product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse TGF┐▀ RII PE-conjugated Antibody
catalog :
FAB532P-100UG
quantity :
100 ug (also 25 ug)
price :
379 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
PE
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 11
Reference
Barnkob M, Michaels Y, Andr xe9 V, Macklin P, Gileadi U, Valvo S, et al. Semmaphorin 3 A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells. Nat Commun. 2024;15:3173 pubmed publisher
Gu C, Liu Y, Lv J, Zhang C, Huang Z, Jiang Q, et al. Kurarinone regulates Th17/Treg balance and ameliorates autoimmune uveitis via Rac1 inhibition. J Adv Res. 2024;: pubmed publisher
Liu X, Gu C, Lv J, Jiang Q, Ding W, Huang Z, et al. Progesterone attenuates Th17-cell pathogenicity in autoimmune uveitis via Id2/Pim1 axis. J Neuroinflammation. 2023;20:144 pubmed publisher
Zeboudj L, Sideris Lampretsas G, Silva R, Al Mudaris S, Picco F, Fox S, et al. Silencing miR-21-5p in sensory neurons reverses neuropathic allodynia via activation of TGF-β-related pathway in macrophages. J Clin Invest. 2023;133: pubmed publisher
Kieu T, Pierre L, Derang xe8 re V, Perrey S, Truntzer C, Jalil A, et al. Downregulation of Elovl5 promotes breast cancer metastasis through a lipid-droplet accumulation-mediated induction of TGF-β receptors. Cell Death Dis. 2022;13:758 pubmed publisher
Fu Y, Wang Z, Yu B, Lin Y, Huang E, Liu R, et al. Intestinal CD11b+ B Cells Ameliorate Colitis by Secreting Immunoglobulin A. Front Immunol. 2021;12:697725 pubmed publisher
Osman A, Yan B, Li Y, Pavelko K, Quandt J, Saadalla A, et al. TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer. Nat Immunol. 2021;22:1152-1162 pubmed publisher
Xu H, Agalioti T, Zhao J, Steglich B, Wahib R, Vesely M, et al. The induction and function of the anti-inflammatory fate of TH17 cells. Nat Commun. 2020;11:3334 pubmed publisher
Sun X, Cui Y, Feng H, Liu H, Liu X. TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity. J Exp Med. 2019;216:2819-2837 pubmed publisher
Yu P, Huang Y, Xu C, Lin L, Han Y, Sun W, et al. Downregulation of CXCL12 in mesenchymal stromal cells by TGF? promotes breast cancer metastasis. Oncogene. 2017;36:840-849 pubmed publisher
Lewis G, Wehrens E, Labarta Bajo L, Streeck H, Zuniga E. TGF-? receptor maintains CD4 T helper cell identity during chronic viral infections. J Clin Invest. 2016;126:3799-3813 pubmed publisher
product information
brand :
R&D Systems
master code :
FAB532P
SKU :
FAB532P-100UG
product name :
Mouse TGF┐▀ RII PE-conjugated Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse TGF¿ß RII PE-conjugated Antibody from R&D Systems is a goat polyclonal antibody to TGF-beta RII. This antibody reacts with mouse. The Mouse TGF¿ß RII PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Flow Cytomery.
target :
TGF-beta RII
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Polyclonal
conjugate :
Phycoerythrin
dilution :
Flow Cytometry 0.25-1 ug/10^6 cells
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse TGF┐▀ RII and S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TGF┐▀ RII, Ile24-Asp184, Accession # Q62312
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse TGF┐▀ RII in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) TGF┐▀ RII is observed and less than 1% cross-reactivity with recombinant mouse TGF┐▀ RI and rhTGF┐▀ RIII is observed.
gene symbol :
TGFBR2
top caption :
Detection of TGF-ss RII antibody in Mouse Splenocytes antibody by Flow Cytometry.
accessionNumbers :
Q62312
applications :
Flow Cytomery,Flow Cytometry
USD :
379 USD
alt names :
AAT3, EC 2.7.11, EC 2.7.11.30, FAA3, HNPCC6, LDS1B, LDS2B, MFS2, RIIC, TAAD2, tbetaR-II, TGF-beta receptor type II, TGF-beta receptor type IIB, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbetaRII, TGFbeta-RII, TGFBR2, TGF-bRII, TGFR-2, transforming growth factor beta receptor type IIC, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II (70/80kDa) isoform 1, transforming growth factor, beta receptor II (70/80kDa) isoform 2, transforming growth factor, beta receptor II (70-80kD), Transforming growth factor-beta receptor type II
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.