product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human MMP-14/MT1-MMP Alexa Fluor« 488-conjugated Antibody
catalog :
FAB9181G
quantity :
100 Tests
price :
399 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
128527
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 5
Reference
Hey S, Wiesner C, Barcelona B, Linder S. KIF16B drives MT1-MMP recycling in macrophages and promotes co-invasion of cancer cells. Life Sci Alliance. 2023;6: pubmed publisher
Avard R, Broad M, Zandkarimi F, Devanny A, Hammer J, Yu K, et al. DISC-3D: dual-hydrogel system enhances optical imaging and enables correlative mass spectrometry imaging of invading multicellular tumor spheroids. Sci Rep. 2023;13:12383 pubmed publisher
MacKeil J, Brzezinska P, Burke Kleinman J, Craig A, Nicol C, Maurice D. A PKA/cdc42 Signaling Axis Restricts Angiogenic Sprouting by Regulating Podosome Rosette Biogenesis and Matrix Remodeling. Sci Rep. 2019;9:2385 pubmed publisher
Bendris N, Stearns C, Reis C, Rodriguez Canales J, Liu H, Witkiewicz A, et al. Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cells. J Cell Sci. 2016;129:2804-16 pubmed publisher
Loskutov Y, Kozyulina P, Kozyreva V, Ice R, Jones B, Roston T, et al. NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer. Oncogene. 2015;34:3662-75 pubmed publisher
product information
master code :
FAB9181G
SKU :
FAB9181G
product name :
Human MMP-14/MT1-MMP Alexa Fluor« 488-conjugated Antibody
unit size :
100 Tests
description :
The Human MMP-14/MT1-MMP Alexa Fluor® 488-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to MMP-14/MT1-MMP. This antibody reacts with human. The Human MMP-14/MT1-MMP Alexa Fluor® 488-conjugated Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Immunohistochemistry,Immunocytochemistry.
target :
MMP-14/MT1-MMP
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
128527
conjugate :
Alexa Fluor 488
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human MMP-14/MT1-MMP, Tyr112-Ala541 (predicted), Accession # P50281
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human MMP-14/MT1-MMP in direct ELISAs and Western blots. Does not detect E. coli -expressed recombinant human MMP-14 catalytic domain (aa 112-284).
gene symbol :
MMP14
top caption :
Detection of MMP-14/MT1-MMP antibody in MDA-MB-231 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P50281
applications :
Western Blot,Flow Cytometry,Immunohistochemistry,Immunocytochemistry
USD :
399 USD
alt names :
EC 3.4.24, EC 3.4.24.80, matrix metallopeptidase 14 (membrane-inserted), matrix metalloproteinase 14 (membrane-inserted), matrix metalloproteinase-14, membrane type 1 metalloprotease, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP14, MMP-14, MMP-X1, MT1MMP, MT1-MMP, MT1-MMPMTMMP1, MT-MMP 1, MT-MMP1
storage :
Store the unopened product at 2 - 8░ C. Do not use past expiration date. Protect from light.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.