product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human VEGFR3/Flt-4 APC-conjugated Antibody
catalog :
FAB3492A
quantity :
100 Tests
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
54733
reactivity :
human
application :
flow cytometry
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; tbl 1
Zomerman W, Plasschaert S, Diks S, Lourens H, Meeuwsen de Boer T, Hoving E, et al. Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines. PLoS ONE. 2015;10:e0141381 pubmed publisher
  • flow cytometry; human
Fiorio Pla A, Brossa A, Bernardini M, Genova T, Grolez G, Villers A, et al. Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib. BMC Cancer. 2014;14:939 pubmed publisher
  • flow cytometry; human
Roorda B, ter Elst A, Scherpen F, Meeuwsen de Boer T, Kamps W, de Bont E. VEGF-A promotes lymphoma tumour growth by activation of STAT proteins and inhibition of p27(KIP1) via paracrine mechanisms. Eur J Cancer. 2010;46:974-82 pubmed publisher
Betterman K, Sutton D, Secker G, Kazenwadel J, Oszmiana A, Lim L, et al. Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow. J Clin Invest. 2020;130:3315-3328 pubmed publisher
Witkowska M, Majchrzak A, Cebula Obrzut B, Wawrzyniak E, Robak T, Smolewski P. The distribution and potential prognostic value of SMAD protein expression in chronic lymphocytic leukemia. Tumour Biol. 2017;39:1010428317694551 pubmed publisher
Sie M, den Dunnen W, Lourens H, Meeuwsen de Boer T, Scherpen F, Zomerman W, et al. Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma. PLoS ONE. 2015;10:e0122555 pubmed publisher
Norton K, Han Z, Popel A, Pandey N. Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells. Onco Targets Ther. 2014;7:1571-82 pubmed publisher
Weidenaar A, ter Elst A, Kampen K, Meeuwsen de Boer T, Kamps W, Schuringa J, et al. Impaired long-term expansion and self-renewal potential of pediatric acute myeloid leukemia-initiating cells by PTK787/ZK 222584. Mol Cancer Res. 2013;11:339-48 pubmed publisher
Nilsson M, Zage P, Zeng L, Xu L, Cascone T, Wu H, et al. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors. Oncogene. 2010;29:2938-49 pubmed publisher
Bennuru S, Nutman T. Lymphangiogenesis and lymphatic remodeling induced by filarial parasites: implications for pathogenesis. PLoS Pathog. 2009;5:e1000688 pubmed publisher
product information
master code :
FAB3492A
SKU :
FAB3492A
product name :
Human VEGFR3/Flt-4 APC-conjugated Antibody
unit size :
100 Tests
description :
The Human VEGFR3/Flt-4 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to VEGFR3/Flt-4. This antibody reacts with human. The Human VEGFR3/Flt-4 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
VEGFR3/Flt-4
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
54733
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human VEGF R3/Flt-4, Tyr25-Ile776, Accession # P35916
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human VEGF R3/Flt-4 in direct ELISAs.
gene symbol :
FLT4
top caption :
Detection of VEGF R3/Flt-4 antibody in HUVEC Human Cells antibody by Flow Cytometry.
accessionNumbers :
P35916
applications :
Flow Cytometry
USD :
449 USD
alt names :
EC 2.7.10, EC 2.7.10.1, Flt-4, FLT4, fms-related tyrosine kinase 4, LMPH1A, PCLFLT41, soluble VEGFR3 variant 1, soluble VEGFR3 variant 2, soluble VEGFR3 variant 3, Tyrosine-protein kinase receptor FLT4, vascular endothelial growth factor receptor 3, VEGF R3, VEGFR-3, VEGFR3Fms-like tyrosine kinase 4
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.