product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-1 RAcP/IL-1 R3 PE-conjugated Antibody
catalog :
FAB676P
quantity :
100 Tests
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
89412
reactivity :
human
application :
flow cytometry
more info or order :
citations: 5
Reference
Rai S, Grockowiak E, Hansen N, Luque Paz D, Stoll C, Hao Shen H, et al. Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm. Nat Commun. 2022;13:5346 pubmed publisher
Cruz J, Mokashi C, Kowalczyk G, Guo Y, Zhang Q, Gupta S, et al. A variable-gain stochastic pooling motif mediates information transfer from receptor assemblies into NF-κB. Sci Adv. 2021;7: pubmed publisher
Zhang H, Hughes C, Li W, He J, Surdez D, El Naggar A, et al. Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma. Cancer Discov. 2021;11:2884-2903 pubmed publisher
Eldesouki R, Wu C, Saleh F, Mohammed E, Younes S, Hassan N, et al. Identification and Targeting of Thomsen-Friedenreich and IL1RAP Antigens on Chronic Myeloid Leukemia Stem Cells Using Bi-Specific Antibodies. Onco Targets Ther. 2021;14:609-621 pubmed publisher
Zhang B, Chu S, Agarwal P, Campbell V, Hopcroft L, J xf8 rgensen H, et al. Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor-treated CML stem cells. Blood. 2016;128:2671-2682 pubmed
product information
master code :
FAB676P
SKU :
FAB676P
product name :
Human IL-1 RAcP/IL-1 R3 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human IL-1 RAcP/IL-1 R3 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IL-1 RAcP/IL-1 R3. This antibody reacts with human. The Human IL-1 RAcP/IL-1 R3 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
IL-1 RAcP/IL-1 R3
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
89412
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-1RAcP/IL-1 R3, Ser21-Glu359 (predicted), Accession # Q9NPH3
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human IL-1RAcP/IL-1 R3 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-1 RI, rhIL-1 RII, rhST2, rhIL-18 R alpha , IL-1 Rrp2, rhIL-18 RAP, rhSIGIRR, rhIL-1 RAPL1, rhIL-1 RAPL2, rhTLR1, rhTLR2, rhTLR3, rhTLR4, rhTLR5, rhTLR7, rhTLR8, rhTLR9, rhTLR10, rhMD-1, rhMD-2, or recombinant mouse RP105 is observed.
gene symbol :
IL1RAP
top caption :
Detection of IL-1 RAcP/IL-1 R3 antibody in Human Monocytes antibody by Flow Cytometry.
accessionNumbers :
Q9NPH3
applications :
Flow Cytometry
USD :
439 USD
alt names :
C3orf13IL-1RAcPIL1R3Interleukin-1 receptor 3, FLJ37788, IL-1 R3, IL-1 receptor accessory protein, IL-1R3, IL-1R-3, IL1RAcP, IL-1RAcP, IL1RAP, interleukin 1 receptor accessory protein, interleukin-1 receptor accessory protein, interleukin-1 receptor accessory protein beta
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.