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company name :
R&D Systems
product type :
antibody
product name :
Human B7-H6 PE-conjugated Antibody
catalog :
FAB7144P-025
quantity :
25 Tests (also 100 Tests)
price :
219 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
875001
reactivity :
human
application :
immunocytochemistry, flow cytometry, FACS
more info or order :
citations: 7
Reference
Lee S, Chae S, Jang I, Oh S, Kim S, Lee S, et al. B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies. EBioMedicine. 2024;110:105459 pubmed publisher
Pascual Pasto G, McIntyre B, Hines M, Giudice A, Garcia Gerique L, Hoffmann J, et al. CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma. Nat Commun. 2024;15:7141 pubmed publisher
Chimienti R, Baccega T, Torchio S, Manenti F, Pellegrini S, Cospito A, et al. Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for β cell replacement. Cell Rep. 2022;40:111423 pubmed publisher
Kim N, Kim M, Cho Y, Chen W, Lee K, Kim H. PVR and ICAM-1 on Blast Crisis CML Stem and Progenitor Cells with TKI Resistance Confer Susceptibility to NK Cells. Cancers (Basel). 2020;12: pubmed publisher
Suzuki D, Flahou C, Yoshikawa N, Stirblyte I, Hayashi Y, Sawaguchi A, et al. iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity. Stem Cell Reports. 2020;14:49-59 pubmed publisher
Truxova I, Kasikova L, Salek C, Hensler M, Lysak D, Holicek P, et al. Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients. Haematologica. 2020;105:1868-1878 pubmed publisher
Walwyn Brown K, Guldevall K, Saeed M, Pende D, Önfelt B, MacDonald A, et al. Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1. J Immunol. 2018;201:2028-2041 pubmed publisher
product information
master code :
FAB7144P
SKU :
FAB7144P-025
product name :
Human B7-H6 PE-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
description :
The Human B7-H6 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to B7-H6. This antibody reacts with human,mouse,transgenic mouse. The Human B7-H6 PE-conjugated Antibody has been validated for the following applications: FACS,Flow Cytometry,Immunocytochemistry,Knockout Validated.
target :
B7-H6
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
875001
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human B7-H6, Met1-Ser262, Accession # Q68D85
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects human B7-H6 in direct ELISAs.
gene symbol :
NCR3LG1
accessionNumbers :
Q68D85
applications :
FACS,Flow Cytometry,Immunocytochemistry,Knockout Validated
USD :
219 USD
alt names :
B7 homolog 6, B7H6, B7-H6, DKFZp686I21167, DKFZp686O24166, NCR3LG1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.