product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CD74 APC-conjugated Antibody
catalog :
FAB7478A
quantity :
100 Tests
price :
389 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
829706
reactivity :
mouse
application :
neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 4
Reference
Qiu Z, Khalife J, Lin A, Ethiraj P, Jaafar C, Chiou L, et al. IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHC CII complexes. bioRxiv. 2023;: pubmed publisher
Li X, Abrahams C, Yu A, Embry M, Henningsen R, Dealmeida V, et al. Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001. Oncotarget. 2023;14:1-13 pubmed publisher
Becker Herman S, Rozenberg M, Hillel Karniel C, Gil Yarom N, Kramer M, Barak A, et al. CD74 is a regulator of hematopoietic stem cell maintenance. PLoS Biol. 2021;19:e3001121 pubmed publisher
Klasen C, Ohl K, Sternkopf M, Shachar I, Schmitz C, Heussen N, et al. MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling. J Immunol. 2014;192:5273-84 pubmed publisher
product information
master code :
FAB7478A
SKU :
FAB7478A
product name :
Mouse CD74 APC-conjugated Antibody
unit size :
100 Tests
description :
The Mouse CD74 APC-conjugated Antibody from R&D Systems is a rat monoclonal antibody to CD74. This antibody reacts with mouse. The Mouse CD74 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Neutralization.
target :
CD74
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
829706
conjugate :
Allophycocyanin
host :
Rat
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant mouse CD74, Gln56-Cys215, Accession # P04441
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CD74 in ELISAs.
gene symbol :
CD74
top caption :
Detection of CD74 antibody in A20 Mouse Cell Line antibody by Flow Cytometry.
accessionNumbers :
P04441
applications :
Flow Cytometry,Neutralization
USD :
389 USD
alt names :
CD74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated), CD74 molecule, major histocompatibility complex, class II invariant chain, CLIP, DHLAG, DHLAGgamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, Ii, INVG34, MHC HLA-DR gamma chain, p33
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.