product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human GITR/TNFRSF18 PE-conjugated Antibody
catalog :
FAB689P-100
quantity :
100 Tests (also 25 Tests)
price :
379 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
110416
reactivity :
human
application :
flow cytometry
more info or order :
citations: 11
Reference
Ma X, Cao L, Raneri M, Wang H, Cao Q, Zhao Y, et al. Human HLA-DR+CD27+ regulatory T cells show enhanced antigen-specific suppressive function. JCI Insight. 2023;8: pubmed publisher
Cao L, Ma X, Zhang J, Yang M, He Z, Yang C, et al. CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response. Cell Transplant. 2023;32:9636897221149444 pubmed publisher
Kouakanou L, Peters C, Sun Q, Floess S, Bhat J, Huehn J, et al. Vitamin C supports conversion of human γδ T cells into FOXP3-expressing regulatory cells by epigenetic regulation. Sci Rep. 2020;10:6550 pubmed publisher
Lu Z, Xu N, Zhou X, Gao G, Li L, Huang J, et al. Therapeutic immune monitoring of CD4+CD25+ T cells in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors. Oncol Lett. 2017;14:1363-1372 pubmed publisher
Rodríguez Perea A, Montoya C, Olek S, Chougnet C, Velilla P. Statins increase the frequency of circulating CD4+ FOXP3+ regulatory T cells in healthy individuals. J Immunol Res. 2015;2015:762506 pubmed publisher
Lages C, Suffia I, Velilla P, Huang B, Warshaw G, Hildeman D, et al. Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation. J Immunol. 2008;181:1835-48 pubmed
Barboza L, Salmen S, Goncalves L, Colmenares M, Peterson D, Montes H, et al. Antigen-induced regulatory T cells in HBV chronically infected patients. Virology. 2007;368:41-9 pubmed
van der Vliet H, van der Vliet H, Koon H, Yue S, Uzunparmak B, Seery V, et al. Effects of the administration of high-dose interleukin-2 on immunoregulatory cell subsets in patients with advanced melanoma and renal cell cancer. Clin Cancer Res. 2007;13:2100-8 pubmed
Cavassani K, Campanelli A, Moreira A, Vancim J, Vitali L, Mamede R, et al. Systemic and local characterization of regulatory T cells in a chronic fungal infection in humans. J Immunol. 2006;177:5811-8 pubmed
Godfrey W, Spoden D, Ge Y, Baker S, Liu B, Levine B, et al. Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood. 2005;105:750-8 pubmed
Godfrey W, Ge Y, Spoden D, Levine B, June C, Blazar B, et al. In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures. Blood. 2004;104:453-61 pubmed
product information
master code :
FAB689P
SKU :
FAB689P-100
product name :
Human GITR/TNFRSF18 PE-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human GITR/TNFRSF18 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to GITR/TNFRSF18. This antibody reacts with human. The Human GITR/TNFRSF18 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
GITR/TNFRSF18
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
110416
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human GITR/TNFRSF18, Gln26-Glu161 (Thr43Ala), Accession # Q9Y5U5
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human GITR in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) 4-1BB, recombinant mouse (rm) 4-1BB, rhCD27, rmCD27, rhCD30, rmCD30, rhCD40, rmCD40, rhDR3, rhDR6, rhEDAR, rmEDAR, rhFas, rmFAS, rmGITR, rhHVEM, rhLymphotoxin R▀, rmLymphotoxin R▀, rhNGF R, rhOPG, rmOPG, rhRANK, rmRANK, rhTAJ, rhTNF RI, rmTNF RI, rhTNF RII, or rmTNF RII.
gene symbol :
TNFRSF18
top caption :
Detection of GITR/TNFRSF18 antibody in Human PBMCs antibody by Flow Cytometry.
accessionNumbers :
Q9Y5U5
applications :
Flow Cytometry
USD :
379 USD
alt names :
Activation-inducible TNFR family receptor, AITR, AITRTNF receptor superfamily activation-inducible protein, CD357, CD357 antigen, GITR-D, GITRtumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein, TNFRSF18, tumor necrosis factor receptor superfamily, member 18
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.