Human Tyro3/Dtk PE-conjugated Antibody | R&D Systems FAB859P product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Tyro3/Dtk PE-conjugated Antibody

catalog :

FAB859P

quantity :

100 Tests

price :

429 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

96201

reactivity :

human

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Gould W, Baxi S, Schroeder R, Peng Y, Leadley R, Peterson J, et al. Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses. J Thromb Haemost. 2005;3:733-41 pubmed
	Mytych J, Pan Z, Lopez Davis C, Redinger N, Lawrence C, Ziegler J, et al. Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3. bioRxiv. 2023;: pubmed publisher
	Xue J, Xu L, Zhu H, Bai M, Li X, Zhao Z, et al. CD14+CD16- monocytes are the main precursors of osteoclasts in rheumatoid arthritis via expressing Tyro3TK. Arthritis Res Ther. 2020;22:221 pubmed publisher
	Holtzhausen A, Harris W, Ubil E, Hunter D, Zhao J, Zhang Y, et al. TAM Family Receptor Kinase Inhibition Reverses MDSC-Mediated Suppression and Augments Anti-PD-1 Therapy in Melanoma. Cancer Immunol Res. 2019;7:1672-1686 pubmed publisher
	Chua B, Ngo J, Situ K, Ramirez C, Nakano H, Morizono K. Protein S and Gas6 induce efferocytosis of HIV-1-infected cells. Virology. 2018;515:176-190 pubmed publisher
	Kasikara C, Kumar S, Kimani S, Tsou W, Geng K, Davra V, et al. Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression. Mol Cancer Res. 2017;15:753-764 pubmed publisher
	Yumoto K, Eber M, Wang J, Cackowski F, Decker A, Lee E, et al. Axl is required for TGF-Î²2-induced dormancy of prostate cancer cells in the bone marrow. Sci Rep. 2016;6:36520 pubmed publisher
	Malawista A, Wang X, Trentalange M, Allore H, Montgomery R. Coordinated expression of tyro3, axl, and mer receptors in macrophage ontogeny. Macrophage (Houst). 2016;3: pubmed
	Zheng S, Hedl M, Abraham C. TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages. J Immunol. 2015;194:1928-37 pubmed publisher

product information

master code :

FAB859P

SKU :

FAB859P

product name :

Human Tyro3/Dtk PE-conjugated Antibody

unit size :

100 Tests

description :

The Human Tyro3/Dtk PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Dtk/TYRO3. This antibody reacts with human. The Human Tyro3/Dtk PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

Tyro3/Dtk

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

96201

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Dtk, Ala41-Ser428 (predicted), Accession # Q06418

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Dtk in ELISAs and Western blots. In ELISAs and Western blots, no cross-reactivity or interference with recombinant mouse Dtk, recombinant human (rh) Axl, or rhMer is observed.

gene symbol :

TYRO3

top caption :

Detection of Dtk antibody in K562 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q06418

applications :

Flow Cytometry

USD :

429 USD

alt names :

Brt, BYK, Dtk, EC 2.7.10, EC 2.7.10.1, FLJ16467, RSE, Sky, Tif, TYRO3 protein tyrosine kinase, Tyrosine-protein kinase byk, Tyrosine-protein kinase DTK, tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage