product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse CXCR7/RDC-1 APC-conjugated Antibody
catalog :
FAB4227A-100
quantity :
100 Tests (also 25 Tests)
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
11G8
reactivity :
human, mouse
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 9
Reference
Trotta A, Tomassi S, Di Maiolo G, Ieran xf2 C, Vetrei C, D Alterio C, et al. Disulfide bond replacement with non-reducible side chain to tail macrolactamization for the development of potent and selective CXCR4 peptide antagonists endowed with flanking binding sites. Eur J Med Chem. 2024;276:116669 pubmed publisher
Sigmund E, Bauer A, Jakobs B, Tatliadim H, Tacconi C, Thelen M, et al. Reassessing the adrenomedullin scavenging function of ACKR3 in lymphatic endothelial cells. PLoS ONE. 2023;18:e0285597 pubmed publisher
Del Molino Del Barrio I, Wilkins G, Meeson A, Ali S, Kirby J. Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12. Int J Mol Sci. 2018;19: pubmed publisher
Armas González E, Domínguez Luis M, Díaz Martín A, Arce Franco M, Castro Hernandez J, Danelon G, et al. Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis. Arthritis Res Ther. 2018;20:114 pubmed publisher
Benredjem B, Girard M, Rhainds D, St Onge G, Heveker N. Mutational Analysis of Atypical Chemokine Receptor 3 (ACKR3/CXCR7) Interaction with Its Chemokine Ligands CXCL11 and CXCL12. J Biol Chem. 2017;292:31-42 pubmed publisher
Yu P, Huang Y, Xu C, Lin L, Han Y, Sun W, et al. Downregulation of CXCL12 in mesenchymal stromal cells by TGF? promotes breast cancer metastasis. Oncogene. 2017;36:840-849 pubmed publisher
Arieta Kuksin C, González Pérez G, Minter L. CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia. Blood. 2015;125:2087-94 pubmed publisher
Maussang D, Mujić Delić A, Descamps F, Stortelers C, Vanlandschoot P, Stigter van Walsum M, et al. Llama-derived single variable domains (nanobodies) directed against chemokine receptor CXCR7 reduce head and neck cancer cell growth in vivo. J Biol Chem. 2013;288:29562-72 pubmed publisher
Berahovich R, Zabel B, Penfold M, Lewén S, Wang Y, Miao Z, et al. CXCR7 protein is not expressed on human or mouse leukocytes. J Immunol. 2010;185:5130-9 pubmed publisher
image
image 1 :
R&D Systems FAB4227A-100 image 1
Detection of CXCR7/RDC-1 antibody in MCF-7 Human Cell Line antibody by Flow Cytometry.
product information
master code :
FAB4227A
SKU :
FAB4227A-100
product name :
Human/Mouse CXCR7/RDC-1 APC-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human/Mouse CXCR7/RDC-1 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CXCR7/RDC-1. This antibody reacts with human,mouse. The Human/Mouse CXCR7/RDC-1 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
CXCR7/RDC-1
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
11G8
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
Human CXCR7 encoding plasmid, Accession # P25106
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human CXCR7/RDC-1 in flow cytometry of five distinct human CXCR7 transfectants, but not their respective parental lines.
gene symbol :
CXCR7
top caption :
Detection of CXCR7/RDC-1 antibody in MCF-7 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P25106
applications :
Flow Cytometry
USD :
499 USD
alt names :
ACKR3, chemokine (C-X-C motif) receptor 7, Chemokine orphan receptor 1CMKOR1C-X-C chemokine receptor type 7, CMKOR1, CXCR7, CXC-R7, CXCR-7, G protein-coupled receptor, GPR159, GPR159G-protein coupled receptor 159, RDC-1, RDC1G-protein coupled receptor RDC1 homolog
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.