product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse/Rat CD31/PECAM-1 Alexa Fluor« 488-conjugated Antibody
catalog :
FAB3628G-100
quantity :
100 Tests (also 25 Tests)
price :
379 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
AF488
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2f
Zhang D, Huang J, Sun X, Chen H, Huang S, Yang J, et al. Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway. Nat Commun. 2021;12:4391 pubmed publisher
Li H, Han D, Ao R, Cai Z, Zhu G, Wu D, et al. Tanshinone IIA attenuates osteoarthritis via inhibiting aberrant angiogenesis in subchondral bone. Arch Biochem Biophys. 2024;753:109904 pubmed publisher
Xu H, Liu J, Zheng C, Liu L, Ma C, Tian J, et al. Region-specific sympatho-adrenergic regulation of specialized vasculature in bone homeostasis and regeneration. iScience. 2023;26:107455 pubmed publisher
Ruan Z, Yin H, Wan T, Lin Z, Zhao S, Long H, et al. Metformin accelerates bone fracture healing by promoting type H vessel formation through inhibition of YAP1/TAZ expression. Bone Res. 2023;11:45 pubmed publisher
Li H, Hu S, Wu R, Zhou H, Zhang K, Li K, et al. 11β-Hydroxysteroid Dehydrogenase Type 1 Facilitates Osteoporosis by Turning on Osteoclastogenesis through Hippo Signaling. Int J Biol Sci. 2023;19:3628-3639 pubmed publisher
Ni S, Luo Z, Fan Y, Zhang W, Peng W, Zhang H. Alteration of m6A epitranscriptomic tagging of ribonucleic acids after spinal cord injury in mice. Front Neurosci. 2022;16:904573 pubmed publisher
Termini C, Pang A, Fang T, Roos M, Chang V, Zhang Y, et al. Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution. Nat Commun. 2021;12:6990 pubmed publisher
Shen K, Liu X, Qin H, Chai Y, Wang L, Yu B. HA-g-CS Implant and Moderate-intensity Exercise Stimulate Subchondral Bone Remodeling and Promote Repair of Osteochondral Defects in Mice. Int J Med Sci. 2021;18:3808-3820 pubmed publisher
Hoffmann J, Luxan G, Abplanalp W, Glaser S, Rasper T, Fischer A, et al. Post-myocardial infarction heart failure dysregulates the bone vascular niche. Nat Commun. 2021;12:3964 pubmed publisher
Chen P, Zhang G, Jiang S, Ning Y, Deng B, Pan X, et al. Mechanosensitive Piezo1 in endothelial cells promotes angiogenesis to support bone fracture repair. Cell Calcium. 2021;97:102431 pubmed publisher
Wu M, Liu X, Li Z, Huang X, Guo H, Guo X, et al. SHED aggregate exosomes shuttled miR-26a promote angiogenesis in pulp regeneration via TGF-β/SMAD2/3 signalling. Cell Prolif. 2021;54:e13074 pubmed publisher
Liu X, Chai Y, Liu G, Su W, Guo Q, Lv X, et al. Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis. Nat Commun. 2021;12:1832 pubmed publisher
Chen J, Li M, Liu A, Zheng C, Bao L, Chen K, et al. Gli1+ Cells Couple with Type H Vessels and Are Required for Type H Vessel Formation. Stem Cell Reports. 2020;15:110-124 pubmed publisher
Su J, Chai Y, Ji Z, Xie Y, Yu B, Zhang X. Cellular senescence mediates the detrimental effect of prenatal dexamethasone exposure on postnatal long bone growth in mouse offspring. Stem Cell Res Ther. 2020;11:270 pubmed publisher
Liu A, Zhang L, Chen J, Sui B, Liu J, Zhai Q, et al. Mechanosensing by Gli1+ cells contributes to the orthodontic force-induced bone remodelling. Cell Prolif. 2020;53:e12810 pubmed publisher
Peng Y, Lv S, Li Y, Zhu J, Chen S, Zhen G, et al. Glucocorticoids Disrupt Skeletal Angiogenesis Through Transrepression of NF-κB-Mediated Preosteoclast Pdgfb Transcription in Young Mice. J Bone Miner Res. 2020;35:1188-1202 pubmed publisher
Fu R, Lv W, Xu Y, Gong M, Chen X, Jiang N, et al. Endothelial ZEB1 promotes angiogenesis-dependent bone formation and reverses osteoporosis. Nat Commun. 2020;11:460 pubmed publisher
Singh A, Veeriah V, Xi P, Labella R, Chen J, Romeo S, et al. Angiocrine signals regulate quiescence and therapy resistance in bone metastasis. JCI Insight. 2019;4: pubmed publisher
Ji G, Xu R, Niu Y, Li N, Ivashkiv L, Bostrom M, et al. Vascular endothelial growth factor pathway promotes osseointegration and CD31hiEMCNhi endothelium expansion in a mouse tibial implant model: an animal study. Bone Joint J. 2019;101-B:108-114 pubmed publisher
Balzano M, De Grandis M, Vu Manh T, Chasson L, Bardin F, Farina A, et al. Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche. Cell Rep. 2019;26:3257-3271.e8 pubmed publisher
Li C, Chai Y, Wang L, Gao B, Chen H, Gao P, et al. Programmed cell senescence in skeleton during late puberty. Nat Commun. 2017;8:1312 pubmed publisher
Wang L, Jia P, Shan Y, Hao Y, Wang X, Jiang Y, et al. Synergistic protection of bone vasculature and bone mass by desferrioxamine in osteoporotic mice. Mol Med Rep. 2017;16:6642-6649 pubmed publisher
Kijani S, Vázquez A, Levin M, Borén J, Fogelstrand P. Intimal hyperplasia induced by vascular intervention causes lipoprotein retention and accelerated atherosclerosis. Physiol Rep. 2017;5: pubmed publisher
Langen U, Pitulescu M, Kim J, Enriquez Gasca R, Sivaraj K, Kusumbe A, et al. Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol. 2017;19:189-201 pubmed publisher
Ramasamy S, Kusumbe A, Schiller M, Zeuschner D, Bixel M, Milia C, et al. Blood flow controls bone vascular function and osteogenesis. Nat Commun. 2016;7:13601 pubmed publisher
Zhou J, Rogers J, Lee S, Sun D, Yao H, Mao J, et al. Oral Mucosa Harbors a High Frequency of Endothelial Cells: A Novel Postnatal Cell Source for Angiogenic Regeneration. Stem Cells Dev. 2017;26:91-101 pubmed publisher
Kusumbe A, Ramasamy S, Itkin T, Mäe M, Langen U, Betsholtz C, et al. Age-dependent modulation of vascular niches for haematopoietic stem cells. Nature. 2016;532:380-4 pubmed publisher
product information
master code :
FAB3628G
SKU :
FAB3628G-100
product name :
Mouse/Rat CD31/PECAM-1 Alexa Fluor« 488-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Mouse/Rat CD31/PECAM-1 Alexa Fluor® 488-conjugated Antibody from R&D Systems is a goat polyclonal antibody to CD31/PECAM-1. This antibody reacts with human,mouse,rat. The Mouse/Rat CD31/PECAM-1 Alexa Fluor® 488-conjugated Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Flow Cytometry,Immunohistochemistry-Frozen.
target :
CD31/PECAM-1
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Polyclonal
conjugate :
Alexa Fluor 488
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse CD31/PECAM-1, Glu18-Lys590, Accession # Q08481
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects mouse CD31/PECAM-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human CD31 and recombinant porcine CD31 is observed. Detects mouse CD31 and rat CD31 in flow cytometry.
gene symbol :
PECAM1
top caption :
Detection of CD31/PECAM-1 antibody in Mouse Splenocytes antibody by Flow Cytometry.
accessionNumbers :
Q08481
applications :
Immunohistochemistry,Immunocytochemistry,Flow Cytometry,Immunohistochemistry-Frozen
USD :
379 USD
alt names :
adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA', PECA1, PECAM1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule-1, platelet/endothelial cell adhesion molecule
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.