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company name :
R&D Systems
product type :
antibody
product name :
Human ALCAM/CD166 PE-conjugated Antibody
catalog :
FAB6561P
quantity :
100 Tests
price :
379 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
105902
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 18
Reference
Chun Y, Tan K, Yu L, Pang M, Wong M, Nakamoto R, et al. Influence of glycan structure on the colonization of Streptococcus pneumoniae on human respiratory epithelial cells. Proc Natl Acad Sci U S A. 2023;120:e2213584120 pubmed publisher
Yoshida H, Koodie L, Jacobsen K, Hanzawa K, Miyamoto Y, Yamamoto M. B4GALNT1 induces angiogenesis, anchorage independence growth and motility, and promotes tumorigenesis in melanoma by induction of ganglioside GM2/GD2. Sci Rep. 2020;10:1199 pubmed publisher
Mount S, Kanda P, Parent S, Khan S, Michie C, Davila L, et al. Physiologic expansion of human heart-derived cells enhances therapeutic repair of injured myocardium. Stem Cell Res Ther. 2019;10:316 pubmed publisher
Essex A, Pineda J, Acharya G, Xin H, Evans J, Iorns E, et al. Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. elife. 2019;8: pubmed publisher
Wang Z, Yip L, Lee J, Wu Z, Chew H, Chong P, et al. Methionine is a metabolic dependency of tumor-initiating cells. Nat Med. 2019;: pubmed publisher
Bogachek M, Park J, De Andrade J, Lorenzen A, Kulak M, White J, et al. Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas. Stem Cell Reports. 2016;7:1140-1151 pubmed publisher
Liu D, Du L, Chen D, Ye Z, Duan H, Tu T, et al. Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/?-catenin signaling. Oncotarget. 2016;7:40704-40718 pubmed publisher
Evans J, Essex A, Xin H, Amitai N, Brinton L, Griner E. Registered report: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. elife. 2015;4: pubmed publisher
Fujiwara K, Ohuchida K, Sada M, Horioka K, Ulrich C, Shindo K, et al. CD166/ALCAM expression is characteristic of tumorigenicity and invasive and migratory activities of pancreatic cancer cells. PLoS ONE. 2014;9:e107247 pubmed publisher
Rowehl R, Burke S, Bialkowska A, Pettet D, Rowehl L, Li E, et al. Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells. PLoS ONE. 2014;9:e99091 pubmed publisher
Tachezy M, Zander H, Wolters Eisfeld G, Muller J, Wicklein D, Gebauer F, et al. Activated leukocyte cell adhesion molecule (CD166): an "inert" cancer stem cell marker for non-small cell lung cancer?. Stem Cells. 2014;32:1429-36 pubmed publisher
Mirkina I, Hadzijusufovic E, Krepler C, Mikula M, Mechtcheriakova D, Strommer S, et al. Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R. PLoS ONE. 2014;9:e84417 pubmed publisher
Kalaszczynska I, Ruminski S, Platek A, Bissenik I, Zakrzewski P, Noszczyk M, et al. Substantial differences between human and ovine mesenchymal stem cells in response to osteogenic media: how to explain and how to manage?. Biores Open Access. 2013;2:356-63 pubmed publisher
Albert R, Veréb Z, Csomós K, Moe M, Johnsen E, Olstad O, et al. Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium. PLoS ONE. 2012;7:e47187 pubmed publisher
Soh B, Zheng D, Li Yeo J, Yang H, Ng S, Wong L, et al. CD166(pos) subpopulation from differentiated human ES and iPS cells support repair of acute lung injury. Mol Ther. 2012;20:2335-46 pubmed publisher
Kondo S, Wakisaka N, Muramatsu M, Zen Y, Endo K, Murono S, et al. Epstein-Barr virus latent membrane protein 1 induces cancer stem/progenitor-like cells in nasopharyngeal epithelial cell lines. J Virol. 2011;85:11255-64 pubmed publisher
Giuliani M, Fleury M, Vernochet A, Ketroussi F, Clay D, Azzarone B, et al. Long-lasting inhibitory effects of fetal liver mesenchymal stem cells on T-lymphocyte proliferation. PLoS ONE. 2011;6:e19988 pubmed publisher
Firth A, Yao W, Ogawa A, Madani M, Lin G, Yuan J. Multipotent mesenchymal progenitor cells are present in endarterectomized tissues from patients with chronic thromboembolic pulmonary hypertension. Am J Physiol Cell Physiol. 2010;298:C1217-25 pubmed publisher
product information
master code :
FAB6561P
SKU :
FAB6561P
product name :
Human ALCAM/CD166 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human ALCAM/CD166 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to ALCAM/CD166. This antibody reacts with human. The Human ALCAM/CD166 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Cell Selection,Immunocytochemistry.
target :
ALCAM/CD166
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
105902
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human ALCAM/CD166, Trp28-Ala526, Accession # Q13740
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human ALCAM in Western blots. Shows approximately 50% cross-reactivity with recombinant mouse OCAM and no cross-reactivity with recombinant human (rh) BCAM, rhEpCAM, rhMCAM, or rhNCAM-L1.
gene symbol :
ALCAM
top caption :
Detection of ALCAM/CD166 antibody in Human Whole Blood Monocytes antibody by Flow Cytometry.
accessionNumbers :
Q13740
applications :
Flow Cytometry,Cell Selection,Immunocytochemistry
USD :
379 USD
alt names :
activated leucocyte cell adhesion molecule, activated leukocyte cell adhesion moleculeFLJ38514, CD166, CD166 antigen, MEMDMGC71733
storage :
Store the unopened product at 2 - 8░ C. Do not use past expiration date. Protect from light.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.