product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Siglec-8 PE-conjugated Antibody
catalog :
FAB7975P
quantity :
100 Tests
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
837535
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 4
Reference
Dietschmann A, Schruefer S, Westermann S, Henkel F, Castiglione K, Willebrand R, et al. Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling. MBio. 2022;13:e0123922 pubmed publisher
Vijayakumar B, Boustani K, Ogger P, Papadaki A, Tonkin J, Orton C, et al. Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease. Immunity. 2022;55:542-556.e5 pubmed publisher
Westermann S, Dietschmann A, Doehler D, Castiglione K, Bochner B, Voehringer D, et al. Siglec-F Promotes IL-33-Induced Cytokine Release from Bone Marrow-Derived Eosinophils Independently of the ITIM and ITIM-like Motif Phosphorylation. J Immunol. 2022;208:732-744 pubmed publisher
Youngblood B, Brock E, Leung J, Falahati R, Bochner B, Rasmussen H, et al. Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis. JCI Insight. 2019;4: pubmed publisher
product information
master code :
FAB7975P
SKU :
FAB7975P
product name :
Human Siglec-8 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human Siglec-8 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Siglec-8. This antibody reacts with human. The Human Siglec-8 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
Siglec-8
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
837535
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Siglec-8, Met17-Ala363, Accession # Q9NYZ4
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Siglec-8 in ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Siglec-7, -9, or -14 is observed.
gene symbol :
SIGLEC8
top caption :
Detection of Siglec-8 antibody in Human Blood Granulocytes antibody by Flow Cytometry.
accessionNumbers :
Q9NYZ4
applications :
Flow Cytometry
USD :
429 USD
alt names :
CD329 antigen, CDw329, MGC59785, SAF2, SAF2SAF-2, sialic acid binding Ig-like lectin 8, Sialoadhesin family member 2, Siglec8, Siglec-8, SIGLEC8L, SIGLEC8Lsialic acid-binding Ig-like lectin 8
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.