product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Fibroblast Activation Protein alpha /FAP PE-conjugated Antibody
catalog :
FAB3715P-100
quantity :
100 Tests (also 25 Tests)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
427819
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 12
Reference
Guinn S, Kinny K xf6 ster B, Tandurella J, Mitchell J, Sidiropoulos D, Loth M, et al. Transfer Learning Reveals Cancer-Associated Fibroblasts Are Associated with Epithelial-Mesenchymal Transition and Inflammation in Cancer Cells in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2024;84:1517-1533 pubmed publisher
Ding Z, Sun S, Wang X, Yang X, Shi W, Huang X, et al. Nanobody-based trispecific T cell engager (Nb-TriTE) enhances therapeutic efficacy by overcoming tumor-mediated immunosuppression. J Hematol Oncol. 2023;16:115 pubmed publisher
Axemaker H, Plesselova S, Calar K, Jorgensen M, Wollman J, de la Puente P. Normal Uterine Fibroblast Are Reprogramed into Ovarian Cancer-Associated Fibroblasts by Ovarian Tumor-derived Conditioned Media. bioRxiv. 2023;: pubmed publisher
Arebro J, Towle R, Lee C, Bennewith K, Garnis C. Extracellular vesicles promote activation of pro-inflammatory cancer-associated fibroblasts in oral cancer. Front Cell Dev Biol. 2023;11:1240159 pubmed publisher
Sulaiman R, De P, Aske J, Lin X, Dale A, Koirala N, et al. Patient-Derived Primary Cancer-Associated Fibroblasts Mediate Resistance to Anti-Angiogenic Drug in Ovarian Cancers. Biomedicines. 2023;11: pubmed publisher
Sommerfeld L, Knuth I, Finkernagel F, Pesek J, Nockher W, Jansen J, et al. Prostacyclin Released by Cancer-Associated Fibroblasts Promotes Immunosuppressive and Pro-Metastatic Macrophage Polarization in the Ovarian Cancer Microenvironment. Cancers (Basel). 2022;14: pubmed publisher
Da Pieve C, Costa Braga M, Turton D, Valla F, Cakmak P, Plate K, et al. New Fully Automated Preparation of High Apparent Molar Activity 68Ga-FAPI-46 on a Trasis AiO Platform. Molecules. 2022;27: pubmed publisher
Lina I, Berges A, Ospino R, Davis R, Motz K, Tsai H, et al. Identifying Phenotypically Distinct Fibroblast Subsets in Type 2 Diabetes-Associated Iatrogenic Laryngotracheal Stenosis. Otolaryngol Head Neck Surg. 2022;166:712-719 pubmed publisher
Ali D, Alhattab D, Jafar H, Alzubide M, Sharar N, Bdour S, et al. Differential Marker Expression between Keratinocyte Stem Cells and Their Progeny Generated from a Single Colony. Int J Mol Sci. 2021;22: pubmed publisher
Voabil P, de Bruijn M, Roelofsen L, Hendriks S, Brokamp S, van den Braber M, et al. An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer. Nat Med. 2021;27:1250-1261 pubmed publisher
Montero J, Gstalder C, Kim D, Sadowicz D, Miles W, Manos M, et al. Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies. Nat Commun. 2019;10:5157 pubmed publisher
Huang Y, Zhou S, Huang Y, Zheng D, Mao Q, He J, et al. Isolation of Fibroblast-Activation Protein-Specific Cancer-Associated Fibroblasts. Biomed Res Int. 2017;2017:4825108 pubmed publisher
product information
brand :
R&D Systems
master code :
FAB3715P
SKU :
FAB3715P-100
product name :
Human Fibroblast Activation Protein alpha /FAP PE-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
seo description :
The Human Fibroblast Activation Protein alpha /FAP PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Fibroblast Activation Protein alpha/FAP. This antibody reacts with human. The Human Fibroblast Activation Protein alpha /FAP PE-conjugated Antibody has been validated for the following applications: MACS,Flow Cytometry,Immunocytochemistry.
target :
Fibroblast Activation Protein alpha/FAP
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
427819
conjugate :
Phycoerythrin
dilution :
Flow Cytometry 10 uL/10^6 cells
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Fibroblast Activation Protein alpha /FAP, Leu26-Asp760, Accession # Q12884
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Fibroblast Activation Protein alpha /FAP in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human DPP6 is observed.
gene symbol :
FAP
top caption :
Detection of Fibroblast Activation Protein a/FAP antibody in WI-38 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
Q12884
applications :
MACS,Flow Cytometry,Immunocytochemistry
USD :
459 USD
alt names :
170 kDa melanoma membrane-bound gelatinase, DKFZp686G13158, DPPIV, EC 3.4.21.-, FAP, FAPA, Fibroblast activation protein alpha, fibroblast activation protein, alpha, Integral membrane serine protease, seprase, vibronectin
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.