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company name :
R&D Systems
product type :
antibody
product name :
Mouse CCR3 Fluorescein-conjugated Antibody
catalog :
FAB729F-025
quantity :
25 Tests (also 100 Tests)
price :
139 USD
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
83101
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
citations: 27
Reference
Lee J, Kim S, Choi G, Yi E, Park H, Choi W, et al. Sweet taste receptor agonists attenuate macrophage IL-1β expression and eosinophilic inflammation linked to autophagy deficiency in myeloid cells. Clin Transl Med. 2022;12:e1021 pubmed publisher
Iwasaki N, Terawaki S, Shimizu K, Oikawa D, Sakamoto H, Sunami K, et al. Th2 cells and macrophages cooperatively induce allergic inflammation through histamine signaling. PLoS ONE. 2021;16:e0248158 pubmed publisher
Dileepan M, Ge X, Bastan I, Greenberg Y, Liang Y, Sriramarao P, et al. Regulation of Eosinophil Recruitment and Allergic Airway Inflammation by Tropomyosin Receptor Kinase A. J Immunol. 2020;204:682-693 pubmed publisher
Yasuda K, Adachi T, Koida A, Nakanishi K. Nematode-Infected Mice Acquire Resistance to Subsequent Infection With Unrelated Nematode by Inducing Highly Responsive Group 2 Innate Lymphoid Cells in the Lung. Front Immunol. 2018;9:2132 pubmed publisher
Bastan I, Ge X, Dileepan M, Greenberg Y, Guedes A, Hwang S, et al. Inhibition of soluble epoxide hydrolase attenuates eosinophil recruitment and food allergen-induced gastrointestinal inflammation. J Leukoc Biol. 2018;104:109-122 pubmed publisher
Rozenberg P, Reichman H, Zab Bar I, Itan M, Pasmanik Chor M, Bouffi C, et al. CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production. Sci Rep. 2017;7:5922 pubmed publisher
Ochkur S, Doyle A, Jacobsen E, Lesuer W, Li W, Protheroe C, et al. Frontline Science: Eosinophil-deficient MBP-1 and EPX double-knockout mice link pulmonary remodeling and airway dysfunction with type 2 inflammation. J Leukoc Biol. 2017;102:589-599 pubmed publisher
Olsson A, Venkatasubramanian M, Chaudhri V, Aronow B, Salomonis N, Singh H, et al. Single-cell analysis of mixed-lineage states leading to a binary cell fate choice. Nature. 2016;537:698-702 pubmed publisher
Lu T, Rothenberg M. Bone Marrow Derived Eosinophil Cultures. Bio Protoc. 2014;4: pubmed
Ge X, Ha S, Greenberg Y, Rao A, Bastan I, Blidner A, et al. Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1. Proc Natl Acad Sci U S A. 2016;113:E4837-46 pubmed publisher
Schollaert K, Stephens M, Gray J, Fulkerson P. Generation of eosinophils from cryopreserved murine bone marrow cells. PLoS ONE. 2014;9:e116141 pubmed publisher
Takeda K, Shiraishi Y, Ashino S, Han J, Jia Y, Wang M, et al. Eosinophils contribute to the resolution of lung-allergic responses following repeated allergen challenge. J Allergy Clin Immunol. 2015;135:451-60 pubmed publisher
Doyle A, Jacobsen E, Ochkur S, Willetts L, Shim K, Neely J, et al. Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing Cre recombinase exclusively in eosinophils. J Leukoc Biol. 2013;94:17-24 pubmed publisher
Ge X, Ha S, Liu F, Rao S, Sriramarao P. Eosinophil-expressed galectin-3 regulates cell trafficking and migration. Front Pharmacol. 2013;4:37 pubmed publisher
Lu T, Lim E, Itskovich S, Besse J, Plassard A, Mingler M, et al. Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth. PLoS ONE. 2013;8:e59397 pubmed publisher
Bahaie N, Kang B, Frenzel E, Hosseinkhani M, Ge X, Greenberg Y, et al. N-Glycans differentially regulate eosinophil and neutrophil recruitment during allergic airway inflammation. J Biol Chem. 2011;286:38231-41 pubmed publisher
Cuervo H, Guerrero N, Carbajosa S, Beschin A, De Baetselier P, Girones N, et al. Myeloid-derived suppressor cells infiltrate the heart in acute Trypanosoma cruzi infection. J Immunol. 2011;187:2656-65 pubmed publisher
Verjan Garcia N, Umemoto E, Saito Y, Yamasaki M, Hata E, Matozaki T, et al. SIRP?/CD172a regulates eosinophil homeostasis. J Immunol. 2011;187:2268-77 pubmed publisher
Cain D, Snowden P, Sempowski G, Kelsoe G. Inflammation triggers emergency granulopoiesis through a density-dependent feedback mechanism. PLoS ONE. 2011;6:e19957 pubmed publisher
Yamada T, Tani Y, Nakanishi H, Taguchi R, Arita M, Arai H. Eosinophils promote resolution of acute peritonitis by producing proresolving mediators in mice. FASEB J. 2011;25:561-8 pubmed publisher
Shilling R, Clay B, Tesciuba A, Berry E, Lu T, Moore T, et al. CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo. Cell Immunol. 2009;259:177-84 pubmed publisher
Cannon J, Collins A, Mody P, Balachandran D, Henriksen K, Smith C, et al. CD43 regulates Th2 differentiation and inflammation. J Immunol. 2008;180:7385-93 pubmed
Gupta S, Fuchs B, Schulz Maronde S, Heitland A, Escher S, Mack M, et al. Intravascular inactivation of CCR5 by n-Nonanoyl-CC chemokine ligand 14 and inhibition of allergic airway inflammation. J Leukoc Biol. 2008;83:765-73 pubmed
Radinger M, Bossios A, Alm A, Jeurink P, Lu Y, Malmhall C, et al. Regulation of allergen-induced bone marrow eosinophilopoiesis: role of CD4+ and CD8+ T cells. Allergy. 2007;62:1410-8 pubmed
Ochkur S, Jacobsen E, Protheroe C, Biechele T, Pero R, McGarry M, et al. Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma. J Immunol. 2007;178:7879-89 pubmed
Fulkerson P, Fischetti C, McBride M, Hassman L, Hogan S, Rothenberg M. A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation. Proc Natl Acad Sci U S A. 2006;103:16418-23 pubmed
Munitz A, Bachelet I, Eliashar R, Khodoun M, Finkelman F, Rothenberg M, et al. CD48 is an allergen and IL-3-induced activation molecule on eosinophils. J Immunol. 2006;177:77-83 pubmed
product information
master code :
FAB729F
SKU :
FAB729F-025
product name :
Mouse CCR3 Fluorescein-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
description :
The Mouse CCR3 Fluorescein-conjugated Antibody from R&D Systems is a rat monoclonal antibody to CCR3. This antibody reacts with mouse. The Mouse CCR3 Fluorescein-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunocytochemistry.
target :
CCR3
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
83101
conjugate :
Fluorescein
host :
Rat
immunogen :
Y3 rat myeloid cell line transfected with mouse CCR3, Met1-Phe359, Accession # P51678
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CCR3. Specifically stains mouse CCR3 transfectants but not the parental cell lines. Does not cross-react with Y3 cells transfected with human CCR3.
gene symbol :
CCR3
top caption :
Detection of CCR3 antibody in Mouse Splenocytes antibody by Flow Cytometry.
accessionNumbers :
P51678
applications :
Flow Cytometry,Immunohistochemistry,Immunocytochemistry
USD :
139 USD
alt names :
b-chemokine receptor, CC chemokine receptor 3, C-C chemokine receptor type 3, C-C CKR-3, CCR3, CCR-3, CD193, CD193 antigen, chemokine (C-C motif) receptor 3, CKR3CC-CKR-3CMKBR3CD193, eosinophil CC chemokine receptor 3, Eosinophil eotaxin receptor, MGC102841
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.