product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CD44 v6 PE-conjugated Antibody
catalog :
FAB3660P
quantity :
100 Tests
price :
199 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
2F10
reactivity :
human, mouse
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 12
Reference
Calvo J, Naguibneva I, Kypraios A, Gilain F, Uzan B, Gaillard B, et al. High CD44 expression and enhanced E-selectin binding identified as biomarkers of chemoresistant leukemic cells in human T-ALL. Leukemia. 2025;39:323-336 pubmed publisher
Gong C, Gu Z, Zhang X, Xu Q, Mao G, Pei Z, et al. HMSCs exosome-derived miR-199a-5p attenuates sulfur mustard-associated oxidative stress via the CAV1/NRF2 signalling pathway. J Cell Mol Med. 2023;27:2165-2182 pubmed publisher
Nowak J, Bentele M, Kutle I, Zimmermann K, L xfc hmann J, Steinemann D, et al. CAR-NK Cells Targeting HER1 (EGFR) Show Efficient Anti-Tumor Activity against Head and Neck Squamous Cell Carcinoma (HNSCC). Cancers (Basel). 2023;15: pubmed publisher
Yan B, Mu Y, Cui M, Liu L. Clinicopathological significance and prognostic implication of CD44 and its splice variants (v3 and v6) in colorectal cancer. Transl Cancer Res. 2020;9:1215-1224 pubmed publisher
Jin H, Kim H. NK Cells Lose Their Cytotoxicity Function against Cancer Stem Cell-Rich Radiotherapy-Resistant Breast Cancer Cell Populations. Int J Mol Sci. 2021;22: pubmed publisher
Xia M, Duan L, Lu B, Pang Y, Pang Z. LncRNA AFAP1-AS1/miR-27b-3p/VEGF-C axis modulates stemness characteristics in cervical cancer cells. Chin Med J (Engl). 2021;134:2091-2101 pubmed publisher
Nicolazzo C, Loreni F, Caponnetto S, Magri V, Vestri A, Zamarchi R, et al. Baseline CD44v6-positive circulating tumor cells to predict first-line treatment failure in patients with metastatic colorectal cancer. Oncotarget. 2020;11:4115-4122 pubmed publisher
Wang X, Wang R, Bai S, Xiong S, Li Y, Liu M, et al. Musashi2 contributes to the maintenance of CD44v6+ liver cancer stem cells via notch1 signaling pathway. J Exp Clin Cancer Res. 2019;38:505 pubmed publisher
Whelan K, Chandramouleeswaran P, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, et al. Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance. Oncogene. 2017;36:4843-4858 pubmed publisher
Okada T, Nakamura T, Watanabe T, Onoda N, Ashida A, Okuyama R, et al. Coexpression of EpCAM, CD44 variant isoforms and claudin-7 in anaplastic thyroid carcinoma. PLoS ONE. 2014;9:e94487 pubmed publisher
Krishnamachary B, Penet M, Nimmagadda S, Mironchik Y, Raman V, Solaiyappan M, et al. Hypoxia regulates CD44 and its variant isoforms through HIF-1? in triple negative breast cancer. PLoS ONE. 2012;7:e44078 pubmed publisher
McFadden C, Morgan R, Rahangdale S, Green D, Yamasaki H, Center D, et al. Preferential migration of T regulatory cells induced by IL-16. J Immunol. 2007;179:6439-45 pubmed
product information
master code :
FAB3660P
SKU :
FAB3660P
product name :
Human CD44 v6 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human CD44 v6 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CD44. This antibody reacts with human,mouse. The Human CD44 v6 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Bioassay.
target :
CD44
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
2F10
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Recombinant human CD44 v3-10
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human,Mouse
specificity :
Detects human CD44 v6 in Western blots. By flow cytometry analysis using a panel of CD44-transfected COS cells (9), monoclonal antibody clone 2F10 was deduced to be specific for human CD44 protein isoforms containing variant exon 6 (CD44 v6).
gene symbol :
CD44
top caption :
Detection of CD44 v6 antibody in Human Blood Monocytes antibody by Flow Cytometry.
applications :
Flow Cytometry,Bioassay
USD :
199 USD
alt names :
CD44, CD44 antigen, CD44 molecule (Indian blood group), CD44R, CDw44, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan sulfate proteoglycan, Hermes antigen, homing function and Indian blood group system, HUTCH-I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU2CD44 antigen (homing function and Indian blood group system), MDU3, MDU3CDW44, MIC4, MIC4MGC10468, MUTCH-I, Pgp1, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.