Human Notch-1 PE-conjugated Antibody | R&D Systems FAB5317P-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Notch-1 PE-conjugated Antibody

catalog :

FAB5317P-100

quantity :

100 Tests (also 25 Tests)

price :

389 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

527425

reactivity :

human

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Marchesini M, Gherli A, Montanaro A, Patrizi L, Sorrentino C, Pagliaro L, et al. Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia. Cell Chem Biol. 2020;27:678-697.e13 pubmed publisher
Teo Y, Rattanavirotkul N, Olova N, Salzano A, Quintanilla A, Tarrats N, et al. Notch Signaling Mediates Secondary Senescence. Cell Rep. 2019;27:997-1007.e5 pubmed publisher
Al Attar A, Alimova Y, Kirakodu S, Kozal A, Novak M, Stromberg A, et al. Activation of Notch-1 in oral epithelial cells by P. gingivalis triggers the expression of the antimicrobial protein PLA2-IIA. Mucosal Immunol. 2018;11:1047-1059 pubmed publisher
Baldoni S, Del Papa B, Dorillo E, Aureli P, De Falco F, Rompietti C, et al. Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia. Int J Cancer. 2018;143:958-970 pubmed publisher
Roti G, Qi J, Kitara S, Sanchez Martin M, Saur Conway A, Varca A, et al. Leukemia-specific delivery of mutant NOTCH1 targeted therapy. J Exp Med. 2018;215:197-216 pubmed publisher
Piggott K, Deng J, Warrington K, Younge B, Kubo J, Desai M, et al. Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis. Circulation. 2011;123:309-18 pubmed publisher

product information

master code :

FAB5317P

SKU :

FAB5317P-100

product name :

Human Notch-1 PE-conjugated Antibody

unit size :

100 Tests (also 25 Tests)

description :

The Human Notch-1 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Notch-1. This antibody reacts with human. The Human Notch-1 PE-conjugated Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Flow Cytometry.

target :

Notch-1

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

527425

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Notch-1, Ala19-Gln526, Accession # P46531

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Notch-1.

gene symbol :

NOTCH1

top caption :

Detection of Notch-1 antibody in U2OS Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

P46531

applications :

Flow Cytometry

USD :

389 USD

alt names :

EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, Notch1, TAN1, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1

storage :

Store the unopened product at 2 - 8░ C. Do not use past expiration date. Protect from light.

more info or order :

R&D Systems product webpage