Human TROP-2 APC-conjugated Antibody | R&D Systems FAB650A product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TROP-2 APC-conjugated Antibody

catalog :

FAB650A

quantity :

100 Tests

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

77220

reactivity :

human, mouse

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Hussain S, Lawrence M, Taylor R, Lo C, Frydenberg M, Ellem S, et al. Estrogen receptor ? activation impairs prostatic regeneration by inducing apoptosis in murine and human stem/progenitor enriched cell populations. PLoS ONE. 2012;7:e40732 pubmed publisher
flow cytometry; mouse	Goldstein A, Huang J, Guo C, Garraway I, Witte O. Identification of a cell of origin for human prostate cancer. Science. 2010;329:568-71 pubmed publisher
	x160 vec J, x160 x165 astn xe1 M, Jane x10d kov xe1 L, Hr x10d kul xe1 k D, Vojt x11b chov xe1 M, Onhajzer J, et al. TROP2 Represents a Negative Prognostic Factor in Colorectal Adenocarcinoma and Its Expression Is Associated with Features of Epithelial-Mesenchymal Transition and Invasiveness. Cancers (Basel). 2022;14: pubmed publisher
	Len xe1 rt S, Len xe1 rt P, Knopfov xe1 L, Kotasov xe1 H, Pelkov xe1 V, Sedl xe1 kov xe1 V, et al. TACSTD2 upregulation is an early reaction to lung infection. Sci Rep. 2022;12:9583 pubmed publisher
	Park J, Lee J, Phillips J, Huang P, Cheng D, Huang J, et al. Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay. Proc Natl Acad Sci U S A. 2016;113:4482-7 pubmed publisher
	Smith D, Kiba A, Zong Y, Witte O. Interleukin-6 and oncostatin-M synergize with the PI3K/AKT pathway to promote aggressive prostate malignancy in mouse and human tissues. Mol Cancer Res. 2013;11:1159-65 pubmed publisher
	Goldstein A, Drake J, Burnes D, Finley D, Zhang H, Reiter R, et al. Purification and direct transformation of epithelial progenitor cells from primary human prostate. Nat Protoc. 2011;6:656-67 pubmed publisher

product information

master code :

FAB650A

SKU :

FAB650A

product name :

Human TROP-2 APC-conjugated Antibody

unit size :

100 Tests

description :

The Human TROP-2 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to TROP-2. This antibody reacts with human. The Human TROP-2 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

TROP-2

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

77220

conjugate :

Allophycocyanin

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TROP-2, His27-Thr274, Accession # P09758

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human TROP-2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) VCAM-1 or rhICAM-1 is observed.

gene symbol :

TACSTD2

top caption :

Detection of TROP-2 antibody in PC-3 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

P09758

applications :

Flow Cytometry

USD :

489 USD

alt names :

Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, gp50, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, T16, TACSTD2, TROP2, TROP2GA7331, tumor-associated calcium signal transducer 2

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage