product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ABCG2 APC-conjugated Antibody
catalog :
FAB995A
quantity :
100 Tests
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
5D3
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 6
Reference
Gallerani G, Rossi T, Valgiusti M, Angeli D, Fici P, De Fanti S, et al. CNA Profiling of Single CTCs in Locally Advanced Esophageal Cancer Patients during Therapy Highlights Unexplored Molecular Pathways. Cancers (Basel). 2021;13: pubmed publisher
Zhao Y, Bao Q, Schwarz B, Zhao L, Mysliwietz J, Ellwart J, et al. Stem cell-like side populations in esophageal cancer: a source of chemotherapy resistance and metastases. Stem Cells Dev. 2014;23:180-92 pubmed publisher
Gojo I, Tan M, Fang H, Sadowska M, Lapidus R, Baer M, et al. Translational phase I trial of vorinostat (suberoylanilide hydroxamic acid) combined with cytarabine and etoposide in patients with relapsed, refractory, or high-risk acute myeloid leukemia. Clin Cancer Res. 2013;19:1838-51 pubmed publisher
Ozvegy Laczka C, Laczkó R, Hegedus C, Litman T, Várady G, Goda K, et al. Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter. J Biol Chem. 2008;283:26059-70 pubmed publisher
Keshet G, Goldstein I, Itzhaki O, Cesarkas K, Shenhav L, Yakirevitch A, et al. MDR1 expression identifies human melanoma stem cells. Biochem Biophys Res Commun. 2008;368:930-6 pubmed publisher
Bram E, Ifergan I, Grimberg M, Lemke K, Skladanowski A, Assaraf Y. C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells. Biochem Pharmacol. 2007;74:41-53 pubmed
product information
master code :
FAB995A
SKU :
FAB995A
product name :
Human ABCG2 APC-conjugated Antibody
unit size :
100 Tests
description :
The Human ABCG2 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to ABCG2/CD338. This antibody reacts with human. The Human ABCG2 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry.
target :
ABCG2
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
5D3
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
3T3 cells transduced with human ABCG2
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human ABCG2 in flow cytometry and immunocytochemistry.
gene symbol :
ABCG2
top caption :
Detection of ABCG2 antibody in MCF-7 Human Cell Line antibody by Flow Cytometry.
applications :
Flow Cytometry,Immunocytochemistry
USD :
429 USD
alt names :
ABC transporter, ABC15, ABCP, ABCPMGC102821, ATP-binding cassette sub-family G member 2, ATP-binding cassette transporter G2, ATP-binding cassette, sub-family G (WHITE), member 2, BCRP, BCRP1, BCRPMRX, BMDP, Breast cancer resistance protein, CD338, CD338 antigen, CDw338, EST157481, mitoxantrone resistance protein, Mitoxantrone resistance-associated protein, MXR, MXRMXR1, placenta specific MDR protein, Placenta-specific ATP-binding cassette transporter
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.