product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CCR2 Fluorescein-conjugated Antibody
catalog :
FAB5538F-025
quantity :
25 Tests (also 100 Tests)
price :
159 USD
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
475301
reactivity :
human, mouse
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 18
Reference
Boddupalli C, Nair S, Belinsky G, GANS J, Teeple E, Nguyen T, et al. Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy. elife. 2022;11: pubmed publisher
Hamid T, Xu Y, Ismahil M, Rokosh G, Jinno M, Zhou G, et al. Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling. JACC Basic Transl Sci. 2022;7:465-483 pubmed publisher
Dá Mesquita S, Herz J, Wall M, Dykstra T, de Lima K, Norris G, et al. Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology. Sci Adv. 2021;7: pubmed publisher
Dá Mesquita S, Papadopoulos Z, Dykstra T, Brase L, Farias F, Wall M, et al. Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy. Nature. 2021;: pubmed publisher
Youssif C, Cubillos Rojas M, Comalada M, Llonch E, Perna C, Djouder N, et al. Myeloid p38α signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis. EMBO Mol Med. 2018;10: pubmed publisher
Kaneko Y, Cho T, Sato Y, Goto K, Yamamoto S, Goto S, et al. Attenuated Macrophage Infiltration in Glomeruli of Aged Mice Resulting in Ameliorated Kidney Injury in Nephrotoxic Serum Nephritis. J Gerontol A Biol Sci Med Sci. 2018;73:1178-1186 pubmed publisher
Kaufmann E, Sanz J, Dunn J, Khan N, Mendonça L, Pacis A, et al. BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis. Cell. 2018;172:176-190.e19 pubmed publisher
Wu X, Dayanand K, Thylur R, Norbury C, Gowda D. Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes. J Biol Chem. 2017;292:13615-13634 pubmed publisher
Guerra E, Lee C, Specht C, Yadav B, Huang H, Akalin A, et al. Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma. PLoS Pathog. 2017;13:e1006175 pubmed publisher
Chow K, Delconte R, Huntington N, Tarlinton D, Sutherland R, Zhan Y, et al. Innate Allorecognition Results in Rapid Accumulation of Monocyte-Derived Dendritic Cells. J Immunol. 2016;197:2000-8 pubmed publisher
Wattananit S, Tornero D, Graubardt N, Memanishvili T, Monni E, Tatarishvili J, et al. Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice. J Neurosci. 2016;36:4182-95 pubmed publisher
Levy N, Milikovsky D, Baranauskas G, Vinogradov E, David Y, Ketzef M, et al. Differential TGF-β Signaling in Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice. J Immunol. 2015;195:1713-22 pubmed publisher
Viana I, de Almeida M, Lins M, Dos Santos Reis M, de Araújo Vieira L, Smaniotto S. Combined effect of insulin-like growth factor-1 and CC chemokine ligand 2 on angiogenic events in endothelial cells. PLoS ONE. 2015;10:e0121249 pubmed publisher
Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, et al. Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Nature. 2014;515:130-3 pubmed publisher
Neal L, Knoll L. Toxoplasma gondii profilin promotes recruitment of Ly6Chi CCR2+ inflammatory monocytes that can confer resistance to bacterial infection. PLoS Pathog. 2014;10:e1004203 pubmed publisher
Nie P, Li D, Hu L, Jin S, Yu Y, Cai Z, et al. Atorvastatin improves plaque stability in ApoE-knockout mice by regulating chemokines and chemokine receptors. PLoS ONE. 2014;9:e97009 pubmed publisher
Heim C, Vidlak D, Scherr T, Kozel J, Holzapfel M, Muirhead D, et al. Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection. J Immunol. 2014;192:3778-92 pubmed publisher
Simons D, Oh S, Kropf E, Aitken M, Garcia V, Basehoar A, et al. Autoreactive Th1 cells activate monocytes to support regional Th17 responses in inflammatory arthritis. J Immunol. 2013;190:3134-41 pubmed publisher
product information
brand :
R&D Systems
master code :
FAB5538F
SKU :
FAB5538F-025
product name :
Mouse CCR2 Fluorescein-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
seo description :
The Mouse CCR2 Fluorescein-conjugated Antibody from R&D Systems is a rat monoclonal antibody to CCR2. This antibody reacts with mouse. The Mouse CCR2 Fluorescein-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
CCR2
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
475301
conjugate :
Fluorescein
dilution :
Flow Cytometry 10 uL/10^6 cells
host :
Rat
immunogen :
L1.2 mouse pro-B cell line transfected with mouse CCR2
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CCR2 transfectants but not the parental cell line in flow cytometry. Does not detect HEK293 human embryonic kidney cell line transfected with mouse CCR5 in flow cytometry.
gene symbol :
CCR2
top caption :
Detection of CCR2 antibody in Mouse Splenocytes antibody by Flow Cytometry.
applications :
Flow Cytometry
USD :
159 USD
alt names :
C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CC-CKR-2CKR2B, CCR2, CCR-2, CCR2A, CCR2B, CD192, CD192 antigen, chemokine (C-C motif) receptor 2, CKR2, CKR2A, CMKBR2, CMKBR2MGC111760, FLJ78302, MCP-1 receptor, MCP-1-R, MCP-1-RMGC103828, MGC168006, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.