product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Mer APC-conjugated Antibody
catalog :
FAB8912A
quantity :
100 Tests
price :
529 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
125518
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 11
Reference
Lahey K, Varsanyi C, Wang Z, Aquib A, Gadiyar V, Rodrigues A, et al. Regulation of Mertk Surface Expression via ADAM17 and γ-Secretase Proteolytic Processing. Int J Mol Sci. 2024;25: pubmed publisher
Pop O, Geng A, Flint E, Singanayagam A, Ercan C, Possamai L, et al. AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells. Cell Mol Gastroenterol Hepatol. 2023;16:17-37 pubmed publisher
Jung H, Lee S, Lim S, Choi H, Choi Y, Kim M, et al. Anti-inflammatory clearance of amyloid-β by a chimeric Gas6 fusion protein. Nat Med. 2022;28:1802-1812 pubmed publisher
Trovato F, Mujib S, Jerome E, Cavazza A, Morgan P, Smith J, et al. Immunometabolic analysis shows a distinct cyto-metabotype in Covid-19 compared to sepsis from other causes. Heliyon. 2022;8:e09733 pubmed publisher
Medeiros Furquim T, Ayoub S, Johnson L, Aprico A, Nwoke E, Binder M, et al. Cladribine Treatment for MS Preserves the Differentiative Capacity of Subsequently Generated Monocytes, Whereas Its Administration In Vitro Acutely Influences Monocyte Differentiation but Not Microglial Activation. Front Immunol. 2022;13:678817 pubmed publisher
Gattas M, Estecho I, Lago Huvelle M, Errasti A, Carrera Silva E, Simian M. A Heterotypic Tridimensional Model to Study the Interaction of Macrophages and Glioblastoma In Vitro. Int J Mol Sci. 2021;22: pubmed publisher
Nowak W, Grendas L, Sanmarco L, Estecho I, Arena Á, Eberhardt N, et al. Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR. EBioMedicine. 2019;50:290-305 pubmed publisher
Carestia A, Mena H, Olexen C, Ortiz Wilczyñski J, Negrotto S, Errasti A, et al. Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice. Cell Rep. 2019;28:896-908.e5 pubmed publisher
Zapatero Belinchón F, Dietzel E, Dolnik O, Döhner K, Costa R, Hertel B, et al. Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors. Viruses. 2019;11: pubmed publisher
Triantafyllou E, Pop O, Possamai L, Wilhelm A, Liaskou E, Singanayagam A, et al. MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure. Gut. 2018;67:333-347 pubmed publisher
Zheng S, Hedl M, Abraham C. TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages. J Immunol. 2015;194:1928-37 pubmed publisher
product information
master code :
FAB8912A
SKU :
FAB8912A
product name :
Human Mer APC-conjugated Antibody
unit size :
100 Tests
description :
The Human Mer APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Mer. This antibody reacts with human. The Human Mer APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry.
target :
Mer
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
125518
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Mer, Met1-Ala499, Accession # AAB60430
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Mer in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) Axl, rhDtk, or recombinant mouse Mer is observed.
gene symbol :
MERTK
top caption :
Detection of Mer antibody in HepG2 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
AAB60430
applications :
Flow Cytometry,Immunocytochemistry
USD :
529 USD
alt names :
c-Eyk, C-mer, c-mer proto-oncogene tyrosine kinase, EC 2.7.10, EC 2.7.10.1, MER, MER receptor tyrosine kinase, MerTK, MGC133349, Receptor tyrosine kinase MerTK, RP38Proto-oncogene c-Mer, STK kinase, tyrosine-protein kinase Mer
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.