B, Horvath A, Rückerl D, Nagy G, Kiss M, et al. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. Immunity. 2018;48:75-90.e6 pubmed publisher
Boini K, Hussain T, Li P, Koka S. Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction. Cell Physiol Biochem. 2017;44:152-162 pubmed publisher
Cross S, Potter J, Aldo P, Kwon J, Pitruzzello M, Tong M, et al. Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation. J Immunol. 2017;199:2885-2895 pubmed publisher
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product information
master code :
FMK002
SKU :
FMK002
product name :
Caspase-1/ICE Inhibitor Z-WEHD-FMK
unit size :
1 mg
target :
Caspase-1
category :
Peptides
species :
Multi-Species
USD :
290 USD
alt names :
CASP1, CASP-1, CASP1 nirs variant 1, caspase 1, apoptosis-related cysteine peptidase, caspase-1, Caspase1, Caspase-1 subunit p10, Caspase-1 subunit p20, EC 3.4.22.36, EC:3.4.22.36, ICE, IL-1 beta-converting enzyme, IL1BC, IL-1BC, IL1BCE, IL1B-convertase, interleukin 1, beta, convertase, interleukin 1-B converting enzyme, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45
storage :
Store the unopened product at -20 to -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.