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company name :
R&D Systems
product type :
antibody
product name :
Human CXCR6 PE-conjugated Antibody
catalog :
FAB699P-025
quantity :
25 Tests (also 100 Tests)
price :
159 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
56811
reactivity :
human, rhesus macaque
application :
immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 17
Reference
Fumagalli M, Lionetti M, Zapperi S, La Porta C. Cross-Talk Between circRNAs and mRNAs Modulates MiRNA-mediated Circuits and Affects Melanoma Plasticity. Cancer Microenviron. 2019;12:95-104 pubmed publisher
Lepore F, D Alessandro G, Antonangeli F, Santoro A, Esposito V, Limatola C, et al. CXCL16/CXCR6 Axis Drives Microglia/Macrophages Phenotype in Physiological Conditions and Plays a Crucial Role in Glioma. Front Immunol. 2018;9:2750 pubmed publisher
Hunter S, Willcox C, Davey M, Kasatskaya S, Jeffery H, Chudakov D, et al. Human liver infiltrating γδ T cells are composed of clonally expanded circulating and tissue-resident populations. J Hepatol. 2018;69:654-665 pubmed publisher
Koenen A, Babendreyer A, Schumacher J, Pasqualon T, Schwarz N, Seifert A, et al. The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion. PLoS ONE. 2017;12:e0173486 pubmed publisher
Faulkner L, Gibson A, Sullivan A, Tailor A, Usui T, Alfirevic A, et al. Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity. Toxicol Sci. 2016;154:416-429 pubmed
Hudspeth K, Donadon M, Cimino M, Pontarini E, Tentorio P, Preti M, et al. Human liver-resident CD56(bright)/CD16(neg) NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways. J Autoimmun. 2016;66:40-50 pubmed publisher
Shankar V, Hori H, Kihira K, Lei Q, Toyoda H, Iwamoto S, et al. Mesenchymal stromal cell secretome up-regulates 47 kDa CXCR4 expression, and induce invasiveness in neuroblastoma cell lines. PLoS ONE. 2015;10:e0120069 pubmed publisher
Lee W, Sanz M, Wong C, Hardy P, Salman Dilgimen A, Moriarty T, et al. Invariant natural killer T cells act as an extravascular cytotoxic barrier for joint-invading Lyme Borrelia. Proc Natl Acad Sci U S A. 2014;111:13936-41 pubmed publisher
Hu W, Liu Y, Zhou W, Si L, Ren L. CXCL16 and CXCR6 are coexpressed in human lung cancer in vivo and mediate the invasion of lung cancer cell lines in vitro. PLoS ONE. 2014;9:e99056 pubmed publisher
Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, et al. Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis. Clin Exp Immunol. 2011;163:215-24 pubmed publisher
Dusseaux M, Martin E, Serriari N, Peguillet I, Premel V, Louis D, et al. Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells. Blood. 2011;117:1250-9 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Campillo Gimenez L, Cumont M, Fay M, Kared H, Monceaux V, Diop O, et al. AIDS progression is associated with the emergence of IL-17-producing cells early after simian immunodeficiency virus infection. J Immunol. 2010;184:984-92 pubmed publisher
Gaida M, Gunther F, Wagner C, Friess H, Giese N, Schmidt J, et al. Expression of the CXCR6 on polymorphonuclear neutrophils in pancreatic carcinoma and in acute, localized bacterial infections. Clin Exp Immunol. 2008;154:216-23 pubmed publisher
Martini G, Cabrelle A, Calabrese F, Carraro S, Scquizzato E, Teramo A, et al. CXCR6-CXCL16 interaction in the pathogenesis of Juvenile Idiopathic Arthritis. Clin Immunol. 2008;129:268-76 pubmed publisher
Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, et al. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients. J Immunol. 2007;179:4272-82 pubmed
Freeman C, Curtis J, Chensue S. CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity. Am J Pathol. 2007;171:767-76 pubmed
product information
brand :
R&D Systems
master code :
FAB699P
SKU :
FAB699P-025
product name :
Human CXCR6 PE-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
seo description :
The Human CXCR6 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CXCR6. This antibody reacts with human,primate - macaca mulatta (rhesus macaque). The Human CXCR6 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunocytochemistry.
target :
CXCR6
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
56811
conjugate :
Phycoerythrin
dilution :
Flow Cytometry 10 uL/10^6 cells
host :
Mouse
immunogen :
NS0 mouse myeloma cell line transfected with human CXCR6, Met1-Leu342, Accession # O00574
isotype :
IgG2b
purity :
Protein A or G purified from ascites
species :
Human,Primate - Macaca mulatta (Rhesus Macaque)
specificity :
Stains human CXCR6 transfectants but not irrelevant transfectants.
gene symbol :
CXCR6
top caption :
Detection of CXCR6 antibody in Human PBMCs antibody by Flow Cytometry.
accessionNumbers :
O00574
applications :
Flow Cytometry,Immunohistochemistry,Immunocytochemistry
extended description :
Clone 56811 was used by HLDA to establish CD designation
USD :
159 USD
product details :
Clone 56811 was used by HLDA to establish CD designation
alt names :
Bonzo, BONZOG-protein coupled receptor bonzo, CD186, CD186 antigen, CDw186, chemokine (C-X-C motif) receptor 6, C-X-C chemokine receptor type 6, CXCR6, CXC-R6, CXCR-6, G protein-coupled receptor, STRL33, STRL33G-protein coupled receptor STRL33, TYMSTRCD186
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.