product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human HGFR/c-MET PE-conjugated Antibody
catalog :
FAB3582P
quantity :
100 Tests
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
95106
reactivity :
human
application :
western blot, flow cytometry
more info or order :
citations: 11
Reference
De Bacco F, Orzan F, Crisafulli G, Prelli M, Isella C, Casanova E, et al. Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas. Cell Rep. 2023;42:112816 pubmed publisher
Coelho P, Hesketh G, Pedersen A, Kuzmin E, Fortier A, Bell E, et al. Endosomal LC3C-pathway selectively targets plasma membrane cargo for autophagic degradation. Nat Commun. 2022;13:3812 pubmed publisher
Boschert V, Teusch J, Aljasem A, Schmucker P, Klenk N, Straub A, et al. HGF-Induced PD-L1 Expression in Head and Neck Cancer: Preclinical and Clinical Findings. Int J Mol Sci. 2020;21: pubmed publisher
Wang S, Li R, Ng T, Luthria G, Oudin M, Prytyskach M, et al. Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy. Sci Adv. 2020;6:eaaz8521 pubmed publisher
Jo E, Lee Y, Lee H, Park J, Park H, Choi Y, et al. Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells. BMC Cancer. 2019;19:496 pubmed publisher
Penchev V, Chang Y, Begum A, Ewachiw T, Gocke C, Li J, et al. Ezrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma. Mol Cancer Res. 2019;17:929-936 pubmed publisher
Pillay S, Meyer N, Puschnik A, Davulcu O, Diep J, Ishikawa Y, et al. An essential receptor for adeno-associated virus infection. Nature. 2016;530:108-12 pubmed publisher
Jarantow S, Bushey B, Pardinas J, Boakye K, Lacy E, Sanders R, et al. Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor × c-MET Bispecific Antibody. J Biol Chem. 2015;290:24689-704 pubmed publisher
Tervonen T, Belitškin D, Pant S, Englund J, Marques E, Ala Hongisto H, et al. Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. Oncogene. 2016;35:1832-46 pubmed publisher
Ekert J, Johnson K, Strake B, Pardinas J, Jarantow S, Perkinson R, et al. Three-dimensional lung tumor microenvironment modulates therapeutic compound responsiveness in vitro--implication for drug development. PLoS ONE. 2014;9:e92248 pubmed publisher
Mirkina I, Hadzijusufovic E, Krepler C, Mikula M, Mechtcheriakova D, Strommer S, et al. Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R. PLoS ONE. 2014;9:e84417 pubmed publisher
product information
master code :
FAB3582P
SKU :
FAB3582P
product name :
Human HGFR/c-MET PE-conjugated Antibody
unit size :
100 Tests
description :
The Human HGFR/c-MET PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to HGFR/c-MET. This antibody reacts with human. The Human HGFR/c-MET PE-conjugated Antibody has been validated for the following applications: Western Blot,Flow Cytometry.
target :
HGFR/c-MET
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
95106
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human HGF R/c-MET, Glu25-Thr932, Accession # P08581
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human HGF R/c-MET.
gene symbol :
MET
top caption :
Detection of HGF R/c-MET antibody in MDA-MB-231 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P08581
applications :
Western Blot,Flow Cytometry
USD :
439 USD
alt names :
AUTS9, c-Met, cMET, EC 2.7.10, EC 2.7.10.1, hepatocyte growth factor receptor, HGF R, HGF receptor, HGF/SF receptor, HGFR, MET, Met (c-Met), met proto-oncogene (hepatocyte growth factor receptor), met proto-oncogene tyrosine kinase, oncogene MET, Proto-oncogene c-Met, RCCP2, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.