product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human GITR/TNFRSF18 APC-conjugated Antibody
catalog :
FAB689A-100
quantity :
100 Tests (also 25 Tests)
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
110416
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 4
Reference
Heninger A, Theil A, Wilhelm C, Petzold C, Huebel N, Kretschmer K, et al. IL-7 abrogates suppressive activity of human CD4+CD25+FOXP3+ regulatory T cells and allows expansion of alloreactive and autoreactive T cells. J Immunol. 2012;189:5649-58 pubmed publisher
Perez S, Karamouzis M, Skarlos D, Ardavanis A, Sotiriadou N, Iliopoulou E, et al. CD4+CD25+ regulatory T-cell frequency in HER-2/neu (HER)-positive and HER-negative advanced-stage breast cancer patients. Clin Cancer Res. 2007;13:2714-21 pubmed
Tuyaerts S, Van Meirvenne S, Bonehill A, Heirman C, Corthals J, Waldmann H, et al. Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells. J Leukoc Biol. 2007;82:93-105 pubmed
Yang X, Yamagiwa S, Ichida T, Matsuda Y, Sugahara S, Watanabe H, et al. Increase of CD4+ CD25+ regulatory T-cells in the liver of patients with hepatocellular carcinoma. J Hepatol. 2006;45:254-62 pubmed
product information
master code :
FAB689A
SKU :
FAB689A-100
product name :
Human GITR/TNFRSF18 APC-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human GITR/TNFRSF18 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to GITR/TNFRSF18. This antibody reacts with human. The Human GITR/TNFRSF18 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
GITR/TNFRSF18
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
110416
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human GITR/TNFRSF18, Gln26-Glu161 (Thr43Ala), Accession # Q9Y5U5
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human GITR in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) 4-1BB, recombinant mouse (rm) 4-1BB, rhCD27, rmCD27, rhCD30, rmCD30, rhCD40, rmCD40, rhDR3, rhDR6, rhEDAR, rmEDAR, rhFas, rmFAS, rmGITR, rhHVEM, rhLymphotoxin R▀, rmLymphotoxin R▀, rhNGF R, rhOPG, rmOPG, rhRANK, rmRANK, rhTAJ, rhTNF RI, rmTNF RI, rhTNF RII, or rmTNF RII.
gene symbol :
TNFRSF18
top caption :
Detection of GITR/TNFRSF18 antibody in Human Blood CD4+Lymphocytes antibody by Flow Cytometry.
accessionNumbers :
Q9Y5U5
applications :
Flow Cytometry
USD :
439 USD
alt names :
Activation-inducible TNFR family receptor, AITR, AITRTNF receptor superfamily activation-inducible protein, CD357, CD357 antigen, GITR-D, GITRtumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein, TNFRSF18, tumor necrosis factor receptor superfamily, member 18
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.