product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Fibroblast Activation Protein alpha /FAP APC-conjugated Antibody
catalog :
FAB3715A-100
quantity :
100 Tests (also 25 Tests)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
427819
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry, FACS
more info or order :
R&D Systems product webpage
citations: 10
Reference
Liu T, Huang C, Sun L, Chen Z, Ge Y, Ji W, et al. FAP+ gastric cancer mesenchymal stromal cells via paracrining INHBA and remodeling ECM promote tumor progression. Int Immunopharmacol. 2025;144:113697 pubmed publisher
Jia H, Moore M, Wadhwa M, Burns C. Human iPSC-Derived Endothelial Cells Exhibit Reduced Immunogenicity in Comparison With Human Primary Endothelial Cells. Stem Cells Int. 2024;2024:6153235 pubmed publisher
Hisada K, Kaneda Nakashima K, Shirakami Y, Kadonaga Y, Saito A, Watabe T, et al. Comparison Length of Linker in Compound for Nuclear Medicine Targeting Fibroblast Activation Protein as Molecular Target. Int J Mol Sci. 2024;25: pubmed publisher
Forsthuber A, Aschenbrenner B, Korosec A, Jacob T, Annusver K, Krajic N, et al. Cancer-associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy. Nat Commun. 2024;15:9678 pubmed publisher
Dong Y, Chen Y, Wang Y, Zhao X, Zi R, Hao J, et al. Cancer-associated fibroblasts derived fibronectin extra domain A promotes sorafenib resistance in hepatocellular carcinoma cells by activating SHMT1. Genes Dis. 2024;11:101330 pubmed publisher
Ambrosio M, Mosca G, Migliaccio T, Liguoro D, Nele G, Schonauer F, et al. Glucose Enhances Pro-Tumorigenic Functions of Mammary Adipose-Derived Mesenchymal Stromal/Stem Cells on Breast Cancer Cell Lines. Cancers (Basel). 2022;14: pubmed publisher
Pan Z, Xu T, Bao L, Hu X, Jin T, Chen J, et al. CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment. Mol Cancer. 2022;21:190 pubmed publisher
Cao L, Jiang H, Yang J, Mao J, Wei G, Meng X, et al. LncRNA MIR31HG is induced by tocilizumab and ameliorates rheumatoid arthritis fibroblast-like synoviocyte-mediated inflammation via miR-214-PTEN-AKT signaling pathway. Aging (Albany NY). 2021;13:24071-24085 pubmed publisher
Friedrich M, Pohin M, Jackson M, Korsunsky I, Bullers S, Rue Albrecht K, et al. IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies. Nat Med. 2021;27:1970-1981 pubmed publisher
Kumar V, Donthireddy L, Marvel D, Condamine T, Wang F, Lavilla Alonso S, et al. Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors. Cancer Cell. 2017;32:654-668.e5 pubmed publisher
product information
master code :
FAB3715A
SKU :
FAB3715A-100
product name :
Human Fibroblast Activation Protein alpha /FAP APC-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human Fibroblast Activation Protein alpha /FAP APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Fibroblast Activation Protein alpha/FAP. This antibody reacts with human. The Human Fibroblast Activation Protein alpha /FAP APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Flow Cytometry Control,FACS,Immunocytochemistry,Immunohistochemistry.
target :
Fibroblast Activation Protein alpha/FAP
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
427819
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Fibroblast Activation Protein alpha /FAP, Leu26-Asp760, Accession # Q12884
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Fibroblast Activation Protein alpha /FAP in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human DPP6 is observed.
gene symbol :
FAP
top caption :
Detection of Fibroblast Activation Protein a/FAP antibody in WI-38 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
Q12884
applications :
Flow Cytometry Control,Flow Cytometry,FACS,Immunocytochemistry,Immunohistochemistry
USD :
459 USD
alt names :
170 kDa melanoma membrane-bound gelatinase, DKFZp686G13158, DPPIV, EC 3.4.21.-, FAP, FAPA, Fibroblast activation protein alpha, fibroblast activation protein, alpha, Integral membrane serine protease, seprase, vibronectin
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.