product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-18 R alpha /IL-1 R5 PE-conjugated Antibody
catalog :
FAB840P-100
quantity :
100 Tests (also 25 Tests)
price :
389 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
70625
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 8
Reference
Shemesh A, Pickering H, Roybal K, Lanier L. Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion. J Exp Med. 2022;219: pubmed publisher
Sundström P, Ahlmanner F, Akéus P, Sundquist M, Alsén S, Yrlid U, et al. Human Mucosa-Associated Invariant T Cells Accumulate in Colon Adenocarcinomas but Produce Reduced Amounts of IFN-γ. J Immunol. 2015;195:3472-81 pubmed publisher
Uzan B, Poglio S, Gerby B, Wu C, Gross J, Armstrong F, et al. Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression. EMBO Mol Med. 2014;6:821-34 pubmed publisher
Salani F, Ciaramella A, Bizzoni F, Assogna F, Caltagirone C, Spalletta G, et al. Increased expression of interleukin-18 receptor in blood cells of subjects with mild cognitive impairment and Alzheimer's disease. Cytokine. 2013;61:360-3 pubmed publisher
Munk R, Sugiyama K, Ghosh P, Sasaki C, Rezanka L, Banerjee K, et al. Antigen-independent IFN-γ production by human naïve CD4 T cells activated by IL-12 plus IL-18. PLoS ONE. 2011;6:e18553 pubmed publisher
Dusseaux M, Martin E, Serriari N, Peguillet I, Premel V, Louis D, et al. Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells. Blood. 2011;117:1250-9 pubmed publisher
de Jager W, Vastert S, Beekman J, Wulffraat N, Kuis W, Coffer P, et al. Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum. 2009;60:2782-93 pubmed publisher
Wu C, Sakorafas P, Miller R, McCarthy D, Scesney S, Dixon R, et al. IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction. J Immunol. 2003;170:5571-7 pubmed
product information
brand :
R&D Systems
master code :
FAB840P
SKU :
FAB840P-100
product name :
Human IL-18 R alpha /IL-1 R5 PE-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
seo description :
The Human IL-18 R alpha /IL-1 R5 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IL-18R alpha/IL-1 R5. This antibody reacts with human. The Human IL-18 R alpha /IL-1 R5 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
IL-18 R alpha/IL-1 R5
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
70625
conjugate :
Phycoerythrin
dilution :
Flow Cytometry 10 uL/10^6 cells
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human IL-18 R alpha /IL-1 R5, Glu20-Arg329, Accession # Q13478
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human IL-18 R alpha /IL-1 R5 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-1 RI, rhIL-1 RII, rhIL-1 R3, rhIL-1 R4, rhIL-1 R6, rhIL-1 R7, rhIL-1 R8, rhIL-1 R9, rhSIGIRR or recombinant mouse IL-18 R alpha is observed.
gene symbol :
IL18R1
top caption :
Detection of IL-18 Ra/IL-1 R5 antibody in Human PBMCs antibody by Flow Cytometry.
accessionNumbers :
Q13478
applications :
Flow Cytometry
USD :
389 USD
alt names :
CD218a, CD218a;CDw218a;IL18R1;IL18RA;IL-18Ralpha;IL-18R-alpha;IL18Ralpha2;IL1RRP;IL-1Rrp;Interleukin-18 receptor 1, IL-1 R5, IL-1 Rrp, IL-18 R1, IL18R alpha, IL18R1, IL-18Ra
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.