product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TRAIL R2/TNFRSF10B APC-conjugated Antibody
catalog :
FAB6311A-100
quantity :
100 Tests (also 25 Tests)
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
71908
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 5
Reference
Hagelund S, Trauzold A. Impact of Extracellular pH on Apoptotic and Non-Apoptotic TRAIL-Induced Signaling in Pancreatic Ductal Adenocarcinoma Cells. Front Cell Dev Biol. 2022;10:768579 pubmed publisher
Fakiruddin K, Lim M, Nordin N, Rosli R, Zakaria Z, Abdullah S. Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer. Cancers (Basel). 2019;11: pubmed publisher
Mert U, Adawy A, Scharff E, Teichmann P, Willms A, Haselmann V, et al. TRAIL Induces Nuclear Translocation and Chromatin Localization of TRAIL Death Receptors. Cancers (Basel). 2019;11: pubmed publisher
Willms A, Schittek H, Rahn S, Sosna J, Mert U, Adam D, et al. Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells. PLoS ONE. 2019;14:e0214847 pubmed publisher
Meng X, Koh B, Zhang J, Flatten K, Schneider P, Billadeau D, et al. Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression. J Biol Chem. 2014;289:20543-58 pubmed
product information
master code :
FAB6311A
SKU :
FAB6311A-100
product name :
Human TRAIL R2/TNFRSF10B APC-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human TRAIL R2/TNFRSF10B APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to TRAILR2/TNFRSF10B. This antibody reacts with human. The Human TRAIL R2/TNFRSF10B APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
TRAIL R2/TNFRSF10B
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
71908
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human TRAIL R2/TNFRSF10B, Ile56-Glu182, Accession # O14763
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human TRAIL R2 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) TRAIL R1, rhTRAIL R3, rhTRAIL R4, or recombinant mouse TRAIL R2.
gene symbol :
TNFRSF10B
top caption :
Detection of TRAIL R2/TNFRSF10B antibody in MDA-MB-231 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
O14763
applications :
Flow Cytometry
USD :
439 USD
alt names :
CD262, CD262 antigen, death domain containing receptor for TRAIL/Apo-2L, Death receptor 5, DR5, DR5TRICK2B, Fas-like protein, KILLER/DR5, KILLERapoptosis inducing protein TRICK2A/2B, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAILR2, TRAIL-R2apoptosis inducing receptor TRAIL-R2, TRAILR2cytotoxic TRAIL receptor-2, TRICK2, TRICK2A, TRICKB, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9, ZTNFR9
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.