product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human B7-H6 APC-conjugated Antibody
catalog :
FAB7144A
quantity :
100 Tests
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
875001
reactivity :
human
application :
flow cytometry, FACS
more info or order :
citations: 8
Reference
Lee S, Chae S, Jang I, Oh S, Kim S, Lee S, et al. B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies. EBioMedicine. 2024;110:105459 pubmed publisher
Zhao N, Pi R, Nguyen D, Ranganath T, Seiler C, Holmes S, et al. NKp30 and NKG2D contribute to natural killer recognition of HIV-infected cells. bioRxiv. 2024;: pubmed publisher
Fisher J, Doyle A, Graham L, Sonar S, Sale B, Henderson I, et al. XPO1 inhibition sensitises CLL cells to NK cell mediated cytotoxicity and overcomes HLA-E expression. Leukemia. 2023;37:2036-2049 pubmed publisher
Shemesh A, Pickering H, Roybal K, Lanier L. Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion. J Exp Med. 2022;219: pubmed publisher
Gonz xe1 lez Ochoa S, Tellez Ba xf1 uelos M, M xe9 ndez Clemente A, Bravo Cuellar A, Hern xe1 ndez Flores G, Palafox Mariscal L, et al. Combination Blockade of the IL6R/STAT-3 Axis with TIGIT and Its Impact on the Functional Activity of NK Cells against Prostate Cancer Cells. J Immunol Res. 2022;2022:1810804 pubmed publisher
Aarsund M, Segers F, Wu Y, Inngjerdingen M. Comparison of characteristics and tumor targeting properties of extracellular vesicles derived from primary NK cells or NK-cell lines stimulated with IL-15 or IL-12/15/18. Cancer Immunol Immunother. 2022;71:2227-2238 pubmed publisher
Makanga D, Da Rin de Lorenzo F, David G, Willem C, Dubreuil L, Legrand N, et al. Genetic and Molecular Basis of Heterogeneous NK Cell Responses against Acute Leukemia. Cancers (Basel). 2020;12: pubmed publisher
Fasbender F, Obholzer M, Metzler S, St xf6 ber R, Hengstler J, Watzl C. Enhanced activation of human NK cells by drug-exposed hepatocytes. Arch Toxicol. 2020;94:439-448 pubmed publisher
product information
master code :
FAB7144A
SKU :
FAB7144A
product name :
Human B7-H6 APC-conjugated Antibody
unit size :
100 Tests
description :
The Human B7-H6 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to B7-H6. This antibody reacts with human. The Human B7-H6 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,FACS.
target :
B7-H6
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
875001
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human B7-H6, Met1-Ser262, Accession # Q68D85
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human B7-H6 in ELISAs.
gene symbol :
NCR3LG1
top caption :
Detection of B7-H6 antibody in HeLa Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
Q68D85
applications :
Flow Cytometry,FACS
USD :
459 USD
alt names :
B7 homolog 6, B7H6, B7-H6, DKFZp686I21167, DKFZp686O24166, NCR3LG1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.