This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human IGF-I R/IGF1R PE-conjugated Antibody
catalog :
FAB391P
quantity :
25 Tests
price :
149 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
33255
reactivity :
human
application :
flow cytometry
citations: 5
Reference
Wang J, Shi G, Baptiste S, Yarotska M, Sindhu H, Wong C, et al. Quantification of IGF-1 Receptor May Be Useful in Diagnosing Polycythemia Vera-Suggestion to Be Added to Be One of the Minor Criterion. PLoS ONE. 2016;11:e0165299 pubmed publisher
Mancini M, Gariboldi M, Taiana E, Bonzi M, Craparotta I, Pagin M, et al. Co-targeting the IGF system and HIF-1 inhibits migration and invasion by (triple-negative) breast cancer cells. Br J Cancer. 2014;110:2865-73 pubmed publisher
Mirkina I, Hadzijusufovic E, Krepler C, Mikula M, Mechtcheriakova D, Strommer S, et al. Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R. PLoS ONE. 2014;9:e84417 pubmed publisher
Müller E, Dunstheimer D, Klammt J, Friebe D, Kiess W, Kratzsch J, et al. Clinical and functional characterization of a patient carrying a compound heterozygous pericentrin mutation and a heterozygous IGF1 receptor mutation. PLoS ONE. 2012;7:e38220 pubmed publisher
Raile K, Hille R, Laue S, Schulz A, Pfeifer G, Horn F, et al. Insulin-like growth factor I (IGF-I) stimulates proliferation but also increases caspase-3 activity, Annexin-V binding, and DNA-fragmentation in human MG63 osteosarcoma cells: co-activation of pro- and anti-apoptotic pathways by IGF-I. Horm Metab Res. 2003;35:786-93 pubmed
product information
brand :
R&D Systems
master code :
FAB391P
SKU :
FAB391P-025
product name :
Human IGF-I R/IGF1R PE-conjugated Antibody
description :
The Human IGF-I R/IGF1R PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IGF-I R/IGF1R. This antibody reacts with human. The Human IGF-I R/IGF1R PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
IGF-I R/IGF1R
category :
Primary Antibodies
unit size :
25 Tests
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
33255
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IGF-I R, Glu31-Asn932, Accession # P08069
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human IGF-I R in sandwich ELISAs and Western blots. In sandwich ELISAs, less than 0.15% cross-reactivity or interference was observed with recombinant human (rh) IGF-I, rhIGF-II, rhIL-3 R alpha , rhIL-9 R, and rhTGF-beta RII.
gene symbol :
IGF1R
catalog number base :
FAB391P
accessionNumbers :
P08069
applications :
Flow Cytometry
2020 USD :
149
2021 USD :
149 USD
alt names :
CD221, CD221 antigen, EC 2.7.10, EC 2.7.10.1, IGF1R, IGF-1R, IGF-I receptor, IGFIR, IGF-IR, IGFR, insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, JTK13, MGC142170, MGC142172, MGC18216, soluble IGF1R variant 1, soluble IGF1R variant 2
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.