product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse ADAM10 Ectodomain PE-conjugated Antibody
catalog :
FAB946P-100UG
quantity :
100 ug
price :
399 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
139712
reactivity :
human, mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 5
Reference
Jones J, Brindley C, Elder N, Myers M, Rajala M, Dekaney C, et al. Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury. Cell Mol Gastroenterol Hepatol. 2019;7:533-554 pubmed publisher
Doi K, Imai T, Kressler C, Yagita H, Agata Y, Vooijs M, et al. Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia. Sci Rep. 2015;5:7978 pubmed publisher
Padro C, Shawler T, Gormley M, Sanders V. Adrenergic regulation of IgE involves modulation of CD23 and ADAM10 expression on exosomes. J Immunol. 2013;191:5383-97 pubmed publisher
Le Gall S, Maretzky T, Issuree P, Niu X, Reiss K, Saftig P, et al. ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site. J Cell Sci. 2010;123:3913-22 pubmed publisher
Mezyk Kopec R, Bzowska M, Stalinska K, Chełmicki T, Podkalicki M, Jucha J, et al. Identification of ADAM10 as a major TNF sheddase in ADAM17-deficient fibroblasts. Cytokine. 2009;46:309-15 pubmed publisher
product information
master code :
FAB946P
SKU :
FAB946P-100UG
product name :
Mouse ADAM10 Ectodomain PE-conjugated Antibody
unit size :
100 ug
description :
The Mouse ADAM10 Ectodomain PE-conjugated Antibody from R&D Systems is a rat monoclonal antibody to ADAM10. This antibody reacts with mouse. The Mouse ADAM10 Ectodomain PE-conjugated Antibody has been validated for the following applications: IHC-F,Flow Cytometry,Immunohistochemistry.
target :
ADAM10
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
139712
conjugate :
Phycoerythrin
host :
Rat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse ADAM10, Thr215-Glu673, Accession # O35598
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse ADAM10 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) rhADAM10 is observed and no cross-reactivity with rhADAM8, recombinant mouse (rm) ADAM9, rmADAM15, rhBACE, or rhTACE is observed.
gene symbol :
ADAM10
top caption :
Detection of ADAM10 antibody in Mouse Splenocytes antibody by Flow Cytometry.
accessionNumbers :
O35598
applications :
IHC-F,Flow Cytometry,Immunohistochemistry
USD :
399 USD
alt names :
a disintegrin and metalloprotease domain 10, a disintegrin and metalloproteinase domain 10, AD10, ADAM 10, ADAM metallopeptidase domain 10, CD156c, CD156c antigen, CDw156, disintegrin and metalloproteinase domain-containing protein 10, EC 3.4.24, HsT18717, kuz, Kuzbanian, Kuzbanian protein homolog, MADM, MADMEC 3.4.24.81, Mammalian disintegrin-metalloprotease
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.