product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TRAILR4/TNFRSF10D PE-conjugated Antibody
catalog :
FAB633P
quantity :
100 Tests
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
104918
reactivity :
human
application :
flow cytometry
more info or order :
citations: 20
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig st1
Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  • flow cytometry; human
Kim S, Woo J, Jeong C, Ryu C, Jang J, Jeun S. Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma. Stem Cells Transl Med. 2014;3:172-82 pubmed publisher
  • flow cytometry; human
Kalb M, Glaser A, Stary G, Koszik F, Stingl G. TRAIL(+) human plasmacytoid dendritic cells kill tumor cells in vitro: mechanisms of imiquimod- and IFN-?-mediated antitumor reactivity. J Immunol. 2012;188:1583-91 pubmed publisher
  • flow cytometry; human
Stary G, Klein I, Kohlhofer S, Koszik F, Scherzer T, Müllauer L, et al. Plasmacytoid dendritic cells express TRAIL and induce CD4+ T-cell apoptosis in HIV-1 viremic patients. Blood. 2009;114:3854-63 pubmed publisher
  • flow cytometry; human
Secchiero P, Melloni E, Corallini F, Beltrami A, Alviano F, Milani D, et al. Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells. Stem Cells. 2008;26:2955-63 pubmed publisher
  • flow cytometry; human
Dunn C, Brunetto M, Reynolds G, Christophides T, Kennedy P, Lampertico P, et al. Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage. J Exp Med. 2007;204:667-80 pubmed
Greenlee J, Lopez Cavestany M, Ortiz Otero N, Liu K, Subramanian T, Cagir B, et al. Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization. elife. 2021;10: pubmed publisher
Ren Y, Wang X, Huang S, Xu Y, Weng G, Yu R. Alternol Sensitizes Renal Carcinoma Cells to TRAIL-Induced Apoptosis. Front Pharmacol. 2021;12:560903 pubmed publisher
Madsen S, Jones S, Tucker H, Giler M, Muller D, Discher C, et al. Survival of aging CD264+ and CD264- populations of human bone marrow mesenchymal stem cells is independent of colony-forming efficiency. Biotechnol Bioeng. 2020;117:223-237 pubmed publisher
Jo E, Lee Y, Lee H, Park J, Park H, Choi Y, et al. Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells. BMC Cancer. 2019;19:496 pubmed publisher
Madsen S, Russell K, Tucker H, Glowacki J, Bunnell B, O Connor K. Decoy TRAIL receptor CD264: a cell surface marker of cellular aging for human bone marrow-derived mesenchymal stem cells. Stem Cell Res Ther. 2017;8:201 pubmed publisher
Jaworska D, Szliszka E. Targeting Apoptotic Activity Against Prostate Cancer Stem Cells. Int J Mol Sci. 2017;18: pubmed publisher
Singh H, Otano I, Rombouts K, Singh K, Peppa D, Gill U, et al. TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis. Sci Rep. 2017;7:5514 pubmed publisher
Zauli G, Celeghini C, Monasta L, Martinelli M, Luppi S, Gonelli A, et al. Soluble TRAIL is present at high concentrations in seminal plasma and promotes spermatozoa survival. Reproduction. 2014;148:191-8 pubmed publisher
Tang X, Lu J, Tu H, Huang K, Fu R, Cao G, et al. TRAIL-engineered bone marrow-derived mesenchymal stem cells: TRAIL expression and cytotoxic effects on C6 glioma cells. Anticancer Res. 2014;34:729-34 pubmed
Trebing J, El Mesery M, Schafer V, Weisenberger D, Siegmund D, Silence K, et al. CD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants. Cell Death Dis. 2014;5:e1035 pubmed publisher
Walsh C, Luer C, Yordy J, Cantu T, Miedema J, Leggett S, et al. Epigonal conditioned media from bonnethead shark, Sphyrna tiburo, induces apoptosis in a T-cell leukemia cell line, Jurkat E6-1. Mar Drugs. 2013;11:3224-57 pubmed publisher
Gojo I, Tan M, Fang H, Sadowska M, Lapidus R, Baer M, et al. Translational phase I trial of vorinostat (suberoylanilide hydroxamic acid) combined with cytarabine and etoposide in patients with relapsed, refractory, or high-risk acute myeloid leukemia. Clin Cancer Res. 2013;19:1838-51 pubmed publisher
Zhang B, Shan H, Li D, Li Z, Zhu K, Jiang Z, et al. Cisplatin sensitizes human hepatocellular carcinoma cells, but not hepatocytes and mesenchymal stem cells, to TRAIL within a therapeutic window partially depending on the upregulation of DR5. Oncol Rep. 2011;25:461-8 pubmed publisher
Kim S, Lim J, Park S, Jeong C, Oh J, Jeong M, et al. Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial glioma. Cancer Res. 2008;68:9614-23 pubmed publisher
product information
master code :
FAB633P
SKU :
FAB633P
product name :
Human TRAILR4/TNFRSF10D PE-conjugated Antibody
unit size :
100 Tests
description :
The Human TRAILR4/TNFRSF10D PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to TRAILR4/TNFRSF10D/DcR2. This antibody reacts with human,rat. The Human TRAILR4/TNFRSF10D PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
TRAILR4/TNFRSF10D
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
104918
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human TRAIL R4/TNFRSF10D, Ala56-His211, Accession # Q9UBN6
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human,Rat
specificity :
Detects human TRAIL R4/TNFRSF10D in ELISAs and Western blots. In sandwich immunoassays, less than 5% cross-reactivity with recombinant human (rh) TRAIL R1, rhTRAIL R2, TRAIL R3, rhTRAIL, rhTNF-alpha , and rhTNF┐▀ is observed.
gene symbol :
TNFRSF10D
top caption :
Detection of TRAIL R4/TNFRSF10D antibody in Human Blood Granulocytes antibody by Flow Cytometry.
accessionNumbers :
Q9UBN6
applications :
Flow Cytometry
USD :
439 USD
alt names :
CD264, CD264 antigen, DcR2, DCR2decoy with truncated death domain, Decoy receptor 2, TNF receptor-related receptor for TRAIL, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL R4, TRAIL-R4, TRAILR4TRAIL receptor 4, TRUNDDTRAIL receptor with a truncated death domain, tumor necrosis factor receptor superfamily member 10D, tumor necrosis factor receptor superfamily, member 10d, decoy with truncateddeath domain
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.