product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse CCR6 PE-conjugated Antibody
catalog :
FAB590P-025
quantity :
25 Tests (also 100 Tests)
price :
179 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
140706
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 20
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 4e
Shi Z, Takeuchi T, Nakanishi Y, Kato T, Beck K, Nagata R, et al. A Japanese Herbal Formula, Daikenchuto, Alleviates Experimental Colitis by Reshaping Microbial Profiles and Enhancing Group 3 Innate Lymphoid Cells. Front Immunol. 2022;13:903459 pubmed publisher
Chen S, Oliveira T, Gazumyan A, Cipolla M, Nussenzweig M. B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection. Immunity. 2023;56:547-561.e7 pubmed publisher
Oishi K, Horiuchi S, Frere J, Schwartz R, tenOever B. A diminished immune response underlies age-related SARS-CoV-2 pathologies. Cell Rep. 2022;39:111002 pubmed publisher
B xe4 uerlein C, Qureischi M, Mokhtari Z, Tabares P, Brede C, Jord xe1 n Garrote A, et al. A T-Cell Surface Marker Panel Predicts Murine Acute Graft-Versus-Host Disease. Front Immunol. 2020;11:593321 pubmed publisher
Picard M, Yonekura S, Slowicka K, Petta I, Rauber C, Routy B, et al. Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients. Cell Death Differ. 2021;28:1532-1547 pubmed publisher
Yamamoto T, Endo Y, Onodera A, Hirahara K, Asou H, Nakajima T, et al. DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells. Nat Commun. 2018;9:4231 pubmed publisher
Emgård J, Kammoun H, García Cassani B, Chesne J, Parigi S, Jacob J, et al. Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation. Immunity. 2018;48:120-132.e8 pubmed publisher
Boyle S, Faulkner J, McColl S, Kochetkova M. The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages. Mol Cancer. 2015;14:115 pubmed publisher
Badr G, Sayed A, Abdel Maksoud M, Mohamed A, El Amir A, Abdel Ghaffar F, et al. Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFκB and ERK. PLoS ONE. 2015;10:e0125340 pubmed publisher
Angkasekwinai P, Sringkarin N, Supasorn O, Fungkrajai M, Wang Y, Chayakulkeeree M, et al. Cryptococcus gattii infection dampens Th1 and Th17 responses by attenuating dendritic cell function and pulmonary chemokine expression in the immunocompetent hosts. Infect Immun. 2014;82:3880-90 pubmed publisher
Cai Y, Xue F, Fleming C, Yang J, Ding C, Ma Y, et al. Differential developmental requirement and peripheral regulation for dermal V?4 and V?6T17 cells in health and inflammation. Nat Commun. 2014;5:3986 pubmed publisher
Klein M, Brouwer M, Angele B, Geldhoff M, Marquez G, Varona R, et al. Leukocyte attraction by CCL20 and its receptor CCR6 in humans and mice with pneumococcal meningitis. PLoS ONE. 2014;9:e93057 pubmed publisher
Peng H, Jiang X, Chen Y, Sojka D, Wei H, Gao X, et al. Liver-resident NK cells confer adaptive immunity in skin-contact inflammation. J Clin Invest. 2013;123:1444-56 pubmed publisher
Cherrier M, Sawa S, Eberl G. Notch, Id2, and ROR?t sequentially orchestrate the fetal development of lymphoid tissue inducer cells. J Exp Med. 2012;209:729-40 pubmed publisher
Alcaide P, Maganto Garcia E, Newton G, Travers R, CROCE K, Bu D, et al. Difference in Th1 and Th17 lymphocyte adhesion to endothelium. J Immunol. 2012;188:1421-30 pubmed publisher
Song J, Kim J, Kwon H, Shim D, Parajuli N, Cuburu N, et al. CCR7-CCL19/CCL21-regulated dendritic cells are responsible for effectiveness of sublingual vaccination. J Immunol. 2009;182:6851-60 pubmed publisher
Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, Onoue M, et al. ATP drives lamina propria T(H)17 cell differentiation. Nature. 2008;455:808-12 pubmed publisher
Cox C, Shi G, Yin H, Vistica B, Wawrousek E, Chan C, et al. Both Th1 and Th17 are immunopathogenic but differ in other key biological activities. J Immunol. 2008;180:7414-22 pubmed
Calderon B, Suri A, Miller M, Unanue E. Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules. Proc Natl Acad Sci U S A. 2008;105:6121-6 pubmed publisher
Robays L, Maes T, Lebecque S, Lira S, Kuziel W, Brusselle G, et al. Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation. J Immunol. 2007;178:5305-11 pubmed
product information
master code :
FAB590P
SKU :
FAB590P-025
product name :
Human/Mouse CCR6 PE-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
description :
The Human/Mouse CCR6 PE-conjugated Antibody from R&D Systems is a rat monoclonal antibody to CCR6. This antibody reacts with hamster,human,mouse,transgenic mouse. The Human/Mouse CCR6 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry.
target :
CCR6
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
140706
conjugate :
Phycoerythrin
host :
Rat
immunogen :
RBL-1 rat basophilic leukemia cell line transfected with mouse CCR6, Met1-Met367, Accession # O54689
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Hamster,Human,Mouse
specificity :
Detects mouse CCR6-transfected rat RBL cells but not the parent cell line or cells transfected with mouse CCR5. Detects human CCR6 in flow cytometry.
gene symbol :
CCR6
top caption :
Detection of CCR6 antibody in Mouse Splenocytes antibody by Flow Cytometry.
accessionNumbers :
O54689
applications :
Flow Cytometry,Immunocytochemistry
USD :
179 USD
alt names :
BN-1, CC-CKR-6, CCR6, CCR-6, CD196, CD196 antigen, chemokine (C-C motif) receptor 6, CKRL3, CKR-L3, CKR-L3G-protein coupled receptor 29, CKRL3LARC receptor, CMKBR6, CMKBR6STRL22, DRY6, GPR29, GPR29C-C CKR-6, GPRCY4, GPR-CY4, GPRCY4DRY-6, lymphocyte, 22, STRL22
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.